45 results about "Drug adsorption" patented technology

A solid drug solution perforator containing drug particles (402) and / or drug-adsorbed or loaded particles with an associated drug reservoir (SSPP system) (40Q) are provided for delivering therapeutic,prophylactic and / or cosmetic compounds, diagnostics, and for nutrient delivery and drug targeting. For drug delivery, the SSPP system includes an active drug ingredient (402) in particulate form or drug adsorbed on the particle surface in a matrix material (411) that dissolves upon contact with a patient's body (11). In a preferred method of transdermal drug delivery, an SSPP system containing adrug-adsorbed microparticle (402) penetrates into the epidermis (15) or dermis (17), and the drug (402) is released from the (dissolving) SSPP system perforator (400) and desorbed from the particles.An additional drug is optionally delivered from a patch reservoir (601) through skin pores created by insertion of the perforator. Formulation and fabrication procedures for the SSPP and associated reservoir are also provided. An SSPP system can be fabricated with variety of shapes and dimensions.

The invention relates to dapoxetine tablets and a preparation method thereof. The dapoxetine tablets comprise the following components in percentage by weight: 10 to 50 percent of dapoxetine, 30 to 80 percent of a filling agent, 3 to 20 percent of a disintegrant, 0.5 to 1 percent of a lubricant and 0.2 to 2.5 percent of a flavoring agent. The preparation method comprises the following steps: micronizing the dapoxetine and the filling agent and controlling the particle size to be 0.5-20 [mu]m; preparing the fine powder obtained in the previous step and a part of the disintegrant into a soft material by ethanol water and pelletizing by a 24-mesh sieve; drying the obtained fine particles at the temperature of 50 to 70 DEG C and straightening by a 20-mesh sieve; sequentially adding the rest disintegrant, the flavoring agent and the lubricant into the dried particles, carrying out blending for two times, and until intermediates are qualified by detection, and carrying out tabletting, so that the dapoxetine tablets are obtained, wherein blending is carried out for one time before the lubricant is added and then is carried out again after the lubricant is added. The dapoxetine tablets are coated or uncoated conventional tablets, chewable tablets and orally disintegrating tablets, are used for treating male prospermia, high in drug adsorption speed and bioavailability, and convenient to take and have small side effects.