The invention discloses a start-up method for an ex-situ prevulcanization secondary activity center hydrogenation catalyst. After resistance to air loss of a device is qualified, circulating
hydrogen compressor working load is adjusted to 0-20% of a maximum load, the catalyst reacts at a low temperature to release heat; when the
bed layer temperature rise to 60-150 DEG C, start-up activation oil is introduced, the circulating
hydrogen compressor working load is adjusted to 60-100% of the maximum load for
wetting of the catalyst; the start-up activation oil is cycled in a
reaction system closed path, the catalyst
bed temperature is risen to 180 to 230 DEG C by heat exchange; a proper amount of olefin-enriched
naphtha is added into the start-up activation oil, the catalyst
bed temperature is risen to 300-380 DEG C to complete start-up activation. The start-up method, in the premise of no influence on the use properties of the secondary activity center hydrogenation catalyst, can better use the catalyst characteristics, reduce the device
energy consumption, and reduce the device
investment cost, and the start-up process can be simplified.