Rocking dynamic culture box

Abstract

The invention discloses a rocking dynamic culture box. The rocking dynamic culture box comprises a box body, a sliding groove, a motor, a reciprocating motion mechanism and a motor speed adjusting device, wherein a tray is arranged in the box body; the sliding groove is formed below the tray; a sliding block matched with the sliding groove is arranged at the bottom of the tray and connected with the sliding groove in a sliding way; the sliding groove is supported by a bracket; the reciprocating motion mechanism comprises a crank and a connecting rod; one end of the connecting rod is connected with the sliding block; the other end of the connecting rod is connected with an output shaft of the motor through the crank; the motor drives the crank to rotate and pushes the sliding block to reciprocate in the sliding groove through the connecting rod; and the motor speed adjusting device is connected with the motor. According to the rocking dynamic culture box, the crank and connecting rod mechanism is driven by the motor to drive the tray to reciprocate with a low frequency in a small range, so that an oocyte or embryo for in-vitro culture is positioned in a dynamic culture environment, so as to simulate the rocking state of the oocyte or embryo in uterus. Therefore, the embryo development quality can be remarkably promoted and the later embryo implantation can be promoted, so as to increase the pregnancy rate.

Description

technical field [0001] The invention relates to the field of biotechnology or reproductive medicine, in particular to an incubator capable of dynamically cultivating oocytes or embryos. Background technique [0002] In animal embryo engineering research or human assisted reproductive technology, in vitro maturation of oocytes, fertilization or in vitro culture of pre-implantation embryos is a routine operation in the laboratory, mainly carried out in an incubator. [0003] To improve the in vitro development quality of gametes or embryos, laboratory research mainly focuses on the optimization of medium components, addition of cytokines, appropriate oxygen concentration, etc. With the in-depth research of the laboratory research group, the in vitro culture system of embryos or gametes is becoming more and more perfect. Various culture conditions (gas phase, temperature) try to completely simulate the internal environment of the female reproductive system (uterus or fallopian ...

AI Technical Summary

Problems solved by technology

With the in-depth research of the laboratory research group, the in vitro culture system of embryos or gametes is becoming more and more perfect. Various culture conditions (gas phase, temperature) try to completely simulate the internal environment of the female reproductive system (uterus or fallopian tube), but it is different from the natural development of embryos in vivo. The embryo quality and implantation rate cannot be completely compared with that of the female reproductive tract because the embryonic development environment in the female reproductive tract is more complex, and the composition of the oviduct or uterine endocrine fluid is complex, which provides a perfect growth environment for embryonic development and implantation

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