32results about How to "Large amount of product" patented technology

The invention provides a method for preparing a steroid drug intermediate employing bioconversion phytosterol. The method comprises the following steps: 1) providing turbid liquid of phytosterol; 2) providing a resting cell of a microbial strain for converting the phytosterol into a steroid drug intermediate; 3) mixing the turbid liquid of the phytosterol with the resting cell, and adding beta-cyclodextrin or chemically modified beta-cyclodextrin to evenly mix, and cultivating to finish conversion; 4) centrifuging the conversion liquid obtained in the step 3), separating supernatant from thallus, separating to obtain the steroid drug intermediate from the supernatant by solvent extraction. By adopting the method provided by the invention, the sterol feeding concentration is improved, the target product quantity is increased, simple separation of the thallus, a cosolvent and a product is achieved when the conversion lasting time is shortened, repeated use of the thallus and the cosolvent for a plurality of times is achieved, the production cost is greatly saved, and the method is applicable to industrial production.

The invention discloses an application of heat-resisting beta-glucosidase mutants N223T, G224F and N223T / G224F to transforming arctiin into arctigenin. Amino acid sequences of the heat-resisting beta-glucosidase mutants N223T, G224F and N223T / G224F are indicated in SEQ: ID NO.1, ID NO.2 and ID NO.3. The arctiin is hydrolyzed to prepare the arctigenin by the aid of heat-resisting beta-glucosidase and the mutants thereof, and as compared with wild-type enzyme, the heat-resisting beta-glucosidase has the advantages of high transformation efficiency, fewer reaction by-products, high yield and purity, easiness in separation and purification, less chemical pollution and the like.

The invention discloses a preparation method for a two-dimensional supported nanometer magnesium hydride hydrogen storage material. The preparation method comprises the following steps of (1) by taking a magnesium metal-contained organic compound and graphene as raw materials, under argon shield, performing ball milling at a room temperature and a hydrogen atmosphere, and performing hydrogenationon the magnesium metal-contained organic compound to obtain suspension liquid of graphene supported magnesium hydride as a reaction product; and (2) performing suction filtration and drying on the obtained reaction product to obtain the two-dimensional supported nanometer magnesium hydride hydrogen storage material. The preparation method provided by the invention has the advantages of reduced cost, simplified synthetic method, simple technological process, high production efficiency, low energy consumption, high process safety and relatively large yield; and in addition, the two-dimensional supported nanometer magnesium hydride prepared by the preparation method has high hydrogen storage capacity and excellent cycling stability, has very large potential on the aspects of hydrogen storageand conveying, fuel cells and the like and is a hydrogen storage material with great application prospect.

The invention provides a preparation method of MoS2 micro-nanospheres with a hierarchical structure, and relates to the technical field of preparation of micro-nanostructured materials. The MoS2 micro-nanospheres with the hierarchical structure are prepared through a hydrothermal reaction, an S source and a Mo source are added to a PAM (polyacrylamide) aqueous solution at the room temperature andstirred uniformly, and a reaction precursor solution is obtained; the reaction precursor solution is transferred into a reaction kettle and subjected to the hydrothermal reaction, and the MoS2 micro-nanostructured material can be obtained. According to the preparation method, the MoS2 micro-nanospheres with the hierarchical structure are successfully prepared from thioacetamide or thiourea as theS source, sodium molybdate or ammonium molybdate as the Mo source and a PAM template control agent with a simple hydrothermal method. Shaping of the MoS2 particles is realized, and one new method is provided for preparation of the MoS2 material with the hierarchical structure. The preparation method is simple to operate and low in cost, and the yield of obtained products is high.