Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

New application of collagen chelate

A collagen and chelate technology, applied in peptide/protein components, medical preparations containing active ingredients, applications, etc., can solve problems such as increasing bone mass

Inactive Publication Date: 2010-07-14
顾凌洁 +1
View PDF1 Cites 17 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no relevant report on the use of collagen chelates to increase bone mass and improve bone strength

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • New application of collagen chelate
  • New application of collagen chelate
  • New application of collagen chelate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The preparation of embodiment 1 collagen calcium chelate of the present invention

[0022] The collagen chelate of the present invention is prepared according to the method disclosed in the patent US2007 / 0087039A1.

[0023] Place the commercial type I or type III collagen derived from bovine hide in a large water tank, and add protease under stirring conditions.

[0024] Using MS-HPLC and / or filters of appropriate specifications, control the digestion conditions so that the average molecular weight of the collagen hydrolyzate produced is in the range of 1-3KD, and separate the collagen fragments of the set size; inactivate the enzyme, filter the solution, and In the filtrate, add soluble inorganic matter, such as adding calcium carbonate under acidic conditions (such as adding calcium carbonate in hydrochloric acid solution to generate calcium chloride); after mixing, stir for 4-5 hours, adjust the pH value to 8.5 with sodium hydroxide, The collagen calcium chelate pre...

Embodiment 2

[0026] According to the technical operation of Example 1, the animal skin can be derived from cowhide, pig or fresh skin of other animals, and the skin needs to be degreased, cut into small pieces, and washed in a mixing tank.

Embodiment 3

[0028] According to the process operation of Example 1, type I or type III collagen can be replaced by gel.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Molecular weightaaaaaaaaaa
Molecular weightaaaaaaaaaa
Molecular weightaaaaaaaaaa
Login to View More

Abstract

The invention relates to application of collagen chelate in the preparation of medicament or food for enhancing bone quality. The medicament or food can enhance bone strength, can enhance bone strength and bone density at the same time and can be used for curing and / or preventing osteoporosis. The collagen chelate is a metalloprotein conjugate; compared with calcium carbonate (CaCO3) with the same calcium concentration, the collagen chelate can enhance the bone density by 4.4 percent and enhance the bone strength by 9.9 percent; and compared with a mixture of collagen and calcium carbonate (CaCO3) with the same concentration of collagen and calcium carbonate, the collagen chelate has a more obvious effect.

Description

technical field [0001] The invention relates to a new application of the collagen chelate, in particular, an application in preparing medicine or food for enhancing bone strength. Background technique [0002] Fracture refers to a disease in which the bone is partially or completely broken due to trauma or pathology. Its main clinical manifestations are localized pain and tenderness at the fracture site, local swelling and ecchymosis, and partial or complete limb function. Loss; complete bone mass may lead to limb deformities and abnormal activities. Osteoporosis (OP) is one of the common clinical bone diseases, which is characterized by low bone mass and microstructural degeneration and destruction of bone tissue, leading to increased bone fragility, decreased bone strength and easy fractures. The treatment of osteoporosis is to relieve bone pain, enhance bone strength, and reduce the incidence of fractures, among which reducing the incidence of fractures is the most impor...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K38/39A61P19/08A61P19/10A23L1/305A23L33/17
Inventor 顾凌洁李世海
Owner 顾凌洁
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com