64 results about "Glucomanna" patented technology

A method for promoting weight management in a mammal is provided, comprising administering to the mammal a composition comprising at least one weight loss agent and at least one mitochondria enhancingagent. The weight loss agent may be selected from the group consisting of psyllium, guar gum, capsaicin, chitosan, caffeine, garcinia cambogia, Pinus densiflora, capsaicin, yohimbre, hoodia, glucomannan, African mango, guarana, pyruvate, carnitine, beta-glucan, fucoxanthin, raspberry ketone, white kidney bean, kola nut, chromium, ginseng, psyllium, St. John's wort, dandelion, hydroxycitric acid,conjugated linoleic acid, green tea, black tea, green coffee beans extract, forskolin and bitter orange. The mitochondria enhancing agent may be selected from the group consisting of beetroot extract,nitrate, idebenone, nicotinamide riboside, elamepratide, vitamin C, vitamin D, vitamin E, thiamine, riboflavin, magnesium, calcium, phosphate, phospholipid, creatine, pyruvate, coenzyme Q10, NADH, nicotinic acid, L-camitine, dicholoracetate, curcumin, schisandrin and resveratrol. Compositions for weight management are also provided.

The invention relates to a cellular purified konjac glucomannan gel food and a processing method thereof. According to the invention, konjac tofu is upgraded into the cellular purified konjac glucomannan gel by changing the compact structure of the konjac tofu into a cellular tissue structure, removing konjac starch and reducing the pH value of the konjac tofu to 7.0+ / -0.1. The method comprises the following steps of: preparing alkali liquid; adding and spreading konjac powder into the alkali liquid; stirring sol and carrying out deacetylation reaction on glucomannan; heating and curing the gel for forming; dicing and rinsing the gel; soaking and cooking the gel by boiled water; carrying out preservative treatment on the gel; and sealing and packaging the gel. The cellular purified konjac glucomannan gel food has a cellular tissue structure, is colorless, odorless, crisp, refreshing and thermally irreversible, and has better mouth feel in comparison with the conventional konjac tofu. Due to the cellular tissue structure, the cellular purified konjac glucomannan gel food is good in permeability and soup taste adsorbability and wide in cooking adaptability, and thus the social utility value of konjac glucomannan is improved.

The invention designs a preparation method of a feed mycotoxin adsorbent. A main component namely konjac glucomannan of konjac refined powder is subjected to esterifying modification with sodium hexametaphosphate, so that esterified konjac glucomannan is synthetized, and the prepared esterified konjac glucomannan is subjected to characterization, so that the chemical structure of the esterified konjac glucomannan is deduced. According to the preparation method disclosed by the invention, further the synthetized esterified konjac glucomannan is used as the feed mycotoxin adsorbent, and common mycotoxin is subjected to adsorption research. Compared with the prior art, the preparation method disclosed by the invention is simple and convenient to operate, can be applied to large-scale production, and has favorable social and economic benefits; and the esterified konjac glucomannan is used as the feed mycotoxin adsorbent, the adsorption effect of the esterified konjac glucomannan is obviously better than that of an adsorbent namely mycosorb which is frequently used at present, and the preparation method has important significance on an application of plant source esterified glucomannan in feed additives.

The invention discloses a method for preparing high-purity glucomannan. The method comprises main steps as follows: a solution with the concentration of 0.5%-10.0% is prepared from homogeneous polysaccharide raw materials which have the molecular weight in a range of 10-1,000 kD and are selected from naturally sourced konjac polysaccharides, Bletilla striata polysaccharides or hydrolysates of the konjac polysaccharides or Bletilla striata polysaccharides; a filter aid is added to the solution for treatment, an obtained mixture is filtered and is sequentially filtered with a 100-1,000-nm micro-filtration membrane and concentrated with an ultrafiltration membrane with the molecular weight cut off of 2-100 kD, an obtained product is concentrated and dried, and the high-purity glucomannan with the purity of 90% or higher or a liquid preparation of the high-purity glucomannan is obtained. The method has the advantages that the preparation process is concise and controllable, and enlarged production is realized easily; the obtained glucomannan has high purity and low content of related substances and can meet the quality standard for medicinal bulk pharmaceutical chemicals, thereby being applicable to preparation of drugs and related medical products such as pharmaceutical excipients, medical equipment and the like.

The invention discloses novel injectable hydrogel for bone defect repair. A preparation method of the novel injectable hydrogel comprises the steps: 1, preparing bioactive glass; 2, preparing hydrazide bond-grafted collagen and modified oxidized konjac glucomannan; 3, dispersing the bioactive glass and the hydrazide bond-grafted collagen in a PBS solution to obtain a solution A; dissolving the modified oxidized konjac glucomannan in a PBS solution to obtain a solution B; and 4, mixing the solution A and the solution B to obtain the novel injectable hydrogel for bone defect repair. The novel injectable hydrogel for bone defect repair has the advantages that in-situ injection can be achieved, operation is easy and convenient, secondary injury generated by an operation is small, the hydrogel can adapt to the shape of a defect part, in-situ filling forming of the bone defect part is achieved, and the application prospect is wide.

The invention provides a temperature-sensitive gel for gynecological antibacterial nursing. Based on the total amount of the temperature-sensitive gel for gynecological antibacterial nursing, the temperature-sensitive gel comprises the following components in percentage by weight: 1.2%-17% of a humectant, 0.2%-0.5% of chlorhexidine acetate, 1.11%-9.4% of a traditional Chinese medicine antibacterial compound, 16%-30% of a temperature-sensitive gel, 3.2%-5.2% of a freshener and 0.3%-0.6% of a preservative, 0.3%-5.05% of a lubricant and 46.07%-61.7% of deionized water, and the temperature-sensitive gel is any two of glucomannan, poloxamer 407 and poloxamer 188. Through combination of the chemical bacteriostatic agent and the main bacteriostatic agent, the gynecological antibacterial temperature-sensitive gel has a more milder and more thorough antibacterial effect, the gelation temperature can be adjusted, the gel is convenient to use and more suitable for human body, and all the components are safe and reliable, and the gel is free of irritation to the human body and free of accumulated toxicity.

The invention discloses modified hydroxypropyl chitosan adhesive self-healing hydrogel as well as a preparation method and application thereof. The preparation method comprises the following steps of: chemically modifying hydroxypropyl chitosan with caffeic acid; performing modifyingwith composite acrylamide; performing cross-linking with a mixed cross-linking agent of oxidized konjac glucomannan and N, N '-methylene bisacrylamide; and finally preserving heat to obtain the modified hydroxypropyl chitosan adhesive self-healing hydrogel. The hydrogel has excellent adhesion, self-healing, mechanical and swelling properties. By introducing the acrylamide, the adhesion property of the adhesive self-healing hydrogel is improved to 2.66 times, and the mechanical property of the adhesive self-healing hydrogel is improved to 2.4 times. With the hydrogel of the invention adopted, the problems of insufficient adhesion, self-healing and mechanical properties of a traditional hydroxypropyl chitosan hydrogel are solved.

The invention discloses a urea detection kit, and belongs to the technical field of clinical in-vitro detection reagents. The kit comprises a reagent R1, a reagent R2 and a calibration material. A compound stabilizer composed of 4-FPBA, glucomannan, NaCl, propylene glycol, triton X-100 and BSA is added in the reagent R2, so that the stability of the kit is effectively improved, the linearity range is relatively good, the reagent accuracy is high, and further popularization and application in the market are facilitated.

Nutritional rice noodles and a preparation method thereof are disclosed by the invention. Rice and long-shaped rice are taken as main raw materials, meanwhile, hydroxypropyl distarch phosphate, walnut peptide, wheat dietary fibers and konjac glucomannan are added, so that the quality of the rice noodles is remarkably improved, the rice noodles have good elasticity, smoothness and hardness, and the breaking rate and the cooking loss rate of the rice noodles are reduced. The nutritional rice noodles provided by the invention are rich in nutrient substances, and the plant extract is added to prolong the preservation time of plants and improve the aging resistance of the rice noodles. The whole preparation method of the nutritional rice noodles is simple and convenient in process, easy to operate and suitable for batch production.

The invention discloses a preparation method of alcohol-induced low-alkali konjak gel. The method comprises the following steps: 1) preparing konjac glucomannan sol (hereinafter referred to as konjacsol); 2) adding alkali into the obtained sol, and uniformly stirring the sol; 3) adding absolute ethyl alcohol into the mixture obtained in the step 2), and uniformly stirring the mixture; and 4) carrying out constant-temperature treatment on the mixture obtained in the step 3) to prepare the konjak gel. The konjak gel is formed by adding ethanol under the condition of extremely low alkali contentthrough induction. According to the method, ethanol is additionally added, so that the use amount of alkali is reduced; the gelatinization temperature of the konjac gel and the swelling ratio of thekonjac gel are reduced; the white opaque brittle konjak gel is formed through induction by the method disclosed by the invention.

The invention discloses a konjac glucomannan separation method and device. The konjac glucomannan separation method comprises the following steps of: pre-treating, separating, drying and cooling and post-treating. The device comprises a rack platform, a power distribution cabinet, continuous rolling and separation equipment and an alcohol metering container, wherein the rack platform is provided with the power distribution cabinet, the continuous rolling and separation equipment and the alcohol metering container; the continuous rolling and separation equipment is connected with a power grid of the power distribution cabinet; the continuous rolling and separation equipment comprises a feeding pot, cyclone separation devices, liquid discharging pipelines, a material pumping pipeline, waste material discharging pipelines and a waste material collecting device; the feeding pot is provided with the waste material discharging pipelines; the waste material discharging pipelines are connected in series through the cyclone separation devices. According to the konjac glucomannan separation method and device disclosed by the invention, the activity is guaranteed while the content of konjac glucomannan is improved; the content of sulfur dioxide in the konjac glucomannan is reduced; after the separation, the viscosity of konjac fine powder is greatly improved.

The invention discloses a glucose detection kit and belongs to the technical field of clinical in-vitro detection reagents. The kit comprises a reagent R1, a reagent R2 and a calibrator. A composite stabilizer prepared from 4-FPBA, glucomannan, NaCl, propylene glycol, triton100 and BSA is added into the reagent R2, so that the stability of the kit is effectively improved, the linear range is better, the reagent accuracy degree is high, and the glucose detection kit is beneficial to being used and popularized further in the market.

The present compositions and methods relate to a beta-mannanase from Mahella australiensis, polynucleotides encoding the beta-mannanase, and methods of make and / or use thereof. Formulations containing the beta-mannanase are suitable for use in hydrolyzing lignocellulosic biomass substrates, especially those comprising a measurable level of galactoglucomannan (GGM) and / or glucomannan (GM).

The invention provides moisturizing mask liquid which is prepared from, by weight, 10-15 parts of casein antibacterial peptide, 50-70 parts of ceramide, 10-20 parts of pyrrolidone carboxylic acid, 10-20 parts of lactic acid, 30-50 parts of konjac glucomanna, 1-5 parts of antioxidant, 1-3 parts of ethylene glycol amine, 0.1-1 part of EDTA disodium, 1-2 parts of carbomer, 1-5 parts of plant essential oil, 10-15 parts of traditional Chinese medicine moisturizing extract and 70-100 parts of deionized water. The moisturizing mask liquid has anti-inflammatory effect, anti-cell-division effect and antipruritic effect, can be used for making skin healthy, can prevent skin diseases, can be used for treating the skin diseases and has wide application prospect.

The invention discloses sprayable hydrogel and a preparation method and application thereof. The preparation method comprises the steps that konjac glucomannan is subjected to oxidation modification with sodium periodate so as to prepare oxidized konjac glucomannan; then gamma-sodium polyglutamate is subjected to acidification and further treatment so as to obtain modified polyglutamic acid; and the sprayable hydrogel is prepared from the oxidized konjac glucomannan and the modified polyglutamic acid. The hydrogel obtained by the preparation method disclosed by the invention is stable in performance and good in ductility, and the technical problems that the gamma-polyglutamic acid cannot be gelatinized, and a gel formed by the konjac glucomannan in water is poor in stability and weak in ductility are solved. The sprayable hydrogel prepared by the preparation method disclosed by the invention can be widely applied to biomedical engineering.

The invention belongs to the technical field of traditional Chinese medicine preparations, and specifically discloses a preparation with the effect of reducing blood glucose and blood fat and a preparation method of the preparation. The preparation mainly comprises the following raw materials in parts by weight: 3 to 10 parts of hawthorn, 5 to 15 parts of Chinese yam, 3 to 5 parts of fruit of Chinese wolfberry, 5 to 15 parts of sweet Chinese catalpa grass, 5 to 20 parts of root of kudzu vine, 10 to 20 parts of gynostemma pentaphylla, 0.1 to 0.5 part of corn stigma, 1 to 3 parts of vernoniaamygdalina del leaves, 2 to 6 parts of butterflybush flower, 0.001 to 0.005 part of eleutheroside, 0.03 to 0.07 part of soy isoflavone, 1 to 5 parts of oxidized konjac glucomannan and 0.05 to 0.5 part offermented soya bean fibrinolytic enzyme. According to the traditional Chinese medicine preparation provided by the invention, the blood viscosity can be effectively improved, the blood glucose and blood fat are reduced, and the metabolic activity of fat is strengthened; partial raw materials come from food, the preparation is safe without side effect, and the preparation is convenient to take andgood in taste; and the preparation can be mixed with flour and buckwheat powder in a certain proportion, so that a health food capable of reducing blood glucose and blood fat is prepared.

The invention brings forward a microsphere carrier, a method for preparing the microsphere carrier, an embedding object, a medicine, a food, and the application of the embedding object in preparing the medicine or the food. The microsphere carrier comprises thiol-modified oxidized konjac glucomannan. The microsphere carrier of the invention has strong stability in gastric juice and high adhesion performance in intestinal tract, so that functional factors embedded on the microsphere carrier have higher bioavailability.

The invention discloses a collagen peptide beverage composition and a preparation method thereof. The beverage composition is prepared from the following components in parts by weight: 70 to 80 parts of purified water, 5 to 10 parts of collagen peptide, 4 to 8 parts of deep-sea fish collagen, 4 to 8 parts of a polysaccharide mixture, 3 to 7 parts of an extract mixture, 0.4 to 0.8 part of probiotics, 2 to 6 parts of konjac glucomannan, 2.5 to 5.5 parts of fruit concentrated juice and 0.8 to 1.6 parts of a food additive. The collagen peptide beverage is prepared by uniformly mixing the purified water, the collagen peptide, the deep-sea fish collagen, the polysaccharide mixture, the extract mixture, the probiotics, the konjac glucomannan, the fruit concentrated juice and the food additive according to a scientific and reasonable ratio, and the preparation method is simple; and under the combined action of the collagen peptide and the deep-sea fish collagen, a human body can absorb the collagen in the drink, so that the skin becomes tender, elastic and free of wrinkles due to the sufficient collagen, and a very good beautifying and skin care effect can be achieved.

The invention discloses a making process of rice noodles. The making process comprises the following steps: by taking rice and long-shaped rice as main raw materials, firstly performing fermentation and enzymolysis pretreatment, then adding auxiliary materials such as hydroxy propyl distarch phosphate, walnut peptide, dietary fiber, konjac glucomannan and the like, and finally performing gelatinization, extrusion and re-steaming to obtain the rice noodles. The rice noodles are rich in nutrition and smooth in taste, the quality of the rice noodles is improved, and the rice noodles are resistant to water boiling and not prone to breakage.

The invention discloses a preparation method and application of internally tangent beta-1,4-glucanase gene derived from paenibacilluspolymyxa and its enzyme. The preparation method is a technique method utilizing genetic engineering. The internally tangent beta-1,4-glucanase gene is cloned to an escherichia coli expression vector to obtain an escherichia coli recombination strain which can heterologously express the enzyme, and the strain heterologously expresses the prepared internally tangent beta-1,4-glucanase and can efficiently degrade konjac glucomannan (also known as konjac glucomanna).The prepared internally tangent beta-1,4-glucanase can be widely applied the fields of preparation of agriculture, foods, feed additives, medicine, oligo-glucomannan and the like.

The invention provides natural antibacterial mask base cloth, a preparation method thereof and a mask. Raspberries are firstly used as raw materials, supercritical CO2 fluid extraction is carried outto obtain a raspberry extract, then the raspberry extract is mixed with deacetylated konjac glucomannan to prepare a spinning solution, and electrostatic spinning is carried out to obtain fibers I; then fullerene is modified with silk fibroin to obtain an intermediate product, then after the intermediate product is mixed with lactic acid, a polymerization reaction is carried out to obtain modifiedfullerene, and melt spinning is carried out to obtain fibers II; and finally, the fibers I and the fibers II are mixed to prepare spunlace non-woven fabric, and the mask base cloth is obtained. The mask base cloth prepared through the method has good liquid retention performance and good antibacterial activity.

A pharmaceutical composition comprising at least one active pharmaceutical ingredient (API) or a pharmaceutically acceptable salt thereof, a glucomannan, a first polyalkylene oxide having an average molecular weight of no more than 300,000, and a second polyalkylene oxide having an average molecular weight of at least 1,000,000 and methods of making. The pharmaceutical composition provides extended release of the API and has abuse deterrent features.

The invention brings forward a microsphere carrier, a method for preparing the microsphere carrier, an embedding object, a medicine, a food, and the application of the embedding object in preparing the medicine or the food. The microsphere carrier comprises thiol-modified oxidized konjac glucomannan. The microsphere carrier of the invention has strong stability in gastric juice and high adhesion performance in intestinal tract, so that functional factors embedded on the microsphere carrier have higher bioavailability.

The invention relates to the technical field of extraction equipment, and discloses an extraction kettle for extracting glucomannan from konjac seeds, the extraction kettle comprises a support frame,wherein an extraction barrel is fixedly mounted on the top of the support frame; a drain pipe is fixedly mounted on the bottom of the extraction barrel; a valve is fixedly sleeved outside the drain pipe; an end cover is fixedly sleeved on the top of the extraction barrel; a stirring motor is fixedly mounted on the top of the end cover; and a stirring device fixedly sleeves one end of an output shaft of the stirring motor extending to the bottom of the end cover. According to the extraction kettle for extracting glucomannan from konjac seeds, the position of an adjusting plate can be adjusted by rotating a nut through the mutual cooperation of an adjusting device and a liquid absorption pipe, and when the adjusting plate moves up and down, the liquid absorption pipe can be driven to move upand down, so that the position of the liquid absorption pipe is adjusted according to the height of the supernatant fluid, and the supernatant fluid is convenient to absorb.

The invention relates to air-dried sausages, and in particular relates to a preparation method of the air-dried sausages. The method comprises the following steps: adding a salt preparation into chopped pig hind leg meat, performing uniform stirring, and performing marinating at 4 DEG C for 4-5 h; adding auxiliary materials, and performing full mixing and uniform chopping, wherein the auxiliary materials include the following components: deacetylated konjac glucomannan and nanofibrillated cellulose; inoculating a mixture of lactobacillus, staphylococcus xylosus and glucose bacteria into the meat material, performing uniform stirring, and performing sausage filling to obtain meat sausages; and uniformly coating the surfaces of the meat sausages with a biofilm solution, performing blow drying by using cold air, wherein the biofilm solution includes the following components: chitosan, an antioxidant of bamboo leaves and tea polyphenols, and performing fermentation on the meat sausages coated with the biofilm at a temperature of 20-25 DEG C and relative humidity of 70-75% to obtain the air-dried sausages. According to the method, the antioxidant additives are used in the form of the biofilm to prepare the air-dried sausages, so that the occurrence of an oxidation process in the fermentation process can be effectively controlled, and the antioxidant additives can be prevented from affecting on the gelation of the air-dried sausages.

The invention discloses a preparation method and application of konjak gel powder, and belongs to the technical field of food and food dietary fiber additives. The preparation method comprises the following steps: step 1, respectively weighing konjac powder, alkali, water-soluble cellulose, non-water-soluble cellulose, glycerol, ethanol and water; and 2, uniformly stirring and mixing the weighed raw materials, placing at room temperature, heating, curing and forming, dicing, rinsing, soaking and cooking in boiling water, drying, and crushing into powder, thereby obtaining the konjak gel powder. The invention also discloses the application of the prepared konjac gel powder. The acetyl retention degree of the prepared konjak gel powder is 20-60%, the content of glucomannan is larger than or equal to 90%, the residual rate of trimethylamine is smaller than or equal to 0.005%, 5-12 times of water absorption performance is reserved, the konjak gel powder has high porosity, adsorbability to various toxins is remarkably improved, the konjak gel powder has good bowel-relaxing, intestine-moistening and toxin-expelling effects, abdominal distension, abdominal pain and discomfort do not exist after the konjak gel powder is eaten, and the constipation phenomenon is avoided.

The invention discloses a preparation method of a hydrogel eye mask without a base cloth as a carrier. The preparation method comprises the following steps of: selecting raw materials, wherein the raw materials of the eye mask comprise konjac glucomannan, a plant essence composition, a functional mixture, a skin moistening mixture, gelatin, collagen, hyaluronic acid powder, a bonding mixture and alkali; the plant essence composition comprises rose hydrolat, neroli hydrolat, lavender hydrolat and tremella essence; and obtaining solution: sequentially adding the functional mixture, the skin moistening mixture, the collagen, the hyaluronic acid powder, the bonding mixture, the alkali and the water into a mixing device, starting the mixing device for mixing, sequentially adding the gelatin and the plant essence composition after uniform mixing, performing uniform stirring again, finally, adding the konjac glucomannan for stirring, till the raw materials are completely dissolved to form a hydrogel solution. The konjac glucomannan is adopted as a hydrogel carrier, so that the application effect is improved, and the base cloth is prevented from being used as a carrier.

Provided is a cosmetic composition in the form of moldable and stretchable gel, comprising carrageenan and a polysaccharide selected from mannan and glucomannan in an aqueous phase in a weight ratio between 5: 95 and 60: 40. A cosmetic process for caring for skin is also provided, comprising stretching the cosmetic composition according to the present invention into a gel with suitable shape and size and applying said gel to the skin for a period of time.

The invention discloses a prebiotic composition as well as a preparation method and application thereof. The prebiotic composition comprises resistant starch, konjac glucomannan, fructo-oligosaccharide, nectarine powder, oolong tea powder, erythritol and inulin. By eating the prebiotic composition, the abundance of probiotics in intestinal tracts is improved, the abundance of harmful bacteria is reduced, and meanwhile, the content of short-chain fatty acid in the intestinal tracts is increased. By utilizing the synergistic effect of the konjac glucomannan and the resistant starch, water which is 8-20 times of the weight of the konjac glucomannan is added, and the konjac glucomannan and the resistant starch are stirred to uniform to form the stable hydrogel. The effects of enhancing the human body immune function, improving the basic metabolism level and promoting digestion and defecation are achieved through the change of probiotic strains.

The invention discloses a DNA protective agent and a DNA sulfite conversion method, and relates to the technical field of DNA methylation state analysis and detection. The DNA protective agent comprises hydroquinone, dimethyl sulfoxide and a DNA anti-degradation agent, and the DNA anti-degradation agent is glucomannan and / or arabic gum. The DNA protective agent can obviously reduce damage to DNA in the transformation process, avoid DNA degradation and maintain the integrity of the DNA. Besides, the high conversion rate of the non-methylated cytosine can be realized to a great extent, and the melting temperature of the DNA can be reduced to a great extent, so that the high-temperature denaturation time is indirectly shortened, and the problems of breakage and degradation caused by high-temperature damage of the DNA are solved.