The invention relates to a traditional Chinese medicine composition for expelling toxin and repairing the immune system and bone diseases and a preparation method of the traditional Chinese medicine composition. India mustard seeds having the efficacy of warming the lung, eliminating phlegm, promoting circulation of Qi, eliminating stagnation, activating collaterals and relieving pain as well as Rhizoma Chuanxiong having the efficacy of promoting blood and qi circulation and dispelling wind and relieving pain are taken as monarch drugs, rhizoma kaempferiae having the efficacy of warming the middle Jiao to resolve dampness and promoting qi circulation to relieve pain is taken as a ministerial drug in compatibility, the drugs are reasonable in compatibility, all the components play a role in synergistic pesticide efficacy, and the organs and the immune system are repaired while toxin discharge is promoted, so that the traditional Chinese medicine composition can be used for treating various types of inflammation, rheumatism, rheumatoid arthritis, bone spur, sciatica, foot-hand paralysis, lumbar muscle strain, ligament injury, lumbar intervertebral disk pain, as well as diabetes, coronary heart disease, cerebral infarction, uremia, polycystic ovaries, asthma and the like, can relieve both primary and secondary symptoms and realize tonification and purgation in combination, and is proved to be good and lasting in curative effect and low in recurrence rate by clinical verifications. Besides, the preparation method of the traditional Chinese medicine composition is simple, pharmacological functions of the components are kept to the uttermost degree, safety is good, and high clinical and social value is realized.