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191results about How to "Improve image signal-to-noise ratio" patented technology

System for characterizing manual welding operations

A system for characterizing manual welding exercises and providing valuable training to welders that includes components for generating, capturing, and processing data. The data generating component further includes a fixture, workpiece, at least one calibration devices each having at least two point markers integral therewith, and a welding tool. The data capturing component further includes an imaging system for capturing images of the point markers and the data processing component is operative to receive information from the data capturing component and perform various position and orientation calculations.
Owner:LINCOLN GLOBAL INC

System for characterizing manual welding operations

A system for characterizing manual welding exercises and providing valuable training to welders that includes components for generating, capturing, and processing data. The data generating component further includes a fixture, workpiece, at least one calibration devices each having at least two point markers integral therewith, and a welding tool. The data capturing component further includes an imaging system for capturing images of the point markers and the data processing component is operative to receive information from the data capturing component and perform various position and orientation calculations.
Owner:LINCOLN GLOBAL INC

Bridge crack detection method

The invention discloses a bridge crack detection method. Due to the fact that manual marking has certain subjectivity, the pavement crack detection precision depends on experience knowledge of experts, and experience lacks objectivity in quantitative analysis. The method comprises the following steps: 1, collecting images of a detected bridge floor one by one to obtain a bridge floor image set; 2,splicing images; 3, detecting crack; 4, extracting crack parameter. According to the invention, the image acquisition and processing technology replaces human eyes to complete automatic nondestructive detection of the bridge crack, and has very important practical significance for research of the bridge crack detection technology in a complex terrain environment. On one hand, the construction safety is enhanced, and on the other hand, the operation maneuverability and flexibility are improved. According to the invention, fidelity splicing of multiple groups of bridge deck images is realized,the image splicing precision and efficiency are improved, a working foundation is laid for subsequent bridge crack image detection, and a technical reference is provided for image splicing detection in other fields.
Owner:HANGZHOU DIANZI UNIV

Single-slit spatial carrier shearing speckle interferometry measuring system and measuring method

The invention discloses a single-slit spatial carrier shearing speckle interferometry measuring system and a measuring method. The measuring system and the measuring method are characterized in that laser shot by a laser device passes through a beam expander and then irradiate a measured object in the form of diffusion light, diffuse reflection light on the surface of the measured object sequentially passes through an imaging lens, a slit diaphragm, a 4f system and a Michelson type device to be projected onto a target surface of an CCD camera. The measuring system and the measuring method can carry out nondestructive, full-field, rapid and dynamic measurement for the defects and stress deformation of the surface of the measured object and is convenient for field measurement.
Owner:HEFEI UNIV OF TECH

Cone-beam CT system plate detector image anti-interference calibration method

The utility model discloses an anti-interference correction method of flat panel detector image in cone-beam CT system, which is characterized in that collection parameter is set, the plat panel detector is shielded partially, dark image, blank exposure image and object projection image are collected; average dark field image, gain correction image and bad pixel template image are calculated; dark field correction, dark field fluctuation correction, gain correction, bad pixel correction and gain strip correction are made on the object projection image; the filtering de-noising treatment is made on the object projection image, the object segmentation image is re-constructed by the object projection image. The blank exposure image is reconstructed to be a blank segmentation image, the segmentation correction image is calculated; the segmentation correction is made on the object segmentation image; the filtering de-noising treatment is made on the object segmentation image. The utility model has the advantages that the correction result is obviously better than that of the prior correction calculation method, enabling. to effectively dispose the linear and annular artifacts that can not be eliminated by the prior correction method, moreover image signal-to-noise ratio is higher or equal to the prior level.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Fatigue testing machine and testing method capable of synchronously radiating light source for in-site imaging

The invention provides a fatigue testing machine and testing method capable of synchronously radiating a light source for in-site imaging. According to the composition of the testing machine, a cross at the bottom of a bottom plate is embedded to a synchronous light source radiation platform; a servo motor of the bottom plate is connected with the lower end of a lower clamp on a base of the bottom plate through a cam link mechanism; a semi-annular organic glass inner cover and a semi-annular organic glass outer cover are movably embedded to the upper surface of a cover plate of the base, the organic glass inner cover and the top of the organic glass outer cover are connected with a top cover in an embedded mode, the middle of the bottom face of the top cover is connected with the upper end of a load sensor, and the lower end of the load sensor is connected with an upper clamp; the upper clamp is located over the lower clamp; the servo motor and the load sensor are both electrically connected with a data processing and control device. In the fatigue testing process of the testing machine, synchronous radiation imaging can be performed on fatigue testing samples, and a three-dimensional image in a material is obtained; the mechanical properties of materials and the evolution rule of a microscopic structure can be more clearly and accurately reflected.
Owner:SOUTHWEST JIAOTONG UNIV

Method for detecting ultrasonic phased array through combination of transversal and longitudinal waves

The invention relates to a method for detecting an ultrasonic phased array through combination of transversal and longitudinal waves. The method comprises: according to ultrasonic transducer array parameters and wedge parameters, calculating transmission time-delay and reception time-delay of a focus of a large-angle area based on the sound velocity of a transversal wave; transmitting and receiving a sound wave by array elements in the array according to the obtained transmission time-delay and reception time-delay in the large-angle area; forming a focused beam to obtain ultrasonic radio frequency scanning line data of the large-angle area; detecting a small-angle area in a manner of combination of transversal and longitudinal waves, and calculating transmission time-delay and reception time-delay of a focus of the small-angle area; transmitting and receiving a sound wave by the array elements in the array according to the obtained transmission time-delay and reception time-delay in the last step in the small-angle area; forming a focused beam to obtain ultrasonic radio frequency scanning line data of the small-angle area; and transforming and splicing the ultrasonic radio frequency scanning line data of the large-angle area and the small-angle area to obtain an ultrasonic phased array image.
Owner:INST OF ACOUSTICS CHINESE ACAD OF SCI +1

Fundus imaging equipment for clinical diagnosis

InactiveCN102885612AOvercome only single shotOvercoming the inability to obtain video fundus imagesOthalmoscopesDiseaseEyepiece
The invention discloses fundus imaging equipment for clinical diagnosis. The fundus imaging equipment for the clinical diagnosis consists of a light source component, a two-dimensional scanning component, a relay lens component, a detector component and a field-of-view target component. According to the fundus imaging equipment for the clinical diagnosis, an observation direction of a patient is fixed by utilizing the field-of-view target component, a retina of a human eye is scanned by using the two-dimensional scanning component, the detector component and an optical amplifier of the detector component optically enlarge a signal reflected by the retina to enhance the signal-to-noise ratio of an image, and a high-resolution image of the retina is acquired through the detection of a confocal signal; according to the fundus imaging equipment for the clinical diagnosis, the influence of field curvature and aberration in an imaging view field is reduced by the special design of a wide-field lens of the relay lens component, and the wide-field imaging of 30 to 60 degrees is realized by adjusting an eyepiece; high-resolution fundus imaging equipment which is compact is design and is applicable to the clinical diagnosis is fulfilled by the schemes of light source fiber input and optical signal fiber output, so that the imaging quality of the traditional fundus photography system is greatly improved, the imaging view field is greatly increased, and the clinical operability of equipment is strengthened; and the fundus imaging equipment for the clinical diagnosis particularly can acquire high-resolution images of retinas of human eyes under the condition that the retinas reflect weak signal light, and is used for the clinical diagnosis of fundus diseases.
Owner:SUZHOU MICROCLEAR MEDICAL INSTR

Method of Utilization of High Dielectric Constant (HDC) Materials for Reducing SAR and Enhancing SNR in MRI

Layers or coats of materials with high dielectric constant or permittivity with very low conductivity are inserted in between radiofrequency (RF) coil or coil's conductive elements and the sample to enhance the signal to noise ratio (SNR), improve image contrast, and reduce the specific absorption rate (SAR) of magnetic resonance imaging or magnetic resonance spectroscopy instruments. The embodiments of the present invention can be used as an auxiliary device to the standard pre-constructed RF coils or incorporated with RF coil constructions for enhancing RF coil performances in both transmission and reception.
Owner:YANG QING X

A Real-time Detection Method of Infrared Moving Target Based on Adaptive Estimation of Background

The invention discloses a method for detecting an infrared motion target in real time for background adaptive estimation. The method comprises the following steps of: (1) initializing a background model BG (0); (2) inputting a kth-frame original infrared image Xorg (k), wherein k is equal to 1, 2 to K; (3) restraining a space domain non-uniformity noise and a time domain random noise of the kth-frame original infrared image Xorg (k), and outputting an image Xdeal (k) which is subjected to noise restraint; (4) registering the image Xdeal (k), and outputting a registered kth-frame infrared image Xreg (k); (5) updating the background model, namely updating a background model BG (k) of the kth-frame infrared image by using an adaptive forgetting factor method; (6) performing difference operation on the kth-frame infrared image Xorg (k) and the background model BG (k), and outputting a difference operation result Xout (k); and (7) calculating the optimum segmentation threshold value Thopt of a target and a background in the Xout (k) according to a maximum inter-class variance theory to finish detection of the motion target. The method has the advantages that: by image pro-processing, the problem of over-sensitivity in noise and scene change in the conventional background difference method is effectively solved, and the detection probability of the target is improved.
Owner:THE 28TH RES INST OF CHINA ELECTRONICS TECH GROUP CORP

Common-path interference self-adaption optical OCT retinal imaging instrument

The invention discloses a common-path interference self-adaption optical OCT retinal imaging instrument which comprises a beacon light source, an imaging light source, spherical reflectors, a wavefront correction device, a horizontal scanning galvanometer, a vertical scanning galvanometer, a center reflection edge transmission spectroscope, a wavefront sensor, a detector, an AO control system, an OCT control system, a computer, a wavefront controller and the like. The center reflection edge transmission spectroscope is arranged at the conjugate position of the pupil plane of a human eye. The diameter of the reference light beams formed through center reflection is smaller, the aberration introduced by the wavefront correction device after the reference light beams come and go twice is smaller and can be neglected; the aberration generated when sample light beams formed by edge transmission are illuminated into human eyes can be detected and corrected by the AO system. The interference spectrum formed by the light beams can rebuild high-resolution retinal images. The common-path interference self-adaption optical OCT retinal imaging instrument has the advantages of being resistant to environment interference, free of polarization adjustment, simple in dispersion compensation, capable of inhibiting corneal reflection stray light signals and reducing appearance size and lowering cost, suitable for long-optical-path AO-OCT systems and the like.
Owner:INST OF OPTICS & ELECTRONICS - CHINESE ACAD OF SCI

Methods for fat quantification with correction for noise bias

Methods are disclosed for calculating a fat fraction corrected for noise bias of one or more voxels of interest using a magnetic resonance imaging (MRI) system. A plurality of image data sets are obtained each corresponding to NMR k-space data acquired using a pulse sequence with an individual associated echo time tn. A system of linear equations is formed relating image signal values to a desired decomposed calculated data vector having a component such as a water and fat combination having zero mean noise, or having a real fat component and a real water component. A fat fraction is calculated from at least one component of the decomposed calculated data vector. In another embodiment, the system of linear equations is normalized and can directly estimate a fat fraction or a water fraction having reduced noise bias.
Owner:GENERAL ELECTRIC CO +1

Biological thiol fluorescent probe as well as preparation method and application thereof

The invention discloses a biological thiol fluorescent probe. According to the biological thiol fluorescent probe, a first fluorophore is used as an energy donor for emitting fluorescence, and a second fluorophore or quenching group is used as an energy acceptor for absorbing fluorescence. The biological thiol fluorescent probe has the structure of R-S-S-R', wherein R comprises the first fluorophore, and the R' comprises the second fluorophore or quenching group. The invention further provides a preparation method and an application of the biological thiol fluorescent probe. The biological thiol fluorescent probe uses the fluorescence intensity per se to attenuate or quench, thus the imaging signal to noise ratio is increased. In addition, the biological thiol fluorescent probe has high fluorescence stability after the thiol is subjected to reaction. The biological thiol fluorescent probe is easy to prepare and can be prepared at normal temperature and pressure and neutral pH value.
Owner:SHENZHEN INST OF ADVANCED TECH

Internal calibration network unit for reflective surface satellite-borne SAR system and internal calibration method

The invention relates to an internal calibration network unit for an SAR system and an internal calibration method matched with the internal calibration network unit, and realizes internal calibrationof an ultra-wideband reflective surface satellite-borne SAR by adding the internal calibration network unit in the SAR system. According to the invention, a purpose of improving an SAR imaging effectis achieved by correcting a channel deviation to increase a signal-to-noise ratio of an SAR image; calibration of magnitude-phase characteristics of all transmitting channels and receiving channels can be realized by using an internal calibration network; firstly, phase calibration is performed by transmitting dot frequency pulse signals to ensure phase consistency; and then, channel magnitude-phase characteristics of sweep-frequency pulse signals are transmitted to ensure accuracy of the calibration.
Owner:XIAN INSTITUE OF SPACE RADIO TECH

Benzylidene indandione compound and preparation thereof and application in specific imaging of lipid droplet

The invention belongs to the field of medical materials, and discloses a benzylidene indandione compound and a preparation thereof and an application in specific imaging of a lipid droplet. The structure of the benzylidene indandione compound is as shown in a formula I. The benzylidene indandione compound has the advantage of aggregation-induced emission, and the defects of aggregation-induced quenching of a traditional fluorescent dye can be effectively overcome, so that the specific fluorescence imaging of the lipid droplet in a living cell can be achieved; furthermore, the benzylidene indandione compound has a two-photon absorption cross-section which is high in living cell penetration rate, high in signal to noise ratio, small in cytotoxicity, large in stokes shift and large in near infrared region. The formula I is as shown in the specification.
Owner:SOUTH CHINA UNIV OF TECH

Adaptive image target enhancement method based on difference of Gaussian model

The invention discloses an adaptive image target enhancement method based on a difference of Gaussian model and belongs to the digital image processing field. In the method, based on a lateral inhibition phenomenon of a biological visual receptive field, the difference of Gaussian (DOG) model of image space domain filtering is established. Target and noise gray level distribution prior knowledge in a water surface image and a constraint relation of excitability and inhibition effect offset are used to select a model parameter so as to reach a local optimal enhancement effect. By using the method in the invention, comprehensive performance of target enhancement, background inhibition and noise filtering is better than the comprehensive performance of a traditional spatial-domain high pass filter. The enhanced image possesses a good visual sense and simultaneously a demand of subsequent motion vector estimation to a correlation operation signal to noise ratio is satisfied.
Owner:HOHAI UNIV

Method for detecting cracks in bridge image

The invention discloses a method for detecting cracks in a bridge image. Due to the fact that manual marking has certain subjectivity, detection precision depends on experience knowledge of experts, and experience lacks objectivity in quantitative analysis. The method comprises the following steps: 1, detecting the position of a crack in a bridge floor image, and completely extracting the morphological characteristics of the crack; 2, extracting real parameters of cracks in the image. According to the invention, an image processing technology is used to replace human eyes to complete automaticnondestructive detection of bridge cracks. Aiming at the unique spatial ductility and gray distinguishability of bridge cracks, the improved median filtering algorithm is provided, according to the characteristics of crack edge similar gray linear distribution, on the basis of original median filtering, the thought of the similar gray scale extension direction is introduced, interference of bridge floor image composite noise can be restrained more effectively, the signal-to-noise ratio of the image is increased, the continuity of detail information of the crack edge is kept, and the reliability of fidelity filtering of a target crack is improved.
Owner:HANGZHOU DIANZI UNIV

Shortwave infrared fluorescence microimaging method

The invention discloses a shortwave infrared fluorescence microimaging method. A near-infrared light source or a visible light source is used as a light source for exciting a shortwave infrared fluorescence probe, the excitation light source converges on a shortwave infrared fluorescent sample through an objective lens and excites fluorescence, the fluorescence is collected by the objective lens and goes through a beam splitter to separate excitation lights and a fluorescence signal, only the fluorescence signal reaches a shortwave infrared camera, and the shortwave infrared camera transmits a video signal to a computer in order to realize real-time shortwave infrared imaging. Tomographic fluorescence imaging of different depths of the sample can be obtained by adjusting the relative position of the fluorescent sample and the objective lens. Compared with the traditional fluorescence microscopy methods in the visible light band, the method disclosed in the invention has the advantages of large biological tissue penetration depth and small biological damage; and compared with shortwave infrared fluorescence macroimaging methods, the method disclosed in the invention has the advantages of high imaging resolution, high imaging magnification factor, video microimaging realization and tomographic fluorescence imaging realization.
Owner:ZHEJIANG UNIV

Weak target detection device and method for dual-band imaging correlation full-spectrum measurement

ActiveCN106932097AImprove image signal-to-noise ratioImproving the Ability of Recognizing Weak Targets in Remote Sensing Infrared DetectionSpectrum investigationOptical detectionDistortionWave band
The invention discloses a weak target detection device and method for dual-band imaging correlation full-spectrum measurement. The device comprises an ultraviolet visible-light and infrared optical window, a large-field-of-view two-dimensional scanning rotating mirror, a common-aperture main optical system, an infrared imaging spectrum optical subsystem module, a visible and near-infrared imaging spectral optical sub-system module, an ultraviolet spectral optical subsystem module, a medium-wave large-field-of-view detector, a medium-wave infrared middle-view-field detector, an infrared non-imaging wide-spectrum spectral measurement system, a visible near-infrared large-field-of-view detector, a visible near-infrared middle-view-field detector, a visible near-infrared spectrum measurement system, an ultraviolet spectrum measurement unit, a multi-mode coordination information processing, and control module, a control module and a servo system. In addition, according to the method, a target background optical field is filtered; multi-scale coupling matching is carried out on distortion target radiation field multi-dimensional information; and multi-scale target detection information is utilized comprehensively to achieve objectives of precise target detection and identification and information inversion; and thus a problem that a weak target can not be detected in conventional remote-sensing detection can be solved.
Owner:NANJING HUATU INFORMATION TECH

Biological fluorescence microscopic detection instrument

The invention provides a biological fluorescence microscopic detection instrument which comprises an excitation light illumination unit, excitation light, a fluorescence isolation unit, a reflecting unit, a microimaging unit, a fluorescence detection unit, a precision displacement platform and a control unit. An illumination pinhole is arranged between a first beam expander and a second beam expander of the excitation light illumination unit and located at a focal point of the first beam expander, an imaging detection pinhole is arranged between an imaging lens and a photomultiplier of the fluorescence detection unit and located at a focal point of the imaging lens, and therefore, the transverse resolution of the instrument is effectively improved; meanwhile, an annular beam shaping assembly is arranged between a tube lens and a microobjective of the microimaging unit, which enables the axial resolution of the biological fluorescence microscopic detection instrument to be improved.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH

Metal material industrial CT image quality rapid correction method

Provided is a metal material industrial CT image quality rapid correction method. The method is characterized in that the method includes following steps: 1) reading a CT image with noise and ring artifact; 2) mapping the CT image read in step 1) to a polar coordinate from a rectangular coordinate, and forming a polar coordinate image; 3) calculating a filtering parameter (Sr) according to the polar coordinate image; 4) performing ring artifact filtering processing on the CT image by employing the filtering parameter (Sr) obtained in step 3) to obtain a CT image which removes the ring artifact; and 5) performing de-noising processing on the CT image which removes the ring artifact to obtain the corrected CT image. The method is used for reconstructing the post-CT image, parameter correction and automatic calculation are realized, the calculating efficiency is high, image details are saved to the maximum, the method is applicable to post-processing of a lot of industrial CT system images in the market, the image signal to noise ratio is increased, especially high-energy linear array industrial CT, the correction effect is good, and the market promotion value is good.
Owner:CHINA WEAPON SCI ACADEMY NINGBO BRANCH

Improved actuation mechanism for fatigue testing machine achieving in-situ imaging of synchrotron radiation light source

The invention discloses an improved actuation mechanism for a fatigue testing machine achieving in-situ imaging of a synchrotron radiation light source. The actuation mechanism is arranged on a cylinder-shaped base plate on a platform of the synchrotron radiation light source and used for applying a vertical reciprocating displacement load to a test sample on the fatigue testing machine achieving in-situ imaging of the synchrotron radiation light source. Compared with the last generation of fatigue testing machines, further improvement is conducted, friction generated by a cam actuation mode is reduced, therefore, energy consumption of the fatigue testing machine is reduced, and the noise reduction performance of the fatigue testing machine is further improved; the load applied to the test sample is further guaranteed, and compared with the last generation of the fatigue testing machines, the details in the test implementation process are considered more detailedly.
Owner:SOUTHWEST JIAOTONG UNIV

Transient multispectral polarization imaging device and imaging method thereof

The invention discloses a transient multispectral polarization imaging device and an imaging method thereof. The transient multispectral polarization imaging device comprises an imaging objective lens, a diaphragm, a collimating objective lens, an optical filter array, a micro lens array and an area array detector which are arranged successively. The imaging method comprises the following steps that: an incident light is imaged on the diaphragm through the imaging objective lens and then is incident to the optical filter array in the form of a collimated light beam through the collimating objective lens; the collimated light beam is divided into a plurality of collimated light beams with different wave bands, the plurality of collimated light beams are incident to the micro lens array, wherein the positions of optical filters are in one-to-one correspondence with the positions of micro lenses; the multiple collimated light beams are respectively imaged in different areas of a target surface of the area array detector through the micro lens array, images on the area array detector are collected, and spectral polarization images of multiple wave bands are obtained; and a color spectral polarization image is synthesized through adoption of the acquired spectral polarization images of the plurality of spectral bands. The transient multispectral polarization imaging device can realize synchronous real-time measurement for spectral information and polarization information of a detected target, and has the advantages of compact structure, low complexity, high integration level, high measurement efficiency and the like.
Owner:NANJING UNIV OF SCI & TECH

Multi-mode infrared imaging system and method facing weak target detection

The invention discloses a multi-mode infrared imaging system and method facing weak target detection. The system is composed of an infrared optic window, a large-view-field two-dimensional scanning rotating mirror, a Cartesian reflector group, a broad-spectrum relay lens, a first lens group, an adjustable space variable-transmittance lens, a second lens group, an FPA module, a data processing module, and a space addressable transmittance modulation module. The data processing module generates a transmittance modulation control signal and an imaging integral time modulation signal according to an image data signal outputted by the FPA module; the adjustable space variable-transmittance lens adjusts a light field transmittance dynamically under the effect of the transmittance modulation control signal; and the FPA module adjusts the imaging integral time adaptively under the effect of the imaging integral time modulation signal. On the basis of adjustment, an imaging signal to noise ratio of a weak signal is improved. A target light filed and a background light field are adjusted to linear parts of an infrared imaging sensor response curve; and thus an objective that a weak target can be identified under the circumstances that the luminous flux is not sufficient or the luminous flux is too high.
Owner:NANJING HUATU INFORMATION TECH

Magnetic resonance imaging method and device achieving water/fat separation

In a magnetic resonance imaging method and apparatus for water / fat separation, a turbo spin echo BLADE (TSE BLADE) artifact correction sequence is executed to acquire original data for an in-phase image and original data for an opposite-phase image, and an in-phase image on the basis of the original data for the in-phase image and an opposite-phase image on the basis of the original data for the in-phase image and the original data for the opposite-phase image are reconstructed. Water and fat images are calculated on the basis of the reconstructed in-phase image and opposite-phase image. By using a TSE BLADE sequence to acquire k-space data, the advantage of the BLADE sequence of being insensitive to rigid body motion and pulsation is inherently present, thereby reducing sensitivity to motion artifacts while improving the image signal-to-noise ratio.
Owner:SIEMENS HEALTHCARE GMBH

Cavitation micro-bubble high signal-to-noise ratio ultrasonic rapidly imaging and dynamic dimension distribution estimating method

The invention provides a cavitation micro-bubble high signal-to-noise ratio ultrasonic rapidly imaging and dynamic dimension distribution estimating method, comprising: (1) building a cavitation micro bubble wavelet under a static state starting condition; (2) acquiring information of backscatter Intensity change along time in a solution and in a source energy irradiation volume by a full-digitization ultrasonic two dimension planar-array energy transducer and by a plane wave emission and reception manner, and carrying out micro bubble wavelet transformation on it to raise cavitation micro bubble imaging signal-to-noise ratio; (3) acquiring a radius of micro bubble with a maximum number in a cavitation micro bubble group; (4) dividing a cavitation micro bubble area into sub-areas with a same size, to obtain brightness corresponding to the micro bubble with the maximum number in each sub-area, thereby obtaining dimension distribution of the whole cavitation micro bubble group; and (5) obtaining volume distribution of cavitation micro bubble dimensions under a flow state. The method of the invention carries out cavitation micro bubble wavelet transformation, obtains signal-to-noise ratio enhanced cavitation micro bubble images, and simultaneously, completely dynamic estimation on the cavitation micro bubble dimensions.
Owner:XI AN JIAOTONG UNIV

Label-free microfluidic cell instrument and method based on light sheet illumination and sheath flow technology

ActiveCN108444897AImprove the signal-to-noise ratio of light scattering detectionFast imagingIndividual particle analysisWater dynamicsSignal-to-noise ratio (imaging)
The invention discloses a label-free microfluidic cell instrument and method based on a light sheet illumination and sheath flow technology, and the method is as follows: a laser beam shaping module generates a laser light sheet to be incident into a sheath flow generation control module, the sheath flow generation control module forms a sheath flow effect by a water dynamic focusing effect, the incident laser light sheet from the laser beam shaping module is coupled with a focused sample stream under the sheath flow effect to excite to-be-tested particles or cells fast flowing in the sample stream to undergo light scattering, and a two-dimensional light scattering image of the to-be-tested particles or cells is captured by an imaging acquisition module and sent to an image processing system for data analysis and result output. A sheath flow machine can be fasted formed by a novel sheath flow technology without complicated micromachining operation; by the coupling of the light sheet illumination technology and the sheath flow technology, the light scattering detection signal to noise ratio can be improved, and label-free fast imaging of the flowing particles or cells can be realized. High-precision particle size recognition in a flow state can be realized by a particle size identification method based on Euclidean distance for matching degree query.
Owner:SHANDONG UNIV

PH (potential of hydrogen)-responsive type ultra-sensitive nanometer fluorescent probe and method for preparing same

The invention belongs to the field of molecular imaging technologies, and discloses a pH (potential of hydrogen)-responsive type ultra-sensitive nanometer fluorescent probe and a method for preparingthe same. The pH-responsive type ultra-sensitive nanometer fluorescent probe comprises pH-responsive matrix materials and fluorescent organic small-molecule dye. The pH-responsive matrix materials comprise calcium phosphate, hydroxy calcium phosphate, fluorapatite, calcium carbonate and ZIF series; the fluorescent organic small-molecule dye is positively charged dye or negatively charged dye. Themethod includes coating the positively charged dye with the negatively charged matrix materials; coating the negatively charged dye with the negatively charged matrix materials; coating the negativelycharged dye with the positively charged matrix materials. The pH-responsive type ultra-sensitive nanometer fluorescent probe and the method have the advantages that the fluorescent imaging sensitivity and specificity can be greatly improved as compared with the traditional small-molecule fluorescent dye, and response of tumor micro-environments can be detected in an ultra-sensitive manner; the pH-responsive type ultra-sensitive nanometer fluorescent probe which is a specific responsive probe prepared for unique properties of the tumor micro-environments is high in targeting, few in backgroundsignals and high in signal-to-noise ratio, small tumor can be detected in an ultra-sensitive manner, and the like.
Owner:XIDIAN UNIV

Air-coupled ultrasonic imaging method based on wavelet analysis and related algorithms

The invention discloses an air-coupled ultrasonic imaging method based on wavelet analysis and related algorithms. Imaging is carried out by using wavelet coefficients of a sub-band and related coefficients of a reference signal as characteristic quantities, enabling effective elimination measurement-induced white Gaussian noise and strength fluctuation noise of air-coupled ultrasonic transmitting signals and improving signal to noise ratio of an image. Meanwhile, whether small size defects exist or not is judged through minimum values of related coefficients, thus adaptively adjusting a smooth filter window, the size of the smooth window is enlarged upon a large defect size, thereby reducing background noise, the size of the window is reduced upon a small defect size, highlighting signal details and thereby implementing 'adaptive focusing' and improving the ability to detect small defects. The imaging method has a promising application prospect in the field of air-coupled ultrasonic detection.
Owner:GUANGDONG INST OF INTELLIGENT MFG

Methods for fat quantification with correction for noise bias

Methods are disclosed for calculating a fat fraction corrected for noise bias of one or more voxels of interest using a magnetic resonance imaging (MRI) system. A plurality of image data sets are obtained each corresponding to NMR k-space data acquired using a pulse sequence with an individual associated echo time tn. A system of linear equations is formed relating image signal values to a desired decomposed calculated data vector having a component such as a water and fat combination having zero mean noise, or having a real fat component and a real water component. A fat fraction is calculated from at least one component of the decomposed calculated data vector. In another embodiment, the system of linear equations is normalized and can directly estimate a fat fraction or a water fraction having reduced noise bias.
Owner:GENERAL ELECTRIC CO +1
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