The invention discloses a virtual machine cloning method and device, equipment and a medium. The method comprises the steps of obtaining a virtual machine cloning instruction; according to the virtualmachine cloning instruction, starting a card I / O tool used for forbidding issuing a writing instruction so as to control a to-be-cloned target virtual machine not to perform writing operation; snapshooting the target virtual machine to obtain a target snapshot; and cloning the target snapshot to obtain a cloned virtual machine. Visibly, according to the method, after obtaining a virtual machine cloning instruction, a card I / O tool is started according to the virtual machine cloning instruction; therefore, the target virtual machine to be cloned is controlled not to perform write operation; then, snapshotting is carried out on the target virtual machine; after the target snapshot is obtained, the target snapshot is cloned to obtain the cloned virtual machine, so that the cloning of all thevirtual machines to be cloned can be completed at one time under the condition of no shutdown, the time is saved, the cloning efficiency is high, and the data consistency of the obtained cloned virtual machine can be ensured through snapshot printing.