A kind of veterinary drug composition and its preparation method and application
A composition and veterinary drug technology, applied in the direction of drug combination, pharmaceutical formula, heterocyclic compound active ingredients, etc., can solve the inconvenience of drug use, slow curative effect, poisoning, such as polyether ionophore antibiotics maduramycin, monen Mycocin, salinomycin, etc.
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Embodiment 1
[0034] The raw materials were weighed according to the parts by mass of 5 toltrazuril, 15 decoxyquinate, 1 pyrantel, 15 bark of neem, 8 nepeta, 2 gallbladder, 5 atractylodes rhizome, 3 tangerine peel and 10 black plum.
[0035] Neem bark, nepeta chinensis, heart Gallbladder, Atractylodes macrocephala, tangerine peel, and black plum were powdered to 60 mesh, mixed well, and sterilized by cobalt-60 irradiation to prepare a mixture of traditional Chinese medicines.
[0036] Toltrazuril, decoquinate, pyrantel and traditional Chinese medicine mixture are mixed, food coloring is added, mixed and dried to prepare powder.
Embodiment 2
[0038] The raw materials were weighed according to the mass parts of 25 toltrazuril, 2.5 decoxyquinate, 12 pyrantel, 8 neem bark, 2 nepetae, 6 gallbladder grass, 10 atractylodes rhizome, 8 tangerine peel, and 5 ebony.
[0039] Neem bark, nepeta chinensis, heart Gallbladder, Atractylodes macrocephala, tangerine peel, and black plum were powdered to 100 mesh, mixed evenly, and sterilized with 75% ethanol to obtain a mixture of traditional Chinese medicines.
[0040] Toltrazuril, decoquinate, pyrantel and traditional Chinese medicine mixture are mixed evenly, magnesium stearate and food coloring are added, mixed evenly, dried, and compressed into tablets to prepare tablets.
Embodiment 3
[0042] The raw materials were weighed according to the parts by mass of toltrazuril 10, decoquinate 10, pyrantel 6, neem bark 12, nepeta chinensis 7, heart gallbladder 3, atractylodes rhizome 9, tangerine peel 6, and black plum 6.
[0043]Nepeta chinensis and tangerine peel are extracted by steam distillation; neem bark, heart gallbladder, Atractylodes macrocephala, and black plum are crushed, passed through a 50-mesh sieve, extracted with water 6 times the weight of the powder for 5 hours, left to stand, cooled, and the extract after filtering the residue is concentrated Make a clear paste with a relative density of 1.10-1.25 at 60°C.
[0044] Mix tortrazuril, decoquinate and pyrantel with the extracted volatile oil and clear ointment, stir thoroughly and then spray dry, add magnesium stearate to the obtained spray-dried powder, compress into tablets to prepare tablets.
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