316results about How to "Improve pregnancy rate" patented technology

The invention provides a cow feedstuff combination, in particular to a functional feedstuff combination to feed high production cow. The invention endows fatty acid with function of rumen passing by adding strong alkali week acid salt fatty acid salt, to act as energy supplement agent for cow; the combination is matched with other protein feedstuff, energy feedstuff, mineral, Vitamin and so on to acquire a fine mixture, which can meet the special requirement of such components as energy, protein, Vitamin and mineral and so on of cow, in particular to high production cow 100 days after delivery, and release the energy balance, improve the body condition, milk quality and anti-stress, and prevent the occurrence of nutrition metabolization diseases.

The subject invention provides methods for improving livestock health. In specific embodiments, the invention provides methods for accelerating and / or augmenting livestock growth; improving immunity; and enhancing fertility in livestock. To do so, the present invention provides materials and methods for administering a cysteamine compound to livestock.

The present invention provides a method for enhancing embryo viability comprising administering at least one inhibitor of p53 or a p53-associated pathway to one or more of the following: the embryo, oocytes, sperm, a femme animal or a male animal.

The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and / or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.

The invention provides a protocol leading to improved embryo implantation rates and / or decreased miscarriage rates in which hCG, or a bio-analogue, is administered during the follicular phase.

Instead of immersing human reproductive cells in a single culture medium throughout the various procedures used in IVF, a process is provided by which the reproductive cells may be moved through a sequence of distinct culture media as the various IVF procedures are carried out. In one implementation, the culture media specifically formulated to provide a physical environment similar to that found within the female reproductive tract and conducive to growth and development of human reproductive cells during the various stages of the IVF process. In this regard, specifically formulated culture media can be applied to support the reproductive cells in one or more of the following procedures: oocyte retrieval and handling; oocyte maturation; ordinary fertilization; oocyte, zygote and embryo examination and biopsy; embryonic development to the eight-cell stage; embryonic development to the blastocyst stage; embryo transfer; and cryopreservation.

The invention discloses a bamboo rat breeding method. The method includes the following steps of young rat feeding and hybridization, wherein in the step of young rat feeding, young rats after ablactation are put into a cultivation pond to be fed in a gregarious mode, female rats and male rats are kept together, and after being pregnant, the female rats are separately kept; in the step of hybridization, after the female rats produce young rats and the young rats are ablactated, the female rats are kept separately, each female rat can mate with multiple male rats, and the male rats are replaced once every other two to seven days until the corresponding female rat is pregnant. The young rats are kept in a grouped mode, 15-20 young rats constitute a group, all groups are combined every other fifteen to twenty days, and the young rats are regrouped. According to the bamboo rat breeding method, the bamboo rats can be cultivated to be docile, one female rat can mate with multiple male rats, and accordingly the breeding rate of the bamboo rats is improved; the bamboo rats are kept through fishscale bamboo, so that the physique of the bamboo rats is improved and the breeding rate is improved.

The subject invention provides methods for improving livestock health. In specific embodiments, the invention provides methods for accelerating and / or augmenting livestock growth; improving immunity; and enhancing fertility in livestock. To do so, the present invention provides materials and methods for administering a cysteamine compound to livestock.

The invention relates to a preparation for treating female sterility, in particular to a Chinese medicinal preparation for treating female sterility caused by salpingemphraxis. The Chinese medicinal preparation mainly adopts Chinese medicines by certain weight portion, such as pangolin, pseudo-ginseng, frankincense, safflower, hemlock parsley, peach kernel, rhizoma zedoariae and the like, to play the functions of sterilizing and diminishing inflammation, eliminating stasis to resolve swelling, circulating blood and dissipating stagnation, regulating the menstruation and dispersing ruffian, removing retention and circulating vital energy, dredging and lubricating the intestines on salpinx chronic inflammation, conglutination, hydrops and obstructive obstruction. Compared with the traditional treatment method, the Chinese medicinal prepration has the advantages of treating both principal and secondary aspect of disease without any pain or side effect on a patient with accurate healing efficacy on clinical tests, and significantly improving the cure rate and pregnancy rate after healing.

The present invention relates generally to the fields of reproductive medicine. More specifically, the present invention relates to a method determining the developmental stage of human cumulus cells issues from MII oocyte.

In the preferred embodiment, bovine semen is mixed with a suitable solution to form an insemination medium which is injected into the reproductive organs of a female bovine to flood the uterine horns in a nonsurgical AI procedure. The invention includes an AI instrument having a disposable, single use pipette that may be used with this nonsurgical procedure. The AI instrument does not include a balloon and is referred to as “catheter free”. Preferably, the uterine horns are flooded concurrently, but in the alternative, they may be flooded sequentially.

The invention discloses a medicinal composition, which comprises Chinese medicinal materials 30-99.9% of the total weight of the composition, and pharmaceutically acceptable carries in balancing amount. The Chinese medicinal materials include the following Chinese traditional medicines by weight: (a) 15-90 parts of Chinese medicinal materials for providing sperms motion energy, (b) 15-60 parts of Chinese medicinal materials for strengthening adenosine triphosphate, (c) 70-330 parts of Chinese medicinal materials for providing antioxidation effect, (d) 10-50 parts of Chinese medicinal materials for promoting sperms generation, (e) 10-40 parts of Chinese medicinal materials for regulating internal secretion, and (f) 20-80 parts of Chinese medicinal materials for invigorating qi and strengthening spleen. The invention also discloses a preparation method and an application thereof.

The invention relates to an antifreeze agent for diluting pig sperm, pertaining to the technical field of animal breeding. The antifreeze agent is prepared by N-acetyl-D-dextrosamine, hyaluronic acid, amido-sodium-lauryl sulfuric ester, glucose, trihydroxymethyl aminomethane, sodium citrate, sodium bicarbonate, potassium chloride, bactericide, distilled water and the like, wherein, the N-acetyl-D-dextrosamine can stimulate the emulsification function of the amido-sodium-lauryl sulfuric ester, enhances the protection function of the amido-sodium-lauryl sulfuric ester and yolk, the hyaluronic acid and the amido-sodium-lauryl sulfuric ester can effectively inhibit the damage rate of freezing and thawing sperm plasma membrane and DNA and improve the quality of freezing and thawing sperm, the glucose is the energy source for metabolism in vitro of the sperm, and the sodium citrate can maintain the osmotic pressure balance between diluted antifreeze agent environment and the internal environment of the sperm. The antifreeze agent for diluting pig sperm can effectively prolong the survival time of pig sperms for ultra-low temperature cryopreservation, and improve the liveliness of the freezing and thawing pig sperms, the integrity of plasma membrane and the integrity of acrosome.

The invention discloses a rocking dynamic culture box. The rocking dynamic culture box comprises a box body, a sliding groove, a motor, a reciprocating motion mechanism and a motor speed adjusting device, wherein a tray is arranged in the box body; the sliding groove is formed below the tray; a sliding block matched with the sliding groove is arranged at the bottom of the tray and connected with the sliding groove in a sliding way; the sliding groove is supported by a bracket; the reciprocating motion mechanism comprises a crank and a connecting rod; one end of the connecting rod is connected with the sliding block; the other end of the connecting rod is connected with an output shaft of the motor through the crank; the motor drives the crank to rotate and pushes the sliding block to reciprocate in the sliding groove through the connecting rod; and the motor speed adjusting device is connected with the motor. According to the rocking dynamic culture box, the crank and connecting rod mechanism is driven by the motor to drive the tray to reciprocate with a low frequency in a small range, so that an oocyte or embryo for in-vitro culture is positioned in a dynamic culture environment, so as to simulate the rocking state of the oocyte or embryo in uterus. Therefore, the embryo development quality can be remarkably promoted and the later embryo implantation can be promoted, so as to increase the pregnancy rate.

The present invention is directed at substituted heteroaryl and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and / or high levels of LDL-cholesterol and triglycerides such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.

The invention provides a sperm screening and in vitro fertilization bionic device based on micro fluidic technology. The sperm screening and in vitro fertilization bionic device based on micro fluidic technology comprises a bionic device main body; the bionic device main body is composed of a glass sheet layer, a silica gel pipeline layer, and a polydimethylsiloxane layer; a center cell is arranged at the middle part of the silica gel pipeline layer; an inlet cell, a first outlet cell, and a second outlet cell are arranged outside the center cell; the center cell is communicated with the inlet cell, the first outlet cell, and the second outlet cell via a first pipeline, a second pipeline, and a third pipeline respectively; the first pipeline is provided with a first sample adding port; the second pipeline is provided with a second sample adding port; and the third pipeline is provided with a third sample adding port. The sperm screening and in vitro fertilization bionic device is used for stimulating complete natural impregnation process, unfavorable influences of operation on gametes and embryos are avoided, and polyspermy is avoided; high quality embryos at stimulated natural impregnation states can be obtained, in vitro fertilization success rate is increased greatly, the potential causes of sterility can be identified, and a direction is provided for clinical treatment.

The invention provides a method for inducing a high-yield dairy cow to regularly ovulate and increasing the conception rate. The method includes the steps that 1, 35-40 days after the high-yield dairy cows calve, a progestational hormone device is embedded into a dairy cow vagina for the first time; 2, the progestational hormone device is taken out after being embedded for 14-16 days; 3, prostaglandin is injected; 4, 2 days after the prostaglandin is injected, an ovulation promoting hormone is injected; 5, 12-16 hours after the ovulation promoting hormone is injected, artificial insemination is carried out; 6, on the sixth to eighth day after artificial insemination, the progestational hormone device is embedded again, and the further embedding time ranges from 14-16 days. According to the method, the development and ovulation time of follicles in the ovary of the dairy cow can be regulated, detection of oestrus is not needed, artificial insemination is directly carried out, fetus protection medicine is adopted, and the survival rate of embryos is increased. The defects that oestrus of the high-yield dairy cow is not easy to observe is overcome, the oestrus rate and the conception rate of the dairy cow can be increased, the calving interval of the high-yield dairy cow is shortened, breeding benefits of the high-yield dairy cow are increased, and production management of a dairy cow farm is convenient.

The invention relates to a pharmaceutical composition for treating endometriosis, which is prepared from Chinese medicinal herbs including astragalus root, cattail pollen, trogopterus dung, leeches, wood louse, frankincense, zedoary, rhubarb, centipede, epimeddium, morinda root and Chinese angelica root.

The invention relates to an intelligent system and control method for animal body temperature acquisition and estrus monitoring. The intelligent system for animal body temperature acquisition and estrus monitoring comprises an intelligent body temperature acquisition and RFID device, an acquisition base station, a background server and a estrus monitoring station; the intelligent body temperatureacquisition and RFID device includes a high-sensitivity internal body temperature sensor module, a high-sensitivity shell temperature sensor module, a single-chip microcomputer module, a built-in battery module and a wireless communication module; the high-sensitivity internal body temperature sensor module and the high-sensitivity shell temperature sensor transmit ADC data to the single-chip microcomputer module; the single-chip microcomputer module transmits processed data to the acquisition base station through a wireless transmission protocol; the acquisition base station actively reportsthe data to the background server; and a user can conveniently grasp the body temperature condition of an animal through a mobile phone or a computer. With the intelligent system and control method ofthe invention adopted, animal farm management staff can grasp the temperature of each animal, whether the animals are in estruses, and other conditions timely and easily, so that the staff can isolate and treat animals that may have problems in advance; animals in estruses can be know according to data, so that the chance of conception of the animals can be improved, and therefore, the efficiencyof a breeding plant can be improved.

The present invention is directed at substituted heteroaryl- and phenylsulfamoyl compounds, pharmaceutical compositions containing such compounds and the use of such compounds as peroxisome proliferator activator receptor (PPAR) agonists. PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and / or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans. The compounds are also useful for the treatment of negative energy balance (NEB) and associated diseases in ruminants.

The invention provides a protocol leading to improved embryo implantation rates and / or decreased miscarriage rates in which hCG or LH, or a bio-analogue thereof, is administered during the follicular phase.

The invention discloses a breeding method for a sow in a reproduction period. The method comprises the following steps: feeding in a reserve period, feeding in a pregnancy period, and feeding in a lactation period. According to the invention, directed at actual states of the sow in all stages of the reproduction period, targeted feeding with a feed with different components and proportions is economic, scientific and reasonable, and fully meets the requirements of the sow for nutrients in all stages at the same time, so the sow can remain a good growth state from oestrum to piglet delactation, i.e., the sow in an oestrous period has the advantages of well-developed, high-quality and numerous ova, high pregnancy rate, high survival rate of fertilized ova, high survival rate of early embryos in the early stage of mating, good developmental state of metaphase embryos, and high survival rates of the piglets after birth and in the lactation period; thus, the marketing rate of commercial pigs is fundamentally increased, and pig-raising efficiency is improved.

The invention discloses a cultivation method of breeding sows and belongs to the field of cultivation methods of the breeding sows. The cultivation method includes the steps of firstly, controlling temperature and humidity; secondly, feeding; thirdly, selecting a boar, inducing oestrus, and checking and judging oestrus states; fourthly, mating, to be more specific, performing artificial insemination, stimulating during the artificial insemination, and stimulating after mating. The cultivation method has the advantages that the pig house environments, feeding, oestrus inducing and the whole mating process of to-be-inseminated sows are controlled and managed systematically, the humanized insemination measure simulating natural insemination is used, and the insemination rate and parturition rate are increased.

A reduced dose inseminate and method for producing and using such reduced dose inseminate to fertilize the eggs of a female animal by artificial insemination with fewer sperm cells than compared with conventional dose inseminates.

The invention provides an animal model with male reproductive disorders of a non-human mammalian animal, as well as a preparation method and application of the animal model, and further identifies the functions of a Prss37 gene and a protein. The Prss37 gene of the animal model is inactivated, thereby affecting the appearance of ADAM3 in mature sperms produced by the animal model, indirectly affecting the combination of the sperms-zona pellucida and the migration of the sperms from the uterus to the oviduct and resulting in the serious male reproductive disorders. The model, the Prss37 gene and the protein thereof can be used for screening ADAM3 ripening accelerators, as well as sterility infertility treatment agents or contraceptive medicaments.

A semen diluent of blue for is prepared from N-acetyl-D-glucosamine, fructose, sodium citrate trihydroxylmethyl amonomethane, buffer, bacteriacide and distilled water. The diluent pH value is 6.20-6.80 and its osmotic pressure is 300-350 mOsmol / L.

The invention relates to a composite premix feed for foxes and raccoon dogs. The composite premix feed is applied to the field of fox and raccoon dog breeding or the field of fur animal feed production and is particularly used for improving the productivity of the foxes and the raccoon dogs. The composite premix feed comprises formulas for the growth period and the reproduction period. The formula mainly comprises multi-vitamin, blue copperas, baile copper, ferrous sulfate monohydrate, baile iron, zinc sulfate monohydrate, baile zinc, manganese sulfate monohydrate, baile manganese, potassium iodide, sodium selenite, aureomycin, choline, angel active dry yeast, angel composite yeast, calcium hydrophosphate and corn protein powder. Composite premix feed constituents and contents of the constituents for two key production stages, namely the growth period and the reproduction period, of the foxes and the raccoon dogs are researched; the growth performance of the foxes and the raccoon dogs is improved, and the reproduction performance of seed beast is improved.

The invention discloses a timely artificial insemination method for a giant panda. The method comprises the steps of: collecting, testing and analyzing urine samples of female giant pandas during oestrus in spring, simultaneously combining with these circumstances such as time that the drop of an estradiol maximal peak value or an estradiol peak value reaches up to over 50%, the condition whether a progesterone value is on the rise and the giant panda generates a typical heat peak behavior in the process of the estradiol dropping from the maximal peak value or subsequent peak value, and the ratio of the progesterone value corresponding to the estradiol maximal peak value or subsequent estradiol peak value to the progesterone basic value, judging a real peak value of the estradiol of the giant panda; then carrying out artificial insemination for the first time within 24-48 hours after the moment when the estradiol real peak value appears, and carrying out artificial insemination for the second time after 6-8 hours after finishing the artificial insemination for the second time, finally obviously improving the pregnancy rate of the giant panda. Compared with the past, the artificial insemination pregnancy rate of the giant panda is improved to 42.11% from 20.41% and is more than doubled.

The present invention relates to a novel label-free tomographic interferometry technique implemented inside an environmental chamber (e.g. imaging incubator) that provides rapid capturing of the three-dimensional (3-D) refractive index distribution of biological cells.