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Traditional Chinese medicine composition for treating vascular dementia and preparation thereof

A technology for vascular dementia and pharmaceutical preparations, applied in the field of traditional Chinese medicine compositions for the treatment of vascular dementia, and traditional Chinese medicine preparations for the treatment of vascular dementia

Active Publication Date: 2022-05-31
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current traditional Chinese medicine treatment of VD mainly focuses on resolving stagnation and dissipating stagnation, tonifying deficiency and benefiting damage. However, due to the diversity of VD pathogenesis and the complexity of human cognition and memory mechanisms, there is no recognized safe and effective treatment for VD in this field. traditional Chinese medicine

Method used

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  • Traditional Chinese medicine composition for treating vascular dementia and preparation thereof
  • Traditional Chinese medicine composition for treating vascular dementia and preparation thereof
  • Traditional Chinese medicine composition for treating vascular dementia and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] This example is used to prepare the powder of the traditional Chinese medicine composition for treating vascular dementia of the present invention.

[0041] (1) Preparation of extract A: Take 100g Tanggouji, 120g Caulis Spatholobus, 120g Shouwuteng and 100g pomegranate seeds, add 2600g water, bring to a boil with strong fire, change to slow fire and continue heating for 90 minutes, filter with traditional Chinese medicine sieve, and obtain The first filtrate; add 1800g water to the medicine dregs again, bring to a boil with strong fire, change to a slow fire and continue heating for 60 minutes, use a traditional Chinese medicine sieve to filter out the medicine residue, and obtain the second filtrate. The first filtrate and the second filtrate were combined together, placed in a vacuum dryer, and dried at a temperature of 50° C. and a pressure of 6 KPa until the weight no longer decreased to obtain Extract A powder.

[0042] (2) Preparation of extract B: take 100g polyg...

Embodiment 2

[0046] This example is used to prepare the powder of the traditional Chinese medicine composition for treating vascular dementia of the present invention.

[0047] (1) Preparation of extract A: Take 80g Tanggouji, 130g Caulis Spatholobus, 110g Radix Polygoni Multiflori and 120g pomegranate seeds, add 3500g water, bring to a boil with strong fire, change to slow fire and continue heating for 130 minutes, filter with traditional Chinese medicine sieve, and obtain Filtrate; place the filtrate in a vacuum dryer, dry at a temperature of 60° C. and a pressure of 6 KPa until the weight no longer decreases, and extract A powder is obtained.

[0048] (2) Preparation of extract B: take 80g polygala, 60g hippocampus, 80g Shenjincao, 110g herb atractylodes and 80g Cimicifuga, pulverize them with a traditional Chinese medicine grinder, take 220g turtle shells, fry them with sand and quench them with vinegar, and mash them; The above-mentioned medicinal materials are minced and mixed, and 3...

Embodiment 3

[0052] This example is used to prepare the powder of the traditional Chinese medicine composition for treating vascular dementia of the present invention.

[0053] (1) Preparation of extract A: Take 120g Tanggouji, 110g Caulis Spatholobus, 130g Shouwuteng and 80g pomegranate seeds, add 3300g water, bring to a boil with strong fire, change to slow fire and continue heating for 110 minutes, filter with a traditional Chinese medicine sieve, and obtain The first filtrate; add 2000g of water to the medicinal residues, bring to a boil with high heat, change to a slow fire and continue heating for 70 minutes, use a traditional Chinese medicine sieve to filter the medicinal residues, and obtain the second filtrate. The first filtrate and the second filtrate were combined, placed in a vacuum dryer, and dried at a temperature of 50° C. and a pressure of 5 KPa until the weight no longer decreased to obtain Extract A powder.

[0054] (2) Preparation of extract B: take 120g polygala, 40g h...

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Abstract

The invention relates to a traditional Chinese medicine preparation, and discloses a traditional Chinese medicine composition for treating vascular dementia, which comprises the following raw medicinal materials: polygala tenuifolia, storax, hippocampus, lycopodium clavatum, turtle shell, scalded rhizoma cibotii, caulis spatholobi, vine of multiflower knotweed, rhizoma atractylodis, cimicifugae foetidae and pomegranate seed. Wherein the content of the radix polygalae is 5 to 15 parts by weight, the content of the storax is 0.3 to 1 part by weight, the content of the sea horse is 3 to 9 parts by weight, the content of the lycopodium clavatum is 3 to 15 parts by weight, the content of the turtle shell is 9 to 30 parts by weight, the content of the hot rhizoma cibotii is 6 to 15 parts by weight, the content of the caulis spatholobi is 9 to 15 parts by weight, the content of the caulis polygoni multiflori is 9 to 15 parts by weight, and the content of the rhizoma atractylodis is 3 to 12 parts by weight. The content of the rhizoma cimicifugae is 3-15 parts by weight, and the content of the pomegranate seeds is 5-15 parts by weight. The traditional Chinese medicine composition for treating vascular dementia has the effects of tonifying the kidney, nourishing blood, reducing phlegm, dredging collaterals, soothing the nerves and promoting intelligence, and can be used for treating vascular dementia, improving the cognitive ability of patients and improving dementia symptoms. The invention also provides a medicinal preparation for treating vascular dementia.

Description

technical field [0001] The invention relates to traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating vascular dementia. The invention also relates to a traditional Chinese medicine preparation for treating vascular dementia. Background technique [0002] Vascular dementia (VD) is a group of intelligence and cognitive dysfunction syndromes caused by cerebrovascular diseases, and it is one of the common diseases of senile dementia. The onset of VD is relatively clear and potentially preventable. It is also called "reversible dementia". Early diagnosis and early treatment are particularly significant for the improvement or reversal of intelligence. With the aging of the population, the incidence of VD is on the rise, which seriously threatens the health and quality of life of middle-aged and elderly people, and brings long-term pain and burden to patients, families and society. widespread attention. Early use of effective dru...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61P25/28A61K35/586A61K35/60
CPCA61K36/69A61K36/185A61K35/60A61K36/11A61K35/586A61K36/12A61K36/486A61K36/704A61K36/284A61K36/71A61P25/28A61K2236/331A61K2236/333A61K2236/39A61K2300/00Y02A50/30
Inventor 刘旺华李花曾逸笛李金霞凌智肖佳璇乔鹏
Owner HUNAN UNIV OF CHINESE MEDICINE
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