45 results about "Drug adsorption" patented technology

Compositions which deliver adsorbents, alone or in combination with active drug “degrading molecules,” in a site-specific manner to the intestine, and which eliminate or at least lower the concentration of residual unwanted material within the intestine, are disclosed. Methods of treatment using the compositions are also disclosed. The material to be eliminated can include residual active antibiotics, metabolites, bacterial or other toxins, and drugs which cause side effects in the gastrointestinal tract. The adsorbents can be formulated in capsules, tablets or any acceptable pharmaceutical composition, and are ideally designed to specifically release the adsorbents in a programmed manner at a specific site of the intestinal tract. The programmed delivery prevents adsorbents from interfering with the normal absorption process of a given molecule after oral absorption, until it reaches the lower part of the small intestine. The compositions can be used to adsorb, and therefore remove, any residual drug, metabolite thereof, or bacterial toxin after oral or parenteral administration which would otherwise cause adverse effects in the lower intestine and / or colon.

A solid drug solution perforator containing drug particles (402) and / or drug-adsorbed or loaded particles with an associated drug reservoir (SSPP system) (40Q) are provided for delivering therapeutic,prophylactic and / or cosmetic compounds, diagnostics, and for nutrient delivery and drug targeting. For drug delivery, the SSPP system includes an active drug ingredient (402) in particulate form or drug adsorbed on the particle surface in a matrix material (411) that dissolves upon contact with a patient's body (11). In a preferred method of transdermal drug delivery, an SSPP system containing adrug-adsorbed microparticle (402) penetrates into the epidermis (15) or dermis (17), and the drug (402) is released from the (dissolving) SSPP system perforator (400) and desorbed from the particles.An additional drug is optionally delivered from a patch reservoir (601) through skin pores created by insertion of the perforator. Formulation and fabrication procedures for the SSPP and associated reservoir are also provided. An SSPP system can be fabricated with variety of shapes and dimensions.

The invention relates to dapoxetine tablets and a preparation method thereof. The dapoxetine tablets comprise the following components in percentage by weight: 10 to 50 percent of dapoxetine, 30 to 80 percent of a filling agent, 3 to 20 percent of a disintegrant, 0.5 to 1 percent of a lubricant and 0.2 to 2.5 percent of a flavoring agent. The preparation method comprises the following steps: micronizing the dapoxetine and the filling agent and controlling the particle size to be 0.5-20 [mu]m; preparing the fine powder obtained in the previous step and a part of the disintegrant into a soft material by ethanol water and pelletizing by a 24-mesh sieve; drying the obtained fine particles at the temperature of 50 to 70 DEG C and straightening by a 20-mesh sieve; sequentially adding the rest disintegrant, the flavoring agent and the lubricant into the dried particles, carrying out blending for two times, and until intermediates are qualified by detection, and carrying out tabletting, so that the dapoxetine tablets are obtained, wherein blending is carried out for one time before the lubricant is added and then is carried out again after the lubricant is added. The dapoxetine tablets are coated or uncoated conventional tablets, chewable tablets and orally disintegrating tablets, are used for treating male prospermia, high in drug adsorption speed and bioavailability, and convenient to take and have small side effects.

A fluid dynamic valve passively allows fluid flow out of a moving stream in one flow direction and not in the reverse. This allows the collection of fluid from a single direction of an AC fluid flow. The siphoned portion of the flow has a flow rate proportional to the mainstream flow. This device can collect exhaled breath or selective entrenchment during inhale. In one orientation, it can meter aerosolized particles into an inhale breath stream for pulmonary delivery, without complicated breath timing or drug loss due to drug adsorption to the back of the throat. Alternatively, a user can breathe through the device and a proportional amount, relative to the volumetric flow rate, of each exhale can flow into an auxiliary chamber for analysis. In addition, the device has a low respiratory burden and is comfortable to use.

The invention discloses a preparation method for a botanical pesticide for specially killing cabbage caterpillars during organic vegetable planting. The preparation method comprises the following steps: 1), preparing raw materials, wherein the raw materials comprise the following components in parts by weight: 10-15 parts of radix sophorae flavescentis, 7-10 parts of melia toosendan, 12-19 parts of melia toosendan bark, 10-15 parts of tripterygium glycosides, 18-24 parts of raw kusnezoff monkshood roots, 4-6 parts of radix euphorbiae lantu, 6-8 parts of pericarpium citri reticulatae and 13 parts of tobacco; 2), adding 3 to 4 times of water by weight in the raw materials, decocting in a sealing manner at the temperature of 90-100 DEG C for 100 to 120 minutes, filtering, and concentrating the filtrate to be 1 / 3-1 / 4 of the original used water amount to obtain the botanical pesticide for specially killing pierisrapae linne. The botanical pesticide can targetedly and specially kill cabbage caterpillars by scientific compatibility of the traditional Chinese medicine components, and is high in permeability, conducive to plant uptake, low in cost, free of three-evil, residue, pollution and drug resistance, high in drug adsorption, and long in drug effect duration.