The invention discloses a
piperazine-containing
ferulic acid derivative and a preparation method and application thereof, and belongs to the technical field of
drug synthesis and agricultural
disease control, the structural general formula of the
piperazine-containing
ferulic acid derivative is shown in the specification, in the formula, R1 is ethyl, allyl,
isopropyl,
propynyl, benzyl, o-methylbenzyl, m-methylbenzyl and o-fluorobenzyl; R2 is ethyl
sulfonyl, 4-methyl benzenesulfonyl, 4-nitrobenzenesulfonyl, 4-
trifluoromethyl benzenesulfonyl, 4-fluorobenzenesulfonyl, 2, 5-dichlorobenzenesulfonyl, 4-bromobenzenesulfonyl, 4-
bromine-3-
trifluoromethyl benzenesulfonyl, 3-
trifluoromethyl benzoyl, 4-fluorobenzoyl, 2-fluorobenzoyl, 4-methoxybenzoyl, 5-chlorovaleryl, 4-chlorobutyryl, 4-fluorobenzyl, 2-methoxybenzyl, 3, 4, 4-trifluorobutyl-3-
alkene 1-yl, 2-methoxy-2-oxoethyl, 2-oxo-2-phenylethyl. The
drug molecule is high in activity, the inhibitory activity on TMV and CMV is remarkable, the structure of the
drug is derived from natural products, and the drug is
environmentally friendly, easy to metabolize and degrade, simple and safe in preparation process and relatively stable in physicochemical property.