39 results about "Ethoxyacetic acid" patented technology

A synthetic reaction to produce [2-(2-aminoethoxy)ethoxy] acetic acid (AEEA) derivatives. This synthetic reaction does not require isolation and purification of intermediates. The AEEA derivatives can be used to synthesize high load polystyrene-polyethylene glycol-like resins having excellent swelling characteristics.

The invention discloses a recycling processing technology for high-salt wastewater during carboxymethyl cellulose production. The processing technology combines extraction and graded crystallization technologies. In the graded crystalization process, through multi-effect (or mechanical recompression) evaporation crystallization, crude salt is recovered from wastewater and condensate water is evaporated, the condensate water reaches the industrial reuse water standard, and refined salt is prepared from crude salt through washing; and then through cooling crystallization, sodium glycollate crystal is separated out, the crystallization mother liquid is used for a next crystallization process, so that closed cycle is realized. In the above graded crystallization process, ethoxyacetic acid is obtained by performing extraction separation on a concentrated liquid, and the viscosity is reduced. The method is simple in operation, low in cost and high in separation recovery rate. The whole processing technology employs closed cycle, has no pollutants, and is easy for industrialization. The technology helps to solve the high-salt wastewater processing problem in the carboxymethyl cellulose production process, also helps to realize the recycling processing purposes of turning harm into good and changing wastes into valuables, and has substantial economic, social and environment benefit.

The invention relates to a synthesis method of 2, 2-ethoxyethanol, belonging to the technical field of medicine and chemical industry. The method comprises the steps of: taking compound of a formula (I) as a raw material, and hydrolytically reacting the raw material with inorganic acid to obtain dichloroacetic acid; reacting the obtained dichloroacetic acid with caustic alcohol in absolute ethyl alcohol in a backflow way, adding hydrochloric acid ethanol solution in a cooling way after the reaction, adjusting PH value, filtering and distilling to obtain 2, 2-ethyl diethoxyacetate; and reacting the 2, 2-ethyl diethoxyacetate obtained in step b with KBH4 and inorganic catalyst in inorganic catalyst in a backflow way to obtain the 2, 2-ethoxyethanol. The synthesis method has the advantages that the raw material is easily obtained, the technical process is simple, the reaction condition is stable, the reaction can be performed without high pressure, and the synthesis method is suitable for the industrial production on a large scale. The solvent ethanol can be recovered and used mechanically, the atom economy is good, the cost is low, the product yield is high, and the product quality is more than 98%.

A method for recycling ethoxyacetic acid from sodium carboxymethylcellulose industrial wastewater comprises the following steps that (1), the pH value of the sodium carboxymethylcellulose industrial wastewater is adjusted to 11.0-12.0, and then the wastewater is subjected to decompression and distillation to obtain a white solid; (2) the white solid obtained in the step (1) is eluted by concentrated hydrochloric acid, the obtained hydrochloric acid solution is extracted for 3 times by an organic solvent, and organic phases are separated out for standby application; (3), the organic phases obtained in the step (2) are subjected to decompression and distillation to obtain ethoxyacetic acid products. According to the method for recycling the ethoxyacetic acid from the sodium carboxymethylcellulose industrial wastewater, operation is convenient, the cost is low, and recycling and reusing of resources are achieved.

The invention provides a deodorization and degradation treatment agent composition for treating municipal waste landfills and refuse power plant leachate, which is made of the following raw materials in parts by weight: 6-9 parts of ammonium persulfate, persulfuric acid 4-7 parts of potassium, 11-16 parts of potassium carbonate, 2-4 parts of sodium silicate, 8-10 parts of potassium oxalate, 3-5 parts of polyethylene glycol ether, 2-4 parts of sodium propoxide, ethoxylate Potassium glycolate 6-9 parts, decyldimethylamine 3-6 parts, sodium methacrylate 1-3 parts, laurylamine 8-11 parts, sulfosuccinic acid 5-8 parts, hydroxyethylethylenediamine 2 to 4 parts, 0.1 to 0.3 parts of lipase. During the treatment process, it only eliminates the odor of the landfill leachate within a few seconds to a few minutes, and reduces the ammonia nitrogen content in the landfill leachate by more than 50% within ten minutes, saving time and money for the next biochemical treatment of waste, reaching Non-toxic and tasteless, rapid deodorization and degradation of landfill leachate purposes. The invention also provides a preparation method of the deodorizing degradation treatment agent composition.

The invention discloses a method for synthesizing 1,4-dioxane-2-ketone by ethylene glycol. The method comprises the following steps of: 1, synthesis of ethylene glycol monosodium: mixing a dehydrating agent, ethylene glycol and sodium hydroxide for reaction, cooling down the mixed solution to the room temperature after reaction, standing the mixed solution for demixing to obtain upper-layer liquid, and directly using the upper-layer liquid in the next reaction, wherein the ethylene glycol mixed in the lower-layer ethylene glycol monosodium is unnecessarily separated; 2, synthesis of beta-hydroxyethoxy sodium acetate: mixing ethylene glycol, sodium monochloroacetate and ethylene glycol monosodium for reaction, adding sulfolane to the mixed solution after reaction, recovering ethylene glycol by vacuum distillation, cooling down the mixed solution, then adding acetone to the mixed solution, and obtaining a coarse product of beta-hydroxyethoxy sodium acetate; and 3, synthesis of 1,4-dioxane-2-ketone by ethylene glycol: adding beta-hydroxyethoxy sodium acetate to an oxygen heterocycle containing solvent, slowly adding concentrated sulfuric acid to the mixed solution dropwise when the mixed solution is stirred, and obtaining the finished product of 1,4-dioxane-2-ketone by ethylene glycol. The method takes ethylene glycol as a synthetic raw material, the products are easily separated, and the selectivity is high; and the solvents used in the reaction can be recovered in high efficiency for reutilization, so that the method is environment friendly.

The invention relates to a preparation method of a simvastatin ammonium salt. A substrate monacolin J acid, 2,2-dimethylbutyric acid-2-sulfhydrylethoxyacetate and ammonia water react under the pH value of 8.5-10 under the action of recombinant acyltransferase to generate the simvastatin ammonium salt, wherein the mass ratio of the monacolin J acid to the 2,2-dimethylbutyric acid-2-sulfhydrylethoxyacetate is 1:(0.6-1). The 2,2-dimethylbutyric acid-2-sulfhydrylethoxyacetate, which has the advantages of low addition amount and cheap synthesis raw material and is easy to synthesize, is used as an acyl donor for synthesizing the simvastatin side chain, so the method obviously lowers the production cost and has important use value.

The invention provides a method for efficiently preparing a key rivaroxaban intermediate, namely, 4-phenylmorpholine-3-ketone, by the one-step process through aniline and halogen ethyl acetate, aiming at solving the technical problems that the conventional synthesis method of 4-phenylmorpholine-3-ketone has a plurality of steps, rigorous requirements on reaction condition, low yield, and complex and complicated product purification. The preparation method has the advantages that the reaction conditions are mild, the yield is high, and industrial production can be carried out. The reaction formula is shown as the description.

The invention relates to a synthesis method of 4-tert-butyl-5-ethyl-6-oxo-1, 4-oxyaza-4, 5-dicarboxylic acid, and solves the technical problems of difficult synthesis operation and expensive raw materials in existing methods. The method includes: reacting 2-benzylaminoethanol as the starting raw material with t-butyloxycarboryl to protect amino to obtain tert-butylbenzyl(2-hydroxyethyl)carbamate, reacting the product with sodium hydride in ice bath, then reacting the reaction product with ethyl bromoacetate to obtain ethyl 2-(2-(benzyl)t-butyloxycarboryl)amine)ethoxy)acetic acid, then removing Boc with a hydrochloric acid ethyl acetate solution to obtain ethyl 2-(2-(benzylamine)ethoxy)acetic acid hydrochloride, and then in the presence of alkali, reacting the ethyl 2-(2-(benzylamine)ethoxy)acetic acid hydrochloride with ethyl bromoacetate to obtain ethyl 2-(benzyl(2-(2-ethoxy-2-oxoethoxy)ethyl)amino)acetic acid, using palladium hydroxide as the catalyst, in the presence of di-tert-butyl carbonate, removing Boc from benzyl with hydrogen to obtain ethyl 2-((t-butyloxycarboryl)(2-(2-ethoxy-2-oxoethoxy)ethyl)amino)acetic acid, and finally under a potassium tert-butoxide alkaline condition and with toluene as the solvent, conducting backflow and ring closing so as to obtain a final compound.