The invention relates to a
traditional Chinese medicine composition for treating
knee joint degenerative change and application thereof. The
traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of radix angelicae pubescentis, 10-20 parts of radix clematidis, 3-9 parts of prepared kusnezoff
monkshood root, 25-35 parts of garden
balsam stem, 10-20 parts of
kadsura pepper stem, 10-20 parts of
cassia twig, 10-20 parts of caulis spatholobi, 10-20 parts of
cynanchum paniculatum, 10-20 parts of
lycopodium clavatum, 5-15 parts of safflower
carthamus and 10-20 parts of cortex acanthopanacis. The radix angelicae pubescentis, radix clematidis,
cynanchum paniculatum and
cassia twig have the effects of warming and dredging channels and removing
paralysis and are used as monarch drugs; the cortex acanthopanacis, prepared kusnezoff
monkshood root, safflower
carthamus and caulis spatholobi have the effects of dispelling cold and dampness and promoting
blood circulation to arrest pain and are used as ministerial drugs; the
lycopodium clavatum and garden
balsam stem have the effects of relaxing muscles and tendons and relieving pain and are used as
adjuvant drugs; the
kadsura pepper stem has the effect of dredging channels and is used as a conductant
drug; and all the drugs supplement each other and have a synergistic effect. Animal experiments show that the
traditional Chinese medicine composition has a remarkable effect of treating the
knee joint degenerative change and can be used for remarkably improving the
knee joint pain degree, joint movement degree, swelling degree and
gait of an
animal model.