The invention discloses a granular preparation for promoting blood circulation, dredging collaterals and relieving pain, a preparation method of the granular preparation, and a quality control method of the Chinese traditional medicine. The granular preparation of the invention is prepared from pharmaceutical excipients and a Chinese traditional medicine composition prepared from the following raw materials in parts by weight: 160-240 parts of white peony root, 40-60 parts of kudzu root, 40-60 parts of peach kernel, 40-60 parts of safflower, 40-60 parts of mastic, 40-60 parts of myrrh, 55-95 parts of teasel root, 55-95 parts of cibot rhizome, 55-95 parts of lycopodium clavatum, 40-60 parts of achyranthes, 40-60 parts of rehmannia and 15-35 parts of licorice. The granular preparation of the invention has stable granulation process and high quality controllability. The clinical test shows that the clinical total effective rate of the granular preparation of the invention for treating cervical spondylosis is 98.88%, the total effective rate of the control medicine for treating cervical spondylosis is 97.10%, and the state of an illness and main symptoms are improved obviously after treating. The effective rate for treating sciatica is 75.3%, the effective rate for treating hyperosteogeny is 82.7%, the effective rate for treating headache and dizziness caused by cervical spondylosis is 87.6%, the effective rate for treating waist pain and limitation of motion is 91.4%, the effective rate for treating shoulder and neck tenderness is 92.5%, the effective rate for treating neck pain and limitation of motion is 96.2%, and the effective rate for treating acroanesthesia is 98.5%. The clinical treatment effect of the granular preparation of the invention applied after the operation of prolapse of lumbar intervertebral disc (PLID) is as follows: the recovery rate of the sample group of the invention is 86.7%, and the recovery rate of the control group is 61%.