The invention discloses a detachable self-cleaning industrial waste gas purification device. The device comprises a filter box, a first fan and a second fan, the first fan is mounted at an air inlet in the left side of the filter box, an air inlet pipe body is fixedly connected to an air inlet of the first fan, a mounting frame is connected to the inner side wall of the filter box in a clamping manner, and a first air conveying pipe is fixedly connected to an air outlet in the right side of the filtering box, the end, away from the filtering box, of the first air conveying pipe is fixedly connected with an opening in the right side wall of the adsorption box, a second air conveying pipe is fixedly connected to an opening in the left side wall of the adsorption box, and a second fan is installed at the end, away from the adsorption box, of the second air conveying pipe. According to the detachable self-cleaning industrial waste gas purification device, the filter screen is convenient toreplace and clean, disassembly is more convenient, impurities on the filter screen are convenient to automatically clean, the blockage phenomenon is avoided, in addition, the adsorption time of wastegas is prolonged, the adsorption efficiency of the waste gas is improved, and the practicability is improved.