The invention relates to a formula and a preparation process of a five-cereal free food capable of resisting hunger and thirst, preserving health and prolonging service life, belonging to the field of the formula of food. The food comprises the following components: sorghum, corn, coix seeds, cattail pollen, pine pollen, buckwheat pollen, lotus pollen, flos sophorae pollen, walnut kernels, walnut kernels, fructus cannabis, polygonatum, rice bean, red bean, black dates, sweet-scented osmanthus, black tea, boschniakia rossica, tacca chantrieri, lycopodium fargesii, cordyceps, saffron, Chinese yam, tuckahoe, ganoderma lucidum, malt, ophiopogon japonicus, astragalus, fried gecko, fried earthworm, processed manis pentadactyla, pseudo-ginseng flowers, ginseng flowers and black sesame. The preparation process of the food comprises the steps mixing the components and grinding into fine powder or superfine powder. The food can take good effect on the mental, physical, spiritual and disease treating aspects of people. The formula and the preparation process of the food are simple and convenient to use.