The invention discloses an automatic adjustment positioning device in a six-dimensional space, which can be used for automatically adjusting and positioning an optical element supporting case; the device comprises a threaded sleeve, an A screw rod, a B screw rod, supports, a joint bearing, bolts, screws, a
washer, worm wheels, worm screws, a bearing, a locking nut, a bearing support, a shaft coupler, a motor frame, a
servo motor, a power source, a computer, a movable plate, a fixed bracket, a vacuum mirror cabinet and six sets of driving components which consist of spiral struts, the worm wheels and the worm screws; the supports at one side of each set of the driving components are arranged on the movable plate, while the supports at the other side thereof are arranged, positioned and fastened on the fixed bracket; the
servo motor is matched and the computer adopts closed-loop parallel control to finish adjustment and positioning of the vacuum mirror cabinet in beam lines of
synchrotron radiation in the space six-dimension, i.e., moving along X-axis, Y-axis and Z-axis and rotating around the X axis, the Y axis and the Z axis. The invention realizes the adjustment of the six-dimensional space, simplifies structure, reduces the load of instruments, is simple and reliable in adjustment, and lowers
processing cost.