390 results about "Miscarriage" patented technology

The present invention discloses a novel method of prevention of birth defects, miscarriages and infertility in women. The two therapies, disclosed herein, the hormone normalization therapy and the aromatase inhibitor-hormone normalization therapy, focus on restoring young hormonal levels in women in order to prevent female infertility and miscarriages, guide follicular and oocyte maturation, and promote correct chromosomal segregation in oocytes and early embryos.

The present invention provides devices having an elongated member, a stop slidably engaged with the member and preferably a measuring scale to determine dimensions of female reproductive organs. Preferably, the device is adapted to determine the length of the cervix in the fornix vaginae, which is used in the disclosed methods to predict the risk of preterm labor, risk of miscarriage, ease or difficulty of inducing labor, and fertility of an individual. Additional embodiments of the device determine dimensions of the fornix vaginae and dilation of the cervix uteri.

The invention provides a system and a method for real-time monitoring and communication of a housebound pregnant woman. A sensing device is used for sensing the uterine contractive pressure of the pregnant woman and physiological states, such as fetal heart rate, fetal movement, and the like of a fetus and generates a sensing signal; a computer-aided monitoring system carries out analytical processing and generates an analytical signal; a long-range electronic device downloads and displays the analytical signal from the computer-aided monitoring system, and the physiological states of the pregnant woman and the fetus can be judged to be abnormal or not through the analytical signal displayed by the electronic device, thus the physiological states of the pregnant woman can be monitored and known in a long range and real time, and the troubles of the pregnant woman staying in hospital for a long time for miscarriage prevention and other demands or going to the hospital back and forth frequently during pregnancy are reduced.

Methods for diagnosing risk of miscarriage and/or premature birth, foetal abnormalities, cancer (e.g. prostate cancer) and inflammatory disease (e.g. rheumatoid arthritis) are disclosed which involve determining abnormal levels of macrophage inhibitory cytokine-1 (MIC-1) in a body sample or, otherwise, determining the presence of a MIC-1 variant protein. Also disclosed are methods for reducing the risk of miscarriage and/or premature birth in pregnant subjects, and methods for treatment of inflammatory disease and/or cancer.

Disclosed is a method for using a first polar body and a second polar body as well as a single-cell embryo to carry out whole-genome non-exponential amplification and high-throughput genome sequencing, so as to perform preimplantation genetic diagnosis for genetic disease and testing for pathogenic genes causing repeated miscarriages. The method of the present invention comprises the following steps: (1) obtaining oocytes and embryos, and carrying out separation and genome amplification of first and second polar bodies and single-cell embryos; (2) establishing a genome sequencing library and sequencing, and carrying out bioinformatic analysis of the genome to obtain a gene spectrum and information concerning the number of copies of chromosomes and fragments thereof; (3) determining the chromosome ploidy of the polar bodies and embryos as well as information concerning defects, replication and point mutation in the chromosome fragments; (4) selecting normal or suitable embryos for implantation.

The present invention is directed to compositions of fetal hematopoietic stem and progenitor cells and stromal (mesencymal) cells derived from second trimester (16-20 weeks gestation) miscarriages, that are isolated, processed and cryopreserved, and the therapeutic uses of such stem and progenitor cells upon application. Such compositions may be useful for hematopoietic reconstitution and/or replacement in patients with various diseases and metabolic disorders. The invention also relates to methods for collecting, isolating, processing and cryopreserving of the fetal stem and progenitor cells of the invention. Importantly, the invention meets an urgent need in regenerative medicine while at the same time ensures utility of the product compositions because it utilizes fetal materials from second trimester (16-20 weeks of gestation) spontaneously lost pregnancies which are free of moral or ethical burdens.

The present invention concerns compositions and methods for preventing miscarriage and premature labor, and for treating and preventing Bacterial Vaginosis using a pH-buffering polymer. The present invention further concerns formulating such a composition or method in such a way as to provide therapeutically sufficient levels of the composition to a patient in need thereof.

The invention discloses a pregnant sow special-purposed bioactive feed additive, a feed premix, and a feed batch. The feed additive is prepared through the steps that: (1) a Chinese herbal medicine is prepared into Chinese herbal medicine powder, wherein the powder comprises the raw materials of, by weight: 15-30 parts of Mongolian milkvetch root, 6-15 parts of ligusticum, 10-25 parts of pilose asiabell root, 5-20 parts of largehead atractylodes rhizome, 5-20 parts of licorice root, 15-30 parts of immature tangerine fruit and dried tangerine peel, 10-40 parts of malt, 6-15 parts of Chinese pulsatilla, 8-20 parts of prepared rehmannia rhizome, and 16-40 parts of Szechwan lovage rhizome; (2) 15-20 parts by weight of a bioactive probiotics fermentation broth is uniformly mixed with 15 parts by weight of silicon dioxide; the mixture is subjected to low-temperature drying, such that a bioactive probiotics solid powder preparation is prepared; (3) 90% by weight of the Chinese herbal medicine powder obtained in the step (1) is uniformly mixed with 10% of the bioactive probiotics solid powder preparation obtained in the step (2), such that the feed additive is obtained. When the additive is used for feeding pregnant sows, healthy developments of fetuses in the mothers can be promoted. Also, pregnant sow miscarriage, stillbirths, mummified pig, postnatal hunger strike, mastitis, endometritis, and the like can be prevented. With the feed additive, piglet vitality and birth weight can be improved.

The invention discloses a health care biscuit with a grape taste. The health care biscuit is prepared by raw materials by parts as follows: 60-180 parts of flour, 20-25 parts of a soybean meal, 0.6-0.8 part of diastase, 2-3 parts of castanea seguinii dode leaves, 1-2 parts of morinda officinalis, 1-2 parts of desertliving cistanche, 1-2 parts of epimedium, 2-3 parts of Chinese mosla, 1-2 parts of lotus leaf bases, 2-3 parts of lotuses, 8-10 parts of grapes, 6-8 parts of coconut milk, 5-6 parts of Chinese hawthorn seed powder, 1-2 parts of baking soda, 1-2 parts of tartaric acid, 3-4 parts of white granulated sugar, 2-3 parts of honey, 3-4 parts of salt, 0.8-1.2 parts of active dry yeast, 0.6-0.9 parts of a sucrose fatty acid ester and an appropriate amount of water. The castanea seguinii dode leaves added to the biscuit prepared with the method is capable of enriching the blood, promotinglactation, clearing away heat and toxic material, reducing swelling and discharging pus; the morinda officinalis is capable of tonifying the kidney to strengthen yang, dispelling wind to eliminate dampness and strengthening tendons and bones; the Chinese mosla is capable of sweating, relieving summer heat, dredging water channels to eliminate dampness, warming the stomach and regulating middle energizer; the desertliving cistanche is capable of tonifying kidney yang, tonifying essence and blood and relaxing bowel; the lotus leaf bases are capable of relieving summer heat, eliminating dampness, stopping bleeding, preventing miscarriage and strengthening the middle warmer and benefiting vital energy; the lotuses are capable of promoting blood circulation to stop bleeding, dispelling wind and eliminating dampness, clearing away the heart-fire, cooling blood andclearing away heat and toxic material; and the biscuit is low in sugar content, crispy and tasty, can effectively replenish the energy required by a human body, and has good nutrition and health care values.

This invention teaches the use of chelating agents to diagnose and treat metal toxins in a patient. Chelation agents are given to the mother for the benefit of the baby. Metal toxins such as lead, arsenic, mercury, tin, antimony, aluminum and others are known to cause miscarriages, birth defects, maldevelopment of the organs and tissues and maldevelopment of the brain. Chelation treatments of the mother can prevent these problems in the embryo, fetus and infant. Removal of lead and mercury and other toxins allows improved development of the offspring, both during the chelation and alter the chelation is discontinued. Determining whether a mother who has just delivered a baby has elevated levels of heavy metals can also be used to identify the elevated metals of the mother as a possible cause of birth defects.

The invention discloses a probiotics Chinese herbal medicine composite biological preparation which comprises Chinese herbal medicine and composite probiotics. The weight ratio of the Chinese herbal medicine to the composite probiotics is 3:1 to 6:1; the Chinese herbal medicine comprises the following components in part by weight: 5 to 20 parts of rhizoma atractylodis, 5 to 20 parts of eucommia ulmoides oliv, 5 to 15 parts of fructus amomi, 10 to 15 parts of Szechuan lovage rhizome, 5 to 15 parts of rehmannia glutinosa, 5 to 20 parts of astragalus and 5 to 15 parts of himalayan teasel root; and the composite probiotics comprises the following components in part by weight: 5 to 20 parts of lactobacillus micro-capsule, 1 to 4 parts of bacillus subtilis and 1 to 4 parts of yeast. The probiotics Chinese herbal medicine composite biological preparation is prepared by mixing 7 types of Chinese herbal medicine and 3 types of probiotics according to a certain proportion, is mainly used for preventing miscarriages of a sow at the late stage of pregnancy, increasing weight of embryos in the uterus of the sow at the time and preventing various enteric diseases, and improves the nutritional level of the sow in the process of preventing miscarriages by utilizing the synergistic effect of the Chinese herbal medicine and the probiotics.

The invention discloses a turning gear of a steam turbine, comprising a driving motor, a reducer, a swinging gear, a large tooth ring and a clutch mechanism of the swinging gear which are connected in sequence; the large tooth ring is arranged on a rotor of the steam turbine and the reducer is provided with a multilevel speed-reducing transmission pair; the first-level speed-reducing transmission pair of the reducer is a planetary gear transmission box, a second-level speed-reducing transmission pair is an umbrella gear transmission pair and the rest is a planar gear speed-reducing transmission pair; a buffering spring is arranged between an inner tooth ring of the planetary gear transmission box and the box; the bearings of the swinging gear and the planar gear are rolling bearings; the swinging gear is positioned below the middle section of the rotor of the steam turbine and is corresponding to the large tooth ring in a tangential mode. The invention has the advantages of compact structure and small occupied area and has the buffering function with safety and reliability and without miscarriage when in use.

The invention provides a pregnant sow traditional Chinese medicine health feed and a preparation method thereof, and belongs to the technical field of feeds. The pregnant sow traditional Chinese medicine health feed is suitable for Xiangxi black pigs. The pregnant sow traditional Chinese medicine health feed includes, by weight: corn, soybean meal, wheat bran, folium eucommiae, a pregnant sow compound premix, compound probiotics, yeast cell walls and compound traditional Chinese medicine additives. The compound Chinese medicine additives include radix astragali, radix codonopsis, radix angelicae sinensis, radix achyranthis bidentatae, rhizoma atractylodis macrocephalae, liquorice root, poria cocos and fructus amomi. The preparation method is as below: smashing the corn, the soybean meal, the folium eucommiae, the wheat bran, and the compound traditional Chinese medicine additives to obtain mixed powder, mixing the mixed powder with the pregnant sow compound premix, the compound probiotics and the yeast cell walls, and conducting granulating. The pregnant sow traditional Chinese medicine health feed prepared through the preparation method has the effects of tranquilizing mind, preventing miscarriage, regulating spleen and stomach functions, activating intestinal flora, and reducing constipation. The pregnant sow traditional Chinese medicine health feed tends not to exhibit residuals, or cause drug resistance and toxic side effects, and is safe and reliable.

The invention discloses a feed for goats at a gestation period and a preparation method of the feed. The feed is prepared from the following raw materials in parts by weight: rice straw, chrysanthemum straw, urea, table salt, corn protein powder, linseed cakes, rapeseed meal, pitaya peel, barley, wild jujube leaves, Japanese pagodatree leaves and a compound additive. The feed disclosed by the invention is fine and uniform in granules, fresh and green in color, delicate and pleasant in fragrance and balanced in nutrition; the wild jujube leaves, the pitaya peel and the Japanese pagodatree leaves are added, so that pregnant goats can be promoted to calm, soothe the nerves, care babies and prevent miscarriage; composite treatment including ammoniation treatment and lactic acid fermentation is performed on straw raw materials, so that the digestibility of the feed is improved, and the palatability of the feed is improved; fine feed raw materials including the corn protein powder, the linseed cakes, the rapeseed meal, the barley and the like are compounded, so that the nutrition is supplemented, the requirements of breeding goats and the pregnant goats for raw materials for production are met, the healthy production of the breeding goats and the pregnant goats is guaranteed, besides, the immune functions of the goats are improved, and the weight and the survival rate of new-born lambs are increased.

The Chinese medicine consists of nine kinds of Chinese medicinal materials, including capillary artemisia, skullcap root, cape jasmine, parasitic loranthus, dodder seed, etc. It may be used in preventing and treating habitual abortion and dead fetus caused by ABO blood group incompatibility and RH blood group incompatibility between pregnant woman and fetus, and preventing and treating hyperbilirubinaemia encephalopathy of newborn baby caused by newborn baby hemolysis.

The invention discloses a continuous stamping bending die, which comprises an upper die base, a first end face, an upper pad, a fixed plate, a stopped baffle, a stripper plate, a material press block, a lower material floating block, a lower die base, a lower die angle, a lower support plate, a lower bending block, a material guide plate, a floating plate, a lower pad and a lower die plate; the continuous stamping bending die also comprises a plurality of punch heads, a guide pillar, a miscarriage detection pin and a slide block which are arranged on the upper die base. In this way, the continuous stamping bending die can finish punching, cutting off and two bending actions on a set of moulds, and simultaneously, the continuous stamping bending die is also equipped with a punching slide block; two kinds of standard products of the punching can be realized through installing or withdrawing the slide block, thereby enlarging the applicability of the mold, avoiding multiple sets of moulds, reducing the mould cost and the mould maintenance cost, greatly improving the processing efficiency of production, and realizing the continuous processing, so that the batch production is suitable; in addition, the continuous stamping bending die is equipped with the miscarriage detection pin so as to avoid processing wrongly and saving materials.

The invention provides a protocol leading to improved embryo implantation rates and/or decreased miscarriage rates in which hCG or LH, or a bio-analogue thereof, is administered during the follicular phase.