The invention discloses a medicine storage cabinet realizing management based on the internet of things technology, and belongs to the field of medicine storage cabinets. For the medicine storage cabinet realizing management based on the internet of things technology, by controlling a master control operation panel, information inquiry can be carried out on medicines in a plurality of storage cavities, after inquiry, the medicine information can be synchronously displayed on medicine information display screens on the outer sides of sealing windows, information management and inquiry can be carried out on the medicines in real time, meanwhile, a temperature sensor and a weighing table are arranged in each storage cavity, so that real-time monitoring can be carried out on the weight of themedicines and the temperature of the environment of the medicines, when the monitoring shows that the weight of the medicines is insufficient, an operator is reminded to timely supplement the medicines, while when the temperature control is improper, through a temperature control device on the back of a cabinet body, the temperatures in the storage cavities can be independently or synchronously set and controlled timely and effectively, and therefore, the intelligent storage of the medicines is effectively realized.