Veterinary-use radix daphniphylli calycini and red-knees herb granule and application thereof to chicken necrotic enteritis

Abstract

The invention discloses a veterinary-use radix daphniphylli calycini and red-knees herb granule and application thereof to chicken necrotic enteritis. The radix daphniphylli calycini and red-knees herb granule is prepared from radix daphniphylli calycini, red-knees herb and auxiliary materials, wherein the active ingredients of the radix daphniphylli calycinum and the red-knees herb in the radix daphniphylli calycini and red-knees herb granule are radix daphniphylli calycini and red-knees herb extracts obtained through performing reduced pressure concentration and vacuum drying on the radix daphniphylli calycini and red-knees herb alcohol extraction liquid; the auxiliary materials are a mixture of dextrin and saccharose. The alcohol extraction process of the radix daphniphylli calycini and red-knees herb is optimized; under the optimum process conditions, 33.01+ / -0.30mg / g of general flavone, 271.31+ / -0.37 mug / g of quercetin and 23.16+ / -0.47 percent of extraction rate can be realized. Through the study, the analgesic effect of the radix daphniphylli calycini and red-knees herb granule on the nervus centralis is a little weaker than the analgesic effect on peripheral nerves; the effusion of early-stage inflammatory tissue fluid can be effectively reduced; the dose-effect relationship is shown, i.e., the inhibition rate is higher when the dose is greater; when the granule is combined with antibiotics, the chicken necrotic enteritis can be effectively prevented and treated.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a veterinary Fengyao granule and its application in chicken necrotic enteritis. Background technique [0002] Acute and chronic gastroenteritis is a common and frequently-occurring disease. Clinically, abdominal discomfort, abdominal pain, nausea and vomiting, abdominal distension and diarrhea, belching and pantothenic acid, and loss of appetite are the main clinical manifestations. The cause of the disease is often overeating and unclean diet Due to history. It has been found in clinical medicine that the Fengyao preparation composed of Niuerfeng and Cape Polygonum has the functions of regulating qi, invigorating the stomach, dehumidification and stagnation, and is used for acute gastroenteritis and abdominal distension caused by unhealthy middle movement, stagnation of qi and dampness. , abdominal pain and diarrhea and other dyspepsia, clinically achieved good re...

AI Technical Summary

Problems solved by technology

[0016] Some people in the industry said that human medicine has not been tested on animals, including dosage and safety tests. If human medicine is used for veterinary use, the dose is not accurate, and there is a great potential safety hazard

In addition, human antibiotics accumulated in animals will be excreted into the environment in the form of prototype or metabolites through feces, polluting water and soil, thus causing the threat of "drug-resistant bacteria" in water and soil, and further harming the human body

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