The invention relates to health-care wine and a production method thereof. The health-care wine is prepared from the following ingredients, in parts by weight: 10-20 parts of radix glehniae, 5-15 parts of rhizoma smilacis glabrae, 5-15 parts of cortex eucommiae, 5-15 parts of radix angelicae sinensis, 2-10 parts of radix achyranthis bidentatae, 5-15 parts of radix glycyrrhizae, 5-15 parts of radixpaeoniae alba, 2-10 parts of fructus anisi stellati, 1-8 parts of cortex cinnamomi, 2-10 parts of radix angelicae pubescentis, 2-10 parts of fructus chaenomelis, 5-15 parts of radix rehmanniae preparata, 2-10 parts of rhizoma seu radix notopterygii, 10-20 parts of semen ziziphi spinosae, 5-15 parts of rhizoma chuanxiong, 5-15 parts of radix saposhnikoviae, 2-8 pieces of fructus jujubae, 2-10 parts of radix dipsaci, 5-15 parts of radix gentianae macrophyllae, 5-15 parts of tangerine peel and 5-15 parts of fructus lycii. The health-care wine prepared by adopting the method is clear in wine body, the color is purplish red, the taste is sweet, the mouthfeel is good, and the wine has the very good effects of soothing the nerves and be healthy to the brain, strengthening tendons and bones, reducing fatigue and nourishing physique, has the efficacy of invigorating the circulation of blood, reducing the hazy feeling of old people, so that the old people are conscious, and has the special effect on soreness of waist and leg pains. The health-care wine is particularly suitable for treating diseases of rheumatic arthritis, hyperostosis, sourness of waist and leg pains and insomnia.