The invention belongs to the fields of measurement and detection, particularly relates to a centering and leveling work platform for a high-precision cylindricity measuring instrument and aims to provide the centering and leveling work platform which has the advantages of simpler structure, small regulating resistance and high feeding precision. The centering and leveling work platform comprises a centering device, a leveling device and a support device, wherein the centering device and the leveling device are mounted on the support device, the centering of the work platform is implemented by the centering device, and the leveling of the work platform is implemented by the leveling device. Centering is carried out through the adoption of a bevel gear steering box 5, a centering worm gear box 7 and a centering feeding head 22, and the input-output angle of the worm gear box is converted by a bevel gear. Besides, a spring is utilized to apply a certain pre-tightening force, centering shift is transmitted through the rolling of steel balls in a centering ball disc, and sliding friction is replaced by rolling friction, so that the resistance is reduced, and the error is reduced to a certain degree, therefore, the centering precision is improved.