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Pharmaceutical composition for treating thrombocytopenia, and preparation method and application thereof

A technology of thrombocytopenia and composition, which is applied in the field of pharmaceutical composition for the treatment of thrombocytopenia and its preparation, can solve problems such as thrombopoietin deficiency, and achieve stable curative effect

Inactive Publication Date: 2012-05-09
CHENGDU KANGHEXIN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] 3. Thrombopoietin deficiency

Method used

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  • Pharmaceutical composition for treating thrombocytopenia, and preparation method and application thereof
  • Pharmaceutical composition for treating thrombocytopenia, and preparation method and application thereof

Examples

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Effect test

example 1

[0144] Example 1: Wang XX, female, 74 years old, had a large subcutaneous purpura of unknown cause. The bone marrow examination in the outpatient department of internal medicine showed 171 megakaryocytes, 35 types, and was diagnosed as thrombocytopenic purpura. Prednisone 30mg / day was given After treatment, after 1 month, the hemorrhage of large sheets of purpura did not alleviate, and the platelets were 25 × 109 / L. Afterwards, the pharmaceutical composition of the present invention was combined with prednisone, and the bleeding symptoms were improved after 1 week. Weeks later, the bleeding symptoms disappeared, platelets increased from 25 to 110×109 / L, PAIgG decreased from 240ng / L to 150ng / L, and immune function, liver and kidney function were normal before and after treatment.

example 2

[0145] Example 2: Lu XX, female, 46 years old, with a course of 3 years, had a splenectomy for treatment, after which there were large areas of purpura and hemorrhage in the skin and mucous membranes, and the platelet count was 41×10 9 / L, PAIgG 190ng / L, bone marrow examination confirmed thrombocytopenic purpura, after taking prescription 2 granules for 30 days, the platelet count increased from 87×10 9 / L, PAIgG increased from 240ng / L to 173ng / L (normal), bleeding symptoms improved, and purpura subsided.

[0146] In summary, the pharmaceutical composition of the present invention is after years of clinical observation and screening, and finally determined that the prescription is Agrimony, Cortex Moutan, Polygonum cuspidatum, Angelica, Rehmannia glutinosa, Radix Astragali, Panax notoginseng, Eclipta chinensis, and Gardenia nine herbs. Decreases work best.

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Abstract

The invention specifically relates to a pharmaceutical composition for treating thrombocytopenia, and a preparation method and application thereof, belonging to the field of Chinese medicines. The invention provides a novel pharmaceutical composition for treating thrombocytopenia, and the pharmaceutical composition is prepared from the raw materials of hairyvein agrimony, cortex moutan radicis, gentrin knotweed, glutinous rehmannia, radix astragali, cape jasmine and pseudo-ginseng, has the functions of nourishing yin, tonifying blood, clearing heat and cooling the blood, and can be used for patients who suffer from bleeding, thrombocytopenia and the like caused by deficiency of yin and hot blood. Application of the pharmaceutical composition enables the purpose of the treating thrombocytopenia to be realized.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating thrombocytopenia, a preparation method and application thereof. Background technique [0002] Thrombocytopenia is a variety of symptoms caused by poor prevention of thrombus formation and bleeding due to decreased platelet count or dysfunction. Clinically, the platelet count is lower than the normal range of 140,000-400,000 / μl, which can be diagnosed as thrombocytopenia. Thrombocytopenia may result from insufficient platelet production, retention of platelets by the spleen, increased platelet destruction or utilization, and dilution, among others. The diagnosis and treatment of common thrombocytopenia are listed below: [0003] 1. Primary immune thrombocytopenia [0004] Patients with primary immune thrombocytopenia show skin purpura all over the body, epistaxis or female menorrhagia, fatigue, pale complexion, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P7/00
Inventor 张弘肖禾曾友志
Owner CHENGDU KANGHEXIN MEDICAL TECH
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