The invention provides a disinfectant for skin and mucous membrane tissue and a processing method thereof, which is characterized in that the formula of the disinfectant is composed of 2.5 grams of iodine, 50 grams of Sophora flavescens, 40 grams of Zanthoxylum bungeanum, 50 grams of Cortex Phellodendri, 20 grams of dried alum, alkane 30 grams of alcohol ether, 30 grams of phosphoric acid. The processing method of the disinfectant formula is: take Sophora flavescens, Zanthoxylum bungeanum, and dried alum, put them into a distillation tank respectively, add 7 times of water and heat to 110°C for 2 hours, filter out the medicinal solution and concentrate it to 1:1, add ethanol to precipitate for 24 hours , then the filtrate is ready for use; put the alkyl alcohol ether into the reaction tank, start the agitator, then take the iodine and put it into the rotating alkyl alcohol ether one after another, heat and stir at a constant temperature for emulsification for 90 hours, and form a brown fine paste emulsified iodine Standby; put the spare traditional Chinese medicine filtrate and paste-like emulsified iodine into the dilution tank, stir for 4 hours, take phosphoric acid and slowly put it into the dilution tank, adjust the pH value to detect the content of available iodine and traditional Chinese medicine, and divide when they reach the industry standard content Assemble to finished product. The present invention has the functions of high efficiency, quick-acting, long-acting, broad-spectrum, killing insects, relieving itching, hemostasis, relieving pain, astringent, dispelling, and repairing muscles. , Mucous membrane tissue without any damage and stimulation.