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Application of thyme compound plant essential oil in preventing necrotic enteritis

A technology for chicken necrotizing enteritis and fragrant compound essential oil, which is applied in the field of veterinary medicine, can solve the problems of comparative research, complexity, and the inability of scoring system, and achieves the effect of high accuracy and large amount of data

Active Publication Date: 2017-10-20
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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  • Abstract
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Problems solved by technology

In addition, different scoring standards are used, resulting in different scoring systems that cannot be compared with each other
Because the establishment of animal models of chicken necrotic enteritis is relatively complicated, most of the current researches have only been tested in vitro, but not in animal models.
The results of only in vitro tests often cannot truly reflect the prevention and treatment effect of the tested drug on chicken necrotic enteritis

Method used

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  • Application of thyme compound plant essential oil in preventing necrotic enteritis
  • Application of thyme compound plant essential oil in preventing necrotic enteritis
  • Application of thyme compound plant essential oil in preventing necrotic enteritis

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Embodiment Construction

[0051] Chicken necrotic enteritis is an acute digestive tract disease caused by Clostridium perfringens, and it is one of the most important intestinal diseases in chickens. It has caused huge losses to the global poultry industry. With the restrictions on the use of antibiotic growth promoters at home and abroad, the incidence of the disease has increased. Finding a safe and effective new agent is a hot issue in the field of farming today.

[0052] The inventor established an artificial pathogenesis model of chicken necrotic enteritis, and laid the foundation for its in vivo screening. The whole study includes 7 parts 1. Isolation and identification of Clostridium perfringens in chicken feces samples and intestinal tissues of cases of necrotic enteritis; 2. Multi-PCR method for genotype identification of field isolates of Clostridium perfringens; 3. . NetB toxin gene (netB) detection of Clostridium perfringens field isolates; 4. Drug resistance detection of Clostridium perf...

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Abstract

The invention discloses an application of thyme compound plant essential oil in preventing necrotic enteritis. The plant essential oil contains thyme-nutmeg compound essential oil and thyme-basil compound essential oil. An applicator is successful in constructing an animal model with necrotic enteritis through 1-2 years. For the model, wheat basal feed is used for feeding, and fish meal is added at the later period; clostridium perfringens is adopted for independently attacking toxicity, and the classic lesions is obvious; and the phenomenon of mixing of a previous coccidium concurrent model and coccidiosis can be eliminated. The application disclosed by the invention has the advantages that the test period is short and the repeatability is high. In addition to an in-vitro experiment, the applicator also utilizes the model to study the in-vivo control effect of the plant essential oil to really define the preventing and treating effects of the plant essential oil for the necrotic enteritis.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to the application of thyme compound essential oil in preventing and treating chicken necrotic enteritis. Background technique [0002] Chicken necrotic enteritis was first discovered by Parish (1961), and it is an acute digestive tract disease caused by Clostridium perfringens, which is a common disease in chickens. Caused annual loss of more than 2 billion US dollars to poultry industry all over the world. In recent years, the European Union banned the addition of antibiotic growth promoters to feed, resulting in a large number of outbreaks of necrotic enteritis in the chicken industry in European countries. [0003] Necrotic enteritis usually occurs after 4 weeks of age and occurs in poultry farming areas worldwide (Long J R, 1973). Clinical symptoms include acute clinical symptoms and subclinical symptoms. [0004] Acute clinical signs of necrotizing enteritis: ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/53A61P1/00A61P31/04A23K10/30A23K50/75
CPCA61K36/185A61K36/53A23K10/30A23K50/75A61K2300/00
Inventor 彭新宇高彪袁明贵尹烨华徐志宏
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
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