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64results about How to "Clear treatment effect" patented technology
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Sustained-release preparation for AII antagonist, production and use thereof
InactiveUS6589547B1Reduce the amount of solutionControlled release ratePowder deliveryOrganic active ingredientsBlood pressureCircadian rhythm
The present invention is to provide a sustained-release preparation which comprises a compound having angiotensin II antagonistic activity, its pro-drug or their salt, and a biodegradable polymer, and if necessary, a polyvalent metal, and which is highly stable and active and shows angiotensin II antagonistic activity while maintaining circadian rhythm of blood pressure for a long time.
Owner:TAKEDA PHARMA CO LTD
Application of butylbenzene phthalein homolog in preparation of medicine for treating cerebral ischemia disease
The present invention relates to the application of butyl benzene phthalein homolog in preparing medicine for preventing and treating cerebral ischemic disease, resisting platelet aggregation and thrombus and preventing and treating dementia. The butyl benzene phthalein homolog is 3-(3'-hydroxy) butyl benzene phthalein or 3-hydroxy-3-butyl benzene phthalein.
Owner:CSPC ZHONGQI PHARM TECH (SHIJIAZHUANG) CO LTD +1
Pharmaceutical composition for treating bedsore and preparation method thereof
InactiveCN102091309AClear treatment effectGood curative effectAnthropod material medical ingredientsDermatological disorderHalloysiteTherapeutic effect
The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating bedsore and a preparation method thereof. The pharmaceutical composition provided by the invention comprises the following crude medicines in parts by weight: 30-70 parts of rhizoma bletillae, 20-40 parts of kuh-seng, 20-40 parts of Chinese waxgourd peel, 20-40 parts of job's-tears seed, 5-30 parts of armand clematis stem, 5-30 parts of dried ginger, 10-50 parts of honeycomb, 5-30 parts of pepper, 5-30 parts of chilli, 10-50 parts of catechu, 10-40 parts of atractylodes rhizome, 20-80 parts of red halloysite, 10-60 parts of gallnut, 10-40 parts of chuanxiong rhizome and 5-40 parts of Japanese ampelopsis root. The pharmaceutical composition achieves the purpose of treating bedsore by sterilizing, promoting diuresis, detoxicating and promoting tissue regeneration, and the pharmaceutical composition has definite, stable and controllable curative effects on treating bedsore.
Owner:陈晓玲
Traditional Chinese medicine composition for treating poultry hydropericardium
ActiveCN105535198AFunction increaseReduce viscosityDispersion deliveryBlood disorderTherapeutic effectAnimal product
The invention discloses a traditional Chinese medicine composition for treating poultry hydropericardium. The traditional Chinese medicine composition is prepared from the following raw materials in percentage by weight: 10 percent to 40 percent of radix aconiti lateralis preparata, 10 percent to 30 percent of cortex cinnamomi, 5 percent to 20 percent of Chinese angelica, 5 percent to 20 percent of rhizoma Chuanxiong, 5 percent to 20 percent of tangerine peels, 5 percent to 15 percent of radix paeoniae alba, 5 percent to 15 percent of rhizoma atractylodis macrocephalae, 5 percent to 15 percent of poria cocos, 2 percent to 10 percent of ginseng leaves, 2 percent to 15 percent of prepared liquorice roots and 2 percent to 15 percent of fructus jujubae. The traditional Chinese medicine composition prepared by the invention accords with traditional Chinese medicine and veterinary medicine basic theories and can be used in a veterinary clinic. According to the traditional Chinese medicine composition as well as an application method and dosage of the traditional Chinese medicine composition, the traditional Chinese medicine composition has a definite treatment effect on the poultry hydropericardium, has a protection function on liver and has very good protection and rehabilitation functions on immune organs including kidneys, ovaries, thymus glands, bursa of fabricius and the like; after the medicine is digested and absorbed, the flavor of animal products (meat protein) can be improved; a defect of chemical drug residues is also avoided and a market requirements prospect is wide.
Owner:青岛信诺邦生物科技有限公司 +1
Pharmaceutical composition for treating thrombocytopenia, and preparation method and application thereof
InactiveCN102441063AClear treatment effectGood curative effectBlood disorderExtracellular fluid disorderMedicineGinseng
The invention specifically relates to a pharmaceutical composition for treating thrombocytopenia, and a preparation method and application thereof, belonging to the field of Chinese medicines. The invention provides a novel pharmaceutical composition for treating thrombocytopenia, and the pharmaceutical composition is prepared from the raw materials of hairyvein agrimony, cortex moutan radicis, gentrin knotweed, glutinous rehmannia, radix astragali, cape jasmine and pseudo-ginseng, has the functions of nourishing yin, tonifying blood, clearing heat and cooling the blood, and can be used for patients who suffer from bleeding, thrombocytopenia and the like caused by deficiency of yin and hot blood. Application of the pharmaceutical composition enables the purpose of the treating thrombocytopenia to be realized.
Owner:CHENGDU KANGHEXIN MEDICAL TECH
Pharmaceutical composite for curing colon cancer and preparing method thereof
InactiveCN101700394AClear treatment effectGood anticancer effectAntineoplastic agentsPlant ingredientsInternal resistanceToxic material
The invention belongs to the medicine field, particularly relates to a pharmaceutical composite for curing colon cancer and a preparing method thereof. The technical problem solved by the invention is to provide a brand-new pharmaceutical composite for curing colon cancer and a preparation method thereof. The pharmaceutical composition comprises the following components: 5-11 parts of rucea javanica, 5-11 parts of common camptotheca fruit, 8-16 parts of semen coicis and / or sargentgloryvinestem, 8-16 parts of curcumaaromaticaSalisb, and 5-16 parts of gingseng and / or campanumaea pilosula. The pharmaceutical composition has efficacies of clearing away heat and toxic material, activating blood circulation, removing masses, benefiting vital energy and strengthening healthy energy and the like.Long-term clinic observation and series of experimental researches show that the pharmaceutical composition has good anti-cancer effect, especially has obvious curative effect. The parasitical composition mainly cures patients of colon cancer suffering from toxin and phlegm internal resistance and qi deficiency, has the symptoms of abdominal pain, fixed pain spot, unpalpable pain, abdominalmass, abdominal distention, acratia, anorexia, dark-purple tongue or tongue with blockage points or ecchymosises, white and greasy tongue coat, and pulse fine tart, and is used by patients of colon cancer or colon cancer postoperation dialectical species suffering from toxin and phlegm internal resistance and qi deficiency.
Owner:CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
Preparation method of flavonoid medicine for treating frostbite
InactiveCN103181961ADefinite curative effectSimple recipeAntipyreticAerosol deliveryRotary evaporatorMedicine
The invention relates to a preparation method of a flavonoid medicine for treating frostbite, which comprises the following steps: weighting fresh nanking cherry, washing and crushing, removing the shell to obtain a basic solution, adding 75% of ethanol containing 1% of hydrochloric acid with volume ratio of 1:4, wherein the ultrasonic frequency is 40KHz, extracting for 10-60 minutes, performing backflow extraction for 1-6 hours, performing pressure reduction and concentrating to alcohol amount at 75%, then standing away from light for 6-18 hours and filtering the deposition, and placing a filtrate in a rotary evaporation instrument for performing pressure reduction and concentrating to a dry state, suspending a concentrate and dispersing in water, filtering to remove an insoluble substance, filling the filtrate in a polyamide column, adding water with 30 times amount of polyamide for eluting, removing an eluate, adding 90% of ethanol for eluting to make the eluate transparent, collecting the eluate and performing pressure reduction and concentrating, and performing vacuum freeze drying on a concentrate to obtain the flavonoid medicine. The flavonoid medicine for treating frostbite has the characteristics of single component, definite therapeutic effect and convenient usage.
Owner:BEIHUA UNIV
Attaching-type heart function monitoring and/or intervening system
PendingCN107049232AAccurate monitoringDynamic MonitoringPhysical therapyMedical devicesFunctional indicesElectricity
Owner:周晓辉
Chinese medicine composition for curing bone fracture, bone-breaking muscle-injuring, blood stasis
InactiveCN101181386AReasonable compositionClear treatment effectAerosol deliveryOintment deliveryHerbTreatment effect
The invention relates to a Chinese traditional medical compound for curing fracture, boon stump and injury of tendon and muscle and haemostasis. The invention is made of the raw materials by weight proportion and carriers which are acceptable on pharmacy of radix astragali, radix codonopsis pilosulae, tail of angelica, cortex periplocae, szechuan lovage rhizome, safflower, red paeony root, eucommia ulmoides, rhizome drynaria, diverse wormwood herb, cassia twig, medicinal cyathula root and pawpaw. The invention having the advantages of rational components and obvious curing effect can greatly decrease the pain of patients due to the fracture.
Owner:郭云胜
Clindamycin phosphate vaginal sustained-release gel and its preparation method
InactiveCN102335113AClear treatment effectExtended stayAntibacterial agentsOrganic active ingredientsCarboxymethyl celluloseGynecology
The invention relates to a clindamycin phosphate vaginal sustained-release gel and its preparation method. The clindamycin phosphate vaginal sustained-release gel comprises the following components of: by weight, 1-5% of clindamycin phosphate, 5-15% of poloxamer (188), 8-20% of poloxamer (407), 0.5-2% of sodium carboxymethyl cellulose, 0.05-2% of carbomer (980), 0.02-5% of an additive and the balance being water. The clindamycin phosphate vaginal sustained-release gel provided by the invention has advantages of clear curative effect, long detention time in vagina, sustained release of the drug effect, long onset time and good compliance of patients.
Owner:HANGZHOU SHARPLY PHARM R&D INSTIT +2
Whole-course supervision system and method for soft tissue tumor informatization pathology auxiliary diagnosis
ActiveCN112802600AGood serviceIntegrity guaranteedMedical data miningMedical automated diagnosisData platformClinical data management
The invention belongs to the field of tumor information processing, and provides a whole-course supervision system and method for soft tissue tumor informatization pathology auxiliary diagnosis. The system comprises: a clinical data management platform in which clinical data of soft tissue tumors and expression profiles or / and characteristic spectra of different types of soft tissue tumors at different levels are pre-stored; a pathological diagnosis data platform which is used for receiving clinical data, pathological histological images, immunohistochemical results and molecular genetics results of patients to form expression profiles or / and characteristic spectra of different levels, comparing the expression profiles or / and characteristic spectra with the expression profiles or / and characteristic spectra of corresponding levels in the clinical data management platform, determining the same tumor type determined at different levels as a final pathological diagnosis type, and generating a standardized diagnosis report; and a prognosis data information platform which is used for evaluating prognosis risk factors and feeding back the prognosis risk factors to the pathological diagnosis data platform, establishing a clinical prediction model, evaluating the survival rate, regularly prompting follow-up visit patient time and content, and recording follow-up visit information.
Owner:SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG FIRST MEDICAL UNIVERSITY
Medicinal composition for treating cough and preparation method and application thereof
ActiveCN101053600ATo achieve the purpose of treatmentGood drug compatibilityAntiinfectivesRespiratory disorderDiseaseTherapeutic intent
The invention relates to a medicine combination for treating cold belonging to medical field. The material of the active components are as followed by weight: kudzu root 4-8, ephedra herb 2-4, cassia twig 2-4, paeonia lactiflora pallas 2-4, bitter almond kernel 2-4. The invention has a plurality of functions such as remarkable bacteriostasis, antivirus, relieving fever, analgesic effect, antiinflammatory, relieving cough, eliminating phlegm and promoting red cell immunity so as to provide a new choose for clinical treatment for cold, especially exogenous pathogenic fever disease.
Owner:SICHUAN YIBIN WULIANGYE GROUP
Pharmaceutical composition for curing tristimania and preparation method and application thereof
InactiveCN101919924AGood treatment effectClear treatment effectNervous disorderInanimate material medical ingredientsCassiaSide effect
The invention discloses a pharmaceutical composition for curing tristimania and a preparation method and an application thereof. The pharmaceutical composition comprises the following components in parts by mass: 3-60 parts of cassia twig, 3-60 parts of liquorice and 6-90 parts of Morinda officinalis. Based on different properties of drugs, the invention respectively adopts the modes of extracting by volatile oil, decocting by water, extracting by ethanol and the like to extract effective components so as to obtain the pharmaceutical composition in the invention. The pharmaceutical composition has the efficacies of regulating heart-yang, keep ying and weiqi balance, tonifying qi and calming heart, can be used for preparing drugs for curing tristimania and has obvious and safe curative effect on tristimania with small toxic or side effect.
Owner:GUANGDONG PHARMA UNIV
Medicinal composition for treating Hashimoto's thyroiditis, and preparation method and use thereof
ActiveCN107158084AClear treatment effectCraft economyImmunological disordersEndocrine system disorderIn vivoActive ingredient
The invention belongs to the fields of traditional Chinese medicines and natural medicine pharmaceuticals, and concretely relates to a medicinal composition for treating Hashimoto's thyroiditis, and a preparation method and a use thereof. The medicinal composition for treating Hashimoto's thyroiditis comprises, by weight, 1 part of snakegourd peel and 1-20 parts of dried figs. The snakegourd peel and the dried figs are preferably selected according to the above weight proportions, and are processed through steps to prepare polysaccharide extract, and pharmaceutically-acceptable or health product-acceptable auxiliary materials are added to prepare a conventional oral preparation. A result of experiments of in vivo and in vivo anti-thyroid cancer pharmacological effects of the extract shows that the polysaccharide extract can reduce the high-titer autoantibodiesTGAb and TPOAb of HT, reduce IL-2, increase IL-4, inhibit the hyperthyroidism of Th1 cell functions and promote the drift of Th1 to Th2 in order to alleviate the Hashimoto's thyroiditis.
Owner:SICHUAN UNIV
Application of thyme compound plant essential oil in preventing necrotic enteritis
ActiveCN107260796AImprove accuracyBig amount of dataAntibacterial agentsDigestive systemCoccidiosisBacillus perfringens
The invention discloses an application of thyme compound plant essential oil in preventing necrotic enteritis. The plant essential oil contains thyme-nutmeg compound essential oil and thyme-basil compound essential oil. An applicator is successful in constructing an animal model with necrotic enteritis through 1-2 years. For the model, wheat basal feed is used for feeding, and fish meal is added at the later period; clostridium perfringens is adopted for independently attacking toxicity, and the classic lesions is obvious; and the phenomenon of mixing of a previous coccidium concurrent model and coccidiosis can be eliminated. The application disclosed by the invention has the advantages that the test period is short and the repeatability is high. In addition to an in-vitro experiment, the applicator also utilizes the model to study the in-vivo control effect of the plant essential oil to really define the preventing and treating effects of the plant essential oil for the necrotic enteritis.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
Pharmaceutical composition for treating bedsore and preparation method thereof
InactiveCN102091309BClear treatment effectGood curative effectAnthropod material medical ingredientsDermatological disorderClematisHalloysite
The invention belongs to the field of medicine, and in particular relates to a pharmaceutical composition for treating bedsore and a preparation method thereof. The pharmaceutical composition provided by the invention comprises the following crude medicines in parts by weight: 30-70 parts of rhizoma bletillae, 20-40 parts of kuh-seng, 20-40 parts of Chinese waxgourd peel, 20-40 parts of job's-tears seed, 5-30 parts of armand clematis stem, 5-30 parts of dried ginger, 10-50 parts of honeycomb, 5-30 parts of pepper, 5-30 parts of chilli, 10-50 parts of catechu, 10-40 parts of atractylodes rhizome, 20-80 parts of red halloysite, 10-60 parts of gallnut, 10-40 parts of chuanxiong rhizome and 5-40 parts of Japanese ampelopsis root. The pharmaceutical composition achieves the purpose of treatingbedsore by sterilizing, promoting diuresis, detoxicating and promoting tissue regeneration, and the pharmaceutical composition has definite, stable and controllable curative effects on treating bedsore.
Owner:陈晓玲
Application of PC2 gene or recombinant virus expressing PC2 gene to preparation of medicament for treating osteoarthritis
ActiveCN109395094AClear treatment effectExpand the range of optionsAntipyreticAnalgesicsTherapeutic effectGene therapy for osteoarthritis
The invention discloses application of a PC2 gene or a recombinant virus expressing the PC2 gene to preparation of a medicament for treating osteoarthritis. The invention provides application of the PC2 gene to the preparation of a medicament for treating osteoarthritis. The PC2 gene is a gene coded with a PC2 protein.The PC2 protein is a protein consists of an amino acid sequence shown as a sequence 1 in a sequence table. As proved by the inventor of the invention, the PC2 gene has a definite treatment effect on osteoarthritis, so that a new thought is provided for the development of a gene applied to osteoarthritis treatment, and the selection range of clinical gene treatment is enlarged. The PC2 gene has important application and popularization value.
Owner:INST OF ZOOLOGY CHINESE ACAD OF SCI
Application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis
ActiveCN107375413AImprove accuracyBig amount of dataAntibacterial agentsDigestive systemCoccidiosisBacillus perfringens
The invention discloses an application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis. Plant essential oil includes mutmeng pure essential oil, basil pure essential oil or mutmeng-basil compound essential oil. The applicant spends one to two years and successfully builds an animal model of the necrotic enteritis. The model is feed with wheat basal diet, and fish meal is added in a later period; clostridium perfringens is adopted to counteract toxic substances independently, and typical pathological changes are obvious; and the previous phenomenon that a coccidium concurrent model and coccidiosis are confused can be excluded. The experiment period is short, and the repeatability is high. In addition to in-vitro experiments, the applicant also takes use of the model to do research on the in-vivo control effect of the plant essential oil, and it is really clear that the plant essential oil has the effects of preventing and curing the necrotic enteritis.
Owner:INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
Medicine composition for treating prostatitis and preparation method and application thereof
ActiveCN102670807AHas antibacterial and antibacterial abilityClear treatment effectUrinary disorderPlant ingredientsTraditional medicineActive ingredient
The invention discloses a medicine composition for treating prostatitis. The medicine composition is prepared from the following raw material medicines in parts by weight: 28-32 parts of herba leonuri, 13-17 parts of rhizoma polygoni cuspidati, 10-14 parts of cortex phellodendri and 1-7 parts of cinnamon. The medicine disclosed by the invention can obviously improve the indexes of prostatitis, is used for treating chronic prostatitis, and has relatively great values in practical application.
Owner:CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
Traditional Chinese medicine compound preparation for preventing and treating climacteric syndrome and preparation method of traditional Chinese medicine compound preparation
InactiveCN110575495AReduced voluntary activityReduce imbalancePharmaceutical delivery mechanismSexual disorderLiver and kidneyTherapeutic effect
The invention provides a traditional Chinese medicine compound preparation for preventing and treating climacteric syndrome, and belongs to the field of traditional Chinese medicine. According to thetraditional Chinese medicine compound preparation, ligustrum lucidum ait, fructus lycii, radix ophiopogonis, white peony root, mulberry leaf, chrysanthemum and cortex lycii radicis are used as bulk pharmaceutical chemicals for composition, so that the efficacy of each medicine is synergistic, and the effects of nourishing liver and kidney and clearing heat and benefiting Yin are achieved. The results of pharmacodynamic experiments show that the traditional Chinese medicine compound preparation has a certain prevention and treatment effect on the climacteric syndrome. The medicine is made of pure natural Chinese medicinal materials as raw materials and is prepared into an oral preparation by using the conventional pharmacological process and auxiliary materials, and the traditional Chinesemedicine compound preparation for preventing and treating the climacteric syndrome is safe and non-toxic, and is further an ideal health care product.
Owner:GANSU UNIV OF CHINESE MEDICINE
Chinese medicinal compound for treating insomnia in female climacteric
InactiveCN103006826AScore lowerHelp absorptionNervous disorderSexual disorderTherapeutic effectRhizome
The invention discloses a Chinese medicinal compound for treating insomnia in female climacteric, which consists of the following components by weight: 30g of glossy privet fruit, 15g of eclipta alba, 30g of raw astragalus, 15g of radix pseudostellariae, 15g of roasted bighead atractylodes rhizome, 20g of Chinese angelica, 30g of raw oyster, 30g of spina date seed, 20g of white peony root, 12g of thinleaf milkwort root bark, 20g of red-rooted salvia root, and 6g of costustoot. According to the Chinese medicinal compound, the sleeping situation of a patient suffering insomnia in climacteric can be remarkably improved. The Chinese medicinal compound is used for treating both heart and kidney, regulating qi and blood and restoring normal coordination between heart and kidney, and has an exact treatment effect to insomnia in climacteric.
Owner:NINGXIA MEDICAL UNIV
Ultrasonic probe having gradient information and device for ultrasonic diagnosis and treatment using same
InactiveCN104582587AClear treatment effectUltrasound therapyMaterial analysis using sonic/ultrasonic/infrasonic wavesTreatment useBiomedical engineering
Disclosed are a probe having gradient information and a device for ultrasonic diagnosis and treatment using the same. The ultrasonic probe having gradient information according to the present invention comprises a probe unit for generating an ultrasonic signal for diagnosis or treatment and radiating the generated ultrasonic signal to an object; and a gradient information collecting unit for collecting the gradient information on the ultrasonic probe equipped with the probe unit.
Owner:NOHSN +1
Gynecological health caring and face nourishing compound
InactiveCN107243057AGood softening and eliminating effectDry skin syndrome relief and treatmentAntinoxious agentsDermatological disorderBreast cystsBreast Hyperplasia
The invention provides a gynecological health caring and face nourishing compound. The compound is any dosage form mainly made from coix seeds, dahurian angelica root, lily, parched hawthorn fruit, raspberry and Radix Puerariae through a conventional method of traditional Chinese medicine pharmacy. Clinical and experimental data prove that the compound has very good conditioning and health caring effects on female irregular menstruation, uterine fibroids and uterine, has specific maintaining and health caring effects on problems of women's ovaries and ovarian appendage, has an excellent conditioning effect on women's leucorrhea, has very good softening and eliminating effects on women's breast hyperplasia and breast cysts, has specific breast enlarging, breast strengthening, breast lifting and breast beautifying effects, and has specific alleviation and treatment effects on female skin appearance premature aging, chloasma, acnes, chronic facial recurrent dermatitis and skin dry syndromes.
Owner:中健娇美肤传统医学研究科技有限责任公司
Traditional Chinese medicine composition for treating vascular dementia and preparation thereof
ActiveCN114558058AClear treatment effectClear curative effectNervous disorderPteridophyta/filicophyta medical ingredientsMedicinal herbsLycopodium clavatum
The invention relates to a traditional Chinese medicine preparation, and discloses a traditional Chinese medicine composition for treating vascular dementia, which comprises the following raw medicinal materials: polygala tenuifolia, storax, hippocampus, lycopodium clavatum, turtle shell, scalded rhizoma cibotii, caulis spatholobi, vine of multiflower knotweed, rhizoma atractylodis, cimicifugae foetidae and pomegranate seed. Wherein the content of the radix polygalae is 5 to 15 parts by weight, the content of the storax is 0.3 to 1 part by weight, the content of the sea horse is 3 to 9 parts by weight, the content of the lycopodium clavatum is 3 to 15 parts by weight, the content of the turtle shell is 9 to 30 parts by weight, the content of the hot rhizoma cibotii is 6 to 15 parts by weight, the content of the caulis spatholobi is 9 to 15 parts by weight, the content of the caulis polygoni multiflori is 9 to 15 parts by weight, and the content of the rhizoma atractylodis is 3 to 12 parts by weight. The content of the rhizoma cimicifugae is 3-15 parts by weight, and the content of the pomegranate seeds is 5-15 parts by weight. The traditional Chinese medicine composition for treating vascular dementia has the effects of tonifying the kidney, nourishing blood, reducing phlegm, dredging collaterals, soothing the nerves and promoting intelligence, and can be used for treating vascular dementia, improving the cognitive ability of patients and improving dementia symptoms. The invention also provides a medicinal preparation for treating vascular dementia.
Owner:HUNAN UNIV OF CHINESE MEDICINE
Medicinal composition for treating cough and preparation method and application thereof
ActiveCN101053600BTo achieve the purpose of treatmentGood drug compatibilityAntiinfectivesRespiratory disorderDiseaseTherapeutic intent
Owner:SICHUAN YIBIN WULIANGYE GROUP
An eight immortal flower leaf extract and its drug composition, preparation method and application
ActiveCN107213176BHigh in total phenolic acidsStable and controllable qualityAntineoplastic agentsPlant ingredientsAqueous ethanolTherapeutic effect
Owner:SICHUAN UNIV
Preparation method of a specific demineralized extracellular matrix scaffold of cross-linked antibiotics
ActiveCN112618797BGood biocompatibilityImprove biological activityTissue regenerationProsthesisTherapeutic effectDrug release
The invention discloses a preparation method of a cross-linked antibiotic specific demineralized extracellular matrix scaffold, and belongs to the technical field of bone infection treatment. The invention discloses a method for preparing a specific demineralized extracellular matrix scaffold of cross-linked antibiotics. The specific demineralized and decellularized cancellous bone extracellular matrix scaffold (SDECM) is used as a substrate, and the specific demineralized and decellularized cancellous bone extracellular matrix scaffold (SDECM) is used as a substrate, and the antibiotic is electrostatically adsorbed and chemically adsorbed. Cross-linking two forms of composite drug loading, releasing antibiotics through rapid pH response and accompanying material degradation in an acidic environment, anti-infection through antibiotics and promoting repair through SDECM, so as to achieve pH-sensitive drug release in an acidic environment in the early stage of infection Rapid sterilization, sustained sterilization by slow release of drugs in the mid-late physiological environment, and permanent sterilization ability to prevent infection recurrence in the absence of infection provide new ideas and tools for the antibacterial and repairing treatment of bone infections.
Owner:杭州源囊生物科技有限公司
A kind of veterinary drug composition and its preparation method and application
ActiveCN108175793BReduce dosageSmall toxicityAntiparasitic agentsHeterocyclic compound active ingredientsBiotechnologySide effect
The invention provides a veterinary drug composition. The veterinary drug composition comprises, by mass, 5-25 parts of toltrazuril, 2.5-15 parts of decoquinate, 1-12 parts of pyrantel, 8-15 parts ofCortex Meliae, 2-8 parts of Chenopodium ambrosioides, 2-6 parts of Herb of Longseed Willowweed, 5-10 parts of Rhizoma Atractylodis Macrocephalae, 3-8 parts of dried orange peel and 5-10 parts of darkplum. The invention also provides a preparation method and an application of the veterinary drug composition. The veterinary drug composition has the advantages of reasonable compatibility, quick effect, minimal toxic and side effects, effective reduction of the drug resistance and drug residues, very clear therapeutic effect on intestinal injuries, reduced appetite and lean bodies of animals, caused by coccidiosis, low cost, and easiness in use. The invention further provides the application of the composition in the treatment of histomoniasis.
Owner:JIANGSU LINGYUN PHARMA
Application of coyne in the preparation of antiallergic drugs
ActiveCN111166739BReduced degranulationImprove allergic symptomsOrganic active ingredientsImmunological disordersDiseaseStaining
The invention discloses the application of coyne in the preparation of anti-allergic drugs, by comparing the degranulation of KU812 cells, the degree of swelling of the toes, the degree of Evans blue exudation of the toes, HE staining of foot skin tissue sections, and the release of serum histamine To evaluate the drug group to be tested, the normal saline control group and the normal control group, to evaluate the therapeutic effect of the drug on allergic diseases, and to determine that coyne can be used in the preparation of anti-allergic drugs. Coin can effectively alleviate the symptoms of local and systemic allergic reactions in mice; reduce mast cell degranulation and significantly improve the symptoms caused by allergic reactions.
Owner:XI AN JIAOTONG UNIV
A pharmaceutical composition for preventing and treating myocardial ischemia, its preparation method and application
ActiveCN106620707BClear treatment effectImprove securityCapsule deliveryHeterocyclic compound active ingredientsAspirinActive component
The invention relates to a pharmaceutical composition for preventing and treating myocardial ischemia as well as a preparation and an application thereof. The pharmaceutical composition employs sphingosine-1-phosphate, naproxen and an anticoagulant medicine as medicinal active components, wherein the anticoagulant medicine is selected from heparin, dicoumarol, acetonyl benzyl hydroxycoumarin, aspirin and the like, and preferably dicoumarol. Synergistically interacted multi-path between medicinal active components of the pharmaceutical composition perform effects for prevention and treatment of myocardial ischemia, and improve myocardial ischemic electrocardiogram change and anticoagulation. The pharmaceutical composition can be taken orally or applied parenterally, in order to effectively prevent and treat myocardial ischemia, prevent and alleviate angina pectoris, myocardial infarction or ischemic cardiomyopathy, and the like.
Owner:MUDANJIANG MEDICAL UNIV
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