The invention relates to an anti-pilling treatment method for a light and thin wool-polyester fabric. The method comprises the following steps: weaving wool-polyester yarns, wherein the wool content of the yarns is 20-99%, and the yarns are 12.5-19.23tex; boiling the woven fabric, dehydrating, scotching, performing wool fabric scouring, washing, dehydrating, putting into microwave drying shaping-low-temperature normal-pressure plasma treatment equipment, performing microwave drying shaping firstly, and performing low-temperature normal-pressure plasma treatment secondly; finally performing softening finishing, so as to obtain the light and thin wool-polyester fabric. Microwave heating of the method has the advantages of high efficiency, energy conservation, low temperatures, uniform drying, no thermal inertia, and the like; industrial production of magnetrons is already achieved, so that the equipment is convenient to repair and replace and low in maintenance cost; by using a low-temperature normal-pressure plasma treatment technique, surface modification treatment on wool fibers in the fabric is implemented through medium baffled power discharge, so that the amounts of chemical reagents and water in the after finishing process of a woolen fabric are reduced, the energy is saved, the environment is protected, and the anti-pilling property of the fabric is improved.