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Application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis

A chicken necrotic enteritis, nutmeg essential oil technology, applied in the field of veterinary medicine, can solve complex, comparative research, no animal model testing and other problems, and achieve the effect of large amount of data and high accuracy

Active Publication Date: 2017-11-24
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, different scoring standards are used, resulting in different scoring systems that cannot be compared with each other
Because the establishment of animal models of chicken necrotic enteritis is relatively complicated, most of the current researches have only been tested in vitro, but not in animal models.
The results of only in vitro tests often cannot truly reflect the prevention and treatment effect of the tested drug on chicken necrotic enteritis

Method used

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  • Application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis
  • Application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis
  • Application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis

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Embodiment Construction

[0053] Chicken necrotic enteritis is an acute digestive tract disease caused by Clostridium perfringens, and it is one of the most important intestinal diseases in chickens. It has caused huge losses to the global poultry industry. With the restrictions on the use of antibiotic growth promoters at home and abroad, the incidence of the disease has increased. Finding a safe and effective new agent is a hot issue in the field of farming today.

[0054] The inventor established an artificial pathogenesis model of chicken necrotic enteritis, and laid the foundation for its in vivo screening. The whole study includes 7 parts 1. Isolation and identification of Clostridium perfringens in chicken feces samples and intestinal tissues of cases of necrotic enteritis; 2. Multi-PCR method for genotype identification of field isolates of Clostridium perfringens; 3. . NetB toxin gene (netB) detection of Clostridium perfringens field isolates; 4. Drug resistance detection of Clostridium perf...

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Abstract

The invention discloses an application of mutmeng essential oil and basil essential oil to prevent necrotic enteritis. Plant essential oil includes mutmeng pure essential oil, basil pure essential oil or mutmeng-basil compound essential oil. The applicant spends one to two years and successfully builds an animal model of the necrotic enteritis. The model is feed with wheat basal diet, and fish meal is added in a later period; clostridium perfringens is adopted to counteract toxic substances independently, and typical pathological changes are obvious; and the previous phenomenon that a coccidium concurrent model and coccidiosis are confused can be excluded. The experiment period is short, and the repeatability is high. In addition to in-vitro experiments, the applicant also takes use of the model to do research on the in-vivo control effect of the plant essential oil, and it is really clear that the plant essential oil has the effects of preventing and curing the necrotic enteritis.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to the application of nutmeg essential oil and basil essential oil in preventing and treating chicken necrotic enteritis. Background technique [0002] Chicken necrotic enteritis was first discovered by Parish (1961), and it is an acute digestive tract disease caused by Clostridium perfringens, which is a common disease in chickens. Caused annual loss of more than 2 billion US dollars to poultry industry all over the world. In recent years, the European Union banned the addition of antibiotic growth promoters to feed, resulting in a large number of outbreaks of necrotic enteritis in the chicken industry in European countries. [0003] Necrotic enteritis usually occurs after 4 weeks of age and occurs in poultry farming areas worldwide (Long J R, 1973). Clinical symptoms include acute clinical symptoms and subclinical symptoms. [0004] Acute clinical signs of necroti...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61K36/185A61P1/00A61P31/04A23K20/00A23K10/30A23K50/75
CPCA61K36/185A61K36/53A23K10/30A23K20/00A23K50/75A61K2300/00
Inventor 彭新宇高彪尹烨华袁明贵徐志宏
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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