85results about How to "Reduce writhing" patented technology

The invention discloses a lignum naucleae leaf extract which is characterized in that the extract is obtained by using one of the following methods: (1) the lignum naucleae leaf extract is obtained by water extraction and impurity removal of traditional Chinese medicine lignum naucleae leaves; (2) the lignum naucleae leaf extract is obtained by alcohol extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves; (3) the lignum naucleae leaf extract is obtained by lipophilic organic solvent extraction and impurity removal of the traditional Chinese medicine lignum naucleae leaves, and the lipophilic organic solvent includes but not limited by n-butyl alcohol or ethyl acetate. The invention further discloses a preparation method of the lignum naucleae leaf extract, a preparation and a new purpose. The lignum naucleae leaf extract of the invention has exact effects of clearing heat and removing toxin. The extraction process of the invention is simple and reasonable, which can obtain the effective parts. The invention opens up a precedent of obtaining the lignum naucleae leaf extract from the lignum naucleae leaves to be used for the drugs for clearing heat and removing toxin, which can not only ease the shortage of raw materials, but is also conductive to the sustainable and rational development, utilization and protection of lignum naucleae resources.

The invention discloses a sinomenine vesicle and a preparation method thereof, a preparation containing the sinomenine vesicle and a preparation method of the preparation, which belong to the field of medicament preparations. The sinomenine vesicle is prepared from sinomenine, a nonionic surfactant and an additive. The sinomenine vesicle is preferably prepared into external gel. A sinomenine transdermal administration external preparation has a unique advantage to the medicament. Due to the application of a novel vesicle administration system, transdermal absorption of the medicament is improved, and a clinical curative effect is enhanced. The sinomenine vesicle can be used for treating rheumatism, rheumatoid arthritis, a glomerular disease, hyperosteogeny, spondylitis, arrhythmia, systemic lupus erythematosus, a heroin addict withdrawal symptom and the like.

The invention relates to a gallbladder wood leaf composition containing strictosamide. The gallbladder wood leaf composition is characterized in that the gallbladder wood leaf composition is prepared by combining alkaloid and flavonoid extracted from gallbladder wood leaf; the alkaloid contains strictosamide,10-hydroxy-strictosamide and short snakeroot glucoside; the flavonoid contains kaempferol-3-O-rutinoside and rutin; and the total weight of the three alkaloid and flavonoid is 50-98% of that of the composition, and the ratio of the total weight of the three alkaloid and the total weight of the flavonoid is (10-0.7):(0.5-10). The invention also discloses a preparation of the composition. The composition provided by the invention can play the role of clearing away heat and toxic materials and relieving swelling and pain, and can treat diseases such as acute tonsillitis, acute pharyngitis, acute conjunctivitis, upper respiratory tract infection or chronic pelvic inflammatory disease and appendagitis; and can cure slight and medium pain.

The present invention discloses a kind of Radix bupleuri dripping pill and its preparation process. Radix bupleuri is twice refluxed in water, the extracted liquid is merged, concentrated, alcohol deposited and filtered to recover alcohol and obtain Radix bupleuri extractum, and the Radix bupleuri extractum is mixed with supplementary material and prepared into the dripping pill. The present invention also discloses the pharmacological effect of the Chinese medicine.

A Chinese medicine for treating cold is proportionally prepared from bupleurum root, scutellaria root, pueria root and liquorice root. Its preparing process and its quality control method are also disclosed.

The medicine for treating prostatitis is prepared with sun plant, red peony root, patrinia herb, achyranthes root, orange seed and other two kinds of Chinese medicinal materials, and through conventional preparation process. Pharmacological experiment shows that the medicine has inflammation diminishing and pain relieving effect, and prostatitis treating effect.

The invention relates to a compound electret membrane, a preparation method thereof and the use thereof and belongs to the field of medical appliances. The compound electret membrane is produced from a porous membrane PTFE, FEP, PP and a blood-activating clot-dispersing Chinese medicament which is an ethanolic extract of notoginseng root, or dragon's blood or a pharmaceutical composition of the ethanolic extract of notoginseng root and the dragon's blood. The method adopts a melting process to prepare a PTFE / FEP electret membrane, adopts a corona induced plasma chemical process to make an electret and compounds a PP membrane and the PTFE / FEP electret membrane which carry the blood-activating clot-dispersing Chinese medicament to produce a novel compound electret membrane. The obtained compound electret membrane has the effects of quickly reliving pain, activating blood and dispersing clot, resisting inflammatory, promoting fracture healing and microcirculation, improving Joint movement and functions and suppressing arthrosis. The compound electret membrane is applicable to the symptoms of primary or secondary arthropathy, osteoarthropathy, sports injury, lumbago, tenosynovitis, osteoporosis, hyperosteogeny, rheumatoid arthritis, and the like.

The present invention relates to a Chinese medicine preparation prepared with smoothfruit ventilago root and stem, Chuanlonggu and starch in certain weight proportion. The preparation process of the Chinese medicine preparation includes twice decoction of smoothfruit ventilago root and stem and Chuanlonggu, filtering, concentrating filtrate to obtain extractum, adding starch, pelletizing, drying, tabletting and coating. The Chinese medicine preparation has the functions of eliminating wind evil and wetness evil, promoting blood circulation, dredging meridian, dispelling cold evil and relieving pain. It is used in treating rheumatic arthritis and rheumatic arthralgia, and has obvious and determined curative effect and no toxic side effect.

The tranquilizing Qiye dripping pill is prepared with arasaponin and water soluble matrix in the ratio of 1 to 1-5 and through mixing, water bath treatment, dissolving, dropping into condensing agent. The tranquilizing Qiye dripping pill has the functions of benefiting vital energy, tranquilizing mind, promoting blood circulation, stopping pain and hypnogenesis, and thus has excellent insomnia treating effect. The preparation process of the present invention has high medicine quality, high bioavailability and many other advantages.

A Chinese medicine for treating menalgia is prepared from 9 Chinese-medicinal materials including astragalus root, Chinese angelica root, white peony root, Chuan-xiong rhizome, etc. its preparing process is also disclosed.

The invention relates to an application of compound donkey-hide gelatin pulp in preparation of medicaments for menstrual period health care, and a pharmaceutical composition for menstrual period health care, wherein the pharmaceutical composition comprises an effective amount of compound donkey-hide gelatin pulp with respect to health care, and pharmaceutically acceptable carriers. A large number of experiments find that compound donkey-hide gelatin pulp has obvious blood-enriching effect on mice with blood deficiency due to blood loss, has certain inhibition effect on contraction of rabbit uterine smooth muscle, has obvious inhibition effect on rabbit in-vivo uterine smooth muscle spasm caused by pitocin, can alleviate excess contraction of rabbit uterine smooth muscle, has obvious alleviation effect on rat dysmenorrhea response caused by pitocin, can prolong the response latency, can significantly prolong the latency of rat dysmenorrhea spasm caused by pitocin, can reduce the frequency of body torsion, has significant analgesic effect, can obviously reduce rat blood viscosity, has certain blood circulation invigorating effect, and can relieve blood property change such as viscous, thick, coagulated blood of blood-stasis model rats.

The invention provides a Chinese herbal medicine effective for wound healing, namely, loropetalum chinense leaf composition. The loropetalum chinense leaf composition contains 11 total phenolic acidsand 15 total flavonoids. Animal experiments confirm that the composition derived from loropetalum chinense leaves has a good effect on wound healing. The loropetalum chinense leaves are planted and managed standardly in Jiangxi, and the source of the medicinal material is guaranteed. According to the loropetalum chinense composition, an extraction method is simple, operation is easy, and application range is wide. A basis for further medicinal development of the loropetalum chinense leaves is provided.

The invention discloses a pharmaceutical composition for treating irritable bowel syndrome, which consists of two raw materials of tangerine peel oil extracted from tangerine peel and clove oil extracted from clove and is mainly used for treating diarrhea type irritable bowel syndrome. The pharmaceutical composition can decrease intestinal tonicity and defecation frequency and improve feces texture and has the effects of being anti-inflammatory and antiseptic and adjusting gastrointestinal hormone and neuropeptide.

The invention relates to a pharmaceutical composition for treating hemorrhoid and process for preparation, wherein the composition comprises pagodatree fruit 385.5g, red peony root 193g, bark of peony root 193g, ledebouriella root 193g, Chinese angelica root 193g, bitter orange 193g, baikal skullcap root 193g and processed radix aconiti 8g.

The invention relates to a traditional Chinese medicine composition for treating lower abdominal discomfort, and a preparation method and a pharmaceutical use thereof. Furthermore, the invention relates to a traditional Chinese medicine composition for treating lower abdominal swelling pain, diarrhea, sickness and / or dysmenorrhea, as well as a preparation method and a pharmaceutical use thereof. The pharmaceutical composition provided by the invention contains raw materials such as anisetree bark, fructus evodiae, cinnamon, Chinese wampee seed, piper cubeba and the like. The traditional Chinese medicine composition is externally applied; and the traditional Chinese medicine composition is capable of effectively treating lower abdominal swelling pain, diarrhea, sickness and / or dysmenorrhea through clinical verifications. Besides, the medicinal materials have mutual obvious synergetic compatibility effect.

The gastropathy treating medicine is prepared with atractylodes rhizome, magnolia bark, banksias rose, fingered citron, white peony root, amomum fruit and pinellia tuber in certain weight proportion and through conventional preparation process. The pharmacodynamics experiments show that the medicine of the present invention can suppress the ear swelling of mouse caused by xylene, raise the pain threshold of mouse in hot plate process and reduce the twist times of mouse caused by acetic acid, and prove the antiphlogistic effect and analgetic effect of the medicine.

The invention relates to a traditional Chinese medicine extract composition, its preparation method and its application. The composition is composed of extracts respectively obtained from Corydalis Corydalis and Radix Angelicae Radix. The composition can be used to treat and / or prevent various diseases and depressions caused by qi stagnation and blood stasis, and has the characteristics of safety, effectiveness, controllability and the like.

The oral medicine for treat hysteromyoma is Chinese medicine preparation prepared with ten kinds of Chinese medicinal materials, including red peony root, Chuanxiong rhizome, peach kernel, cattail pollen, burred tuber, etc in certain weight proportion. The pharmacodynamics experiment on model mouse hysteromyoma and model rat hysteromyoma shows that the oral medicine can inhibit mouse hysteromyoma and rat hysteromyoma, improve the hestopathologic abnormality of the model mouse and rat, inhibit the uteritis of model rat, inhibit xylene caused auricle swelling of moue, reduce acetic acid caused twisting number of mouse, and shorten the bleeding time of tail breaking mouse. The animal experiment proves the functions of inhibiting hysteromyoma, resisting inflammation, relieving pain and arresting bleeding of the medicine, and medicine may be put in clinical test.

A dispersing tablet of Paris petiolata's saponin for treating metrorrhagia, metrostaxis, menorrhagia and poor uterine contraction is proportionally prepared from Paris petiolata's saponin, disintegrant, hydrophilic agent, adhesive and cosolvent.

The invention discloses a method for researching analgesic and anti-inflammation effects of fallopia aubertii. The method comprises the following steps: 1, influence on mouse pain caused by thermal stimulus; 2, influence on mouse pain caused by chemical stimulus; 3, an experiment of mouse auricular swelling caused by xylene; 4, an experiment of metatarsal swelling caused by egg white; and 5, a statistical method. Foundation is laid for research on the analgesic and anti-inflammation effects of the fallopia aubertii.

The invention relates to a Chinese medicinal tea bag for treating acute and chronic pharyngitis and its production method, which comprises the following raw materials (by weight portions), dyers woad leaf 340-360 parts, honeysuckle flower 340-360 parts, dried tangerine fibres 340-360 parts, sterculia seed 200-220 part, ophiopogon root 340-360 parts, bamboo leaf 340-360 parts, green tea 200-220 parts.

The invention discloses nursing medicine liquid for treating burns and scalds and a method for preparing the nursing medicine liquid. The nursing medicine liquid comprises Chinese and western medicine components including, by weight, 50-80 parts of white sesame oil, 4-10 parts of nacre mother of pearl, 2-12 parts of lithospermum purpurocaeruleum, 2-9 parts of borneol, 5-10 parts of common bletilla pseudobulb, 10-15 parts of sanguisorba officinalis, 20-25 parts of rhubarb, 5-15 parts of angelica sinensis, 8-12 parts of radix sophorae subprostratae, 10-15 parts of rhizoma paridis, 15-20 parts of fructus cnidii, 5-10 parts of fructus kochiae, 12-15 parts of honeysuckle, 5-10 parts of white cinnamon, 5-8 parts of peppermint, 5-10 parts of radix ampelopsis, 5-8 parts of panax notoginseng, 5-8 parts of pearl powder, 0.3-0.5 part of honey, 0.1-0.2 part of chlorhexidine acetate, 0.1-0.2 part of miconazole nitrate, 0.2-0.5 part of amoxicillin, 0.1-0.2 part of cefalexin and 0.2-0.5 part of furazolidone powder. The nursing medicine liquid and the method have the advantages that the nursing medicine liquid can be easily and feasibly prepared and is low in cost; the nursing medicine liquid has few side effects and is inexpensive, and the burns and scalds can be effectively treated by the aid of the nursing medicine liquid.

The invention relates to a medical composition for treating liver disease (that is shu gan shun Qi medical composition) and a preparation method thereof. The medical composition is prepared from 13 crude drugs including Magnolia officinalis, Rhizoma Chuanxiong, Nutgrass Galingale Rhizome, White Peony Root, Chinese Thorowax Root, Fructus Aurantii Immaturus, Aiomatic Turmeric Root-tuber, Fructus Citri Sarcodactylis, Radix Aucklangiae, dried orange peel, licorice, Rhizoma Corydalis Yanhusuo, Kalimeris indica; the basic preparation method comprises the following steps: grinding the raw medicines into fine powder, uniformly mixing the powder, then adding pharmaceutical excipients for uniform mixing, and drying the mixture to obtain the formulation needed. Partial medicinal materials in the composition contain volatile substances, so the invention adopts the steps of firstly crushing 2 / 3 of the raw materials, and then crushing the remaining 1 / 3 of the crude drugs, performing reflux extraction and then decocting to fully utilize effective ingredients, the medicine can be absorbed completely and the medicine efficiency is enhanced. The raw material ratio is screened in a scientific way, and the composition has the effect of smoothing liver, regulating vital energy and alleviating pain, can be used for treating liver depression and qi stagnation symptoms such as rib tumescence, stomach hurt, vomit against the noisy, and belching to realize address both the symptoms and root causes.

The present invention discloses a pharmaceutical preparation for treatment of purulent sinusitis and a preparation method thereof, and in particular relates to the use of a traditional Chinese medicine compound prescription for treatment of purulent sinusitis. The pharmaceutical preparation is prepared from houttuynia and patrinia and the like as raw materials for distillation, boiling, concentration, alcohol precipitation, and the like to obtain a clear paste. The product pharmaceutical preparation is produced at room temperature, energy consumption is reduced; production equipment is simple, operation is easy; production process step is innovative; ethanol, distilled water, and other toxic substances are mainly used in the production process, and can be recycled after use; material resources can be safely and fully used in production, no ''three wastes'' is discharges, production cost is low, and the production method is energy saving. The pharmaceutical preparation prepared by the method can be widely used in medicine, health and other industries.

The invention relates to the technical field of medicines, and discloses a needle and medicine integrated hydrogel microneedle. A microneedle matrix is hydrogel formed by a gelatin and tannic acid cross-linked product, a drug is entrapped in the matrix, and the drug is a cinnamon oil nanocapsule. The cinnamon oil nanocapsule hydrogel microneedle (HFMNs-CIOs-NCs) can better entrap cinnamon oil nanocapsules (CIOs-NCs) and deliver the CIOs-NCs to the deep layer of the skin in the acupoint region, the effect of warming the middle-jiao for dispelling cold of cinnamon oil is fully played, meanwhile, the microneedle absorbs water to swell, the tissue in the Shenque acupoint region can be stimulated, the acupoint region effect is stimulated, and the effect of the CIOs-NCs in the acupoint region is stimulated. The cold coagulation symptom of a cold coagulation and blood stasis type dysmenorrhea model rat is improved. The needle-medicine integrated hydrogel microneedle can be used for various entrapment medicines and preparations thereof, is further used for clinical treatment of acupoint therapy, and has clinical popularization and use values.

The invention discloses an anti-inflammatory and analgesic medicine composition and an application thereof. The medicine composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 20-40 parts of purpleflower holly leaves and 60-100 parts of tangerine leaves. The medicine composition has the significant effects of inflammatory prevention and analgesia and good clinical significance, and is free of immunosuppression and low in toxic and side effects.

The invention relates to a traditional Chinese medicine preparation used for curing hemorrhoids and a preparation method thereof. The preparation is made from the active drug ingredients processed by dioscorea rhipogomoides, pod of pagodatree, cassia seed, oyster (calcined), ginseng, subprostrate sophora and honeysuckle and a pharmaceutically acceptable carrier according to a certain proportion by processing. The carrier is starch. Compared with the prior art, the traditional Chinese medicine preparation provided by the invention has obvious curative effects when being used for treating internal hemorrhoids of phase I and phase II.

The invention discloses a veterinary-use radix daphniphylli calycini and red-knees herb granule and application thereof to chicken necrotic enteritis. The radix daphniphylli calycini and red-knees herb granule is prepared from radix daphniphylli calycini, red-knees herb and auxiliary materials, wherein the active ingredients of the radix daphniphylli calycinum and the red-knees herb in the radix daphniphylli calycini and red-knees herb granule are radix daphniphylli calycini and red-knees herb extracts obtained through performing reduced pressure concentration and vacuum drying on the radix daphniphylli calycini and red-knees herb alcohol extraction liquid; the auxiliary materials are a mixture of dextrin and saccharose. The alcohol extraction process of the radix daphniphylli calycini and red-knees herb is optimized; under the optimum process conditions, 33.01+ / -0.30mg / g of general flavone, 271.31+ / -0.37 mug / g of quercetin and 23.16+ / -0.47 percent of extraction rate can be realized. Through the study, the analgesic effect of the radix daphniphylli calycini and red-knees herb granule on the nervus centralis is a little weaker than the analgesic effect on peripheral nerves; the effusion of early-stage inflammatory tissue fluid can be effectively reduced; the dose-effect relationship is shown, i.e., the inhibition rate is higher when the dose is greater; when the granule is combined with antibiotics, the chicken necrotic enteritis can be effectively prevented and treated.

The invention relates to traditional Chinese medicinal liquor for treating hyperostosis and a preparation method of the traditional Chinese medicinal liquor. The traditional Chinese medicine composition consists of the following raw materials according to a certain weight ratio: hoya lancilimba, twitch-grass leaves, pterospermum grande craib, climacium dendroides, root of rosthorn bigginseng, litsea cubeba, root of tube clematis, phyllanthus reticulata, pearly maesa, phlegmariurus hamiltonii, herb of glabrous sarcandra, polypodium hymenodes kunze, marsdenia longipes, polygonum amplexicaule, flos pyrethri tatsienensis, procris laevigata, elatostema stewardii merr, silene baccifera, cissus assamica craib, herb of japanese saussurea, herb of scape-like sage, euonymus chinensis Lindl, mistletoe and bulbil. The traditional Chinese medicinal liquor is researched on the basis of dialectical therapy of the traditional Chinese medicine according to the clinical tests and has functions for dispelling the wind, eliminating the dampness, promoting blood circulation to remove meridian obstruction, eliminating the stagnant blood, alleviating the pain, tonifying the liver and kidney and strengthening the bones. The traditional Chinese medicinal liquor has the advantages that the clinical healing rate is high, safety, convenience, non-toxicity and no side effect.

The invention provides application of duramen of Acanthopanax giraldii Harms or extract of the duramen of Acanthopanax giraldii Harms. The duramen of Acanthopanax giraldii Harms or the extract of the duramen of Acanthopanax giraldii Harms is capable of evidently prolonging response latency of mouse writhing reaction and reducing mouse writhing frequency and has a remarkable analgesic efficacy, and the analgesic effect of a low-dose group is superior to that of a high-dose group and is equivalent to that of indometacin which is a classical analgesic medicine. By utilization of duramen, which is conventionally abandoned as a non-medicinal part, of Acanthopanax giraldii Harms, comprehensive development and protection of medicinal resources of Acanthopanax giraldii Harms are significantly promoted, and promising market prospect is realized.