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Silicon nitride infusion filter membrane, preparation method thereof, filter and infusion device

A silicon nitride filter membrane, silicon nitride film technology, applied in chemical instruments and methods, filter accessories, membrane technology, etc., can solve the problems of complex routes, pressure loss, long filter paths, etc.

Inactive Publication Date: 2018-12-28
常州费曼生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The polymer nanofiltration membrane is used for the filtration of drugs, and there are mainly the following deficiencies at present: the drug filtration path is long and complicated, which will increase the adsorption of drugs on the filter membrane; the swelling phenomenon of the polymer filter membrane in the liquid medicine , it is easy to cause changes in the filtration channel, resulting in a change in filtration performance; long filtration path, resulting in a large pressure loss and affecting the filtration flow rate
[0009] Therefore, there is no pure inorganic material membrane technology that can reach 0.2 micron in the precision filter mentioned in the above patent or product.

Method used

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  • Silicon nitride infusion filter membrane, preparation method thereof, filter and infusion device
  • Silicon nitride infusion filter membrane, preparation method thereof, filter and infusion device
  • Silicon nitride infusion filter membrane, preparation method thereof, filter and infusion device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] like Figure 1~3 As shown, a silicon nitride material infusion filter membrane, it includes a body, the body has:

[0050] Monocrystalline silicon grid support body 86;

[0051] A silicon nitride filter membrane 87 arranged on the top surface of the single crystal silicon grid support body 86, the silicon nitride filter membrane 87 has a plurality of through filter holes, and the diameter of the filter holes is 0.2 micron to 1 micron , the depth of the filter holes is 0.1 micron to 0.5 micron, and the density of the filter holes on the surface of the silicon nitride filter membrane 87 can be 1 million to 600 million per square centimeter of surface area.

[0052]The grid side length or grid aperture of the single crystal silicon grid support body 86 is 0.05 mm to 2 mm; the total thickness of the body is 100 microns to 450 microns.

[0053] According to filtering needs, the pore size of silicon nitride filter membrane 87 can be set to 0.2 micron, will be blocked by sil...

Embodiment 2

[0069] like Figure 1~3 As shown, a filter that includes:

[0070] The silicon nitride material transfusion filter membrane 83 in embodiment one;

[0071] Housing 85, the silicon nitride material infusion filter membrane 83 is arranged in the housing 85, and the housing 85 is divided into a liquid inlet chamber and a liquid outlet chamber by the silicon nitride material infusion filter membrane 83; specifically , the surroundings of the precision infusion filter membrane 83 made of monocrystalline silicon are bonded and sealed with the casing 85, and the liquid inlet chamber and the liquid outlet chamber are completely isolated by the precision infusion filter membrane 83 made of monocrystalline silicon;

[0072] An infusion inlet 81, the infusion inlet 81 is connected to the housing 85, and the infusion inlet 81 communicates with the liquid inlet chamber;

[0073] A filtrate outlet 84, the filtrate outlet 84 is connected to the housing 85, and the filtrate outlet 81 communi...

Embodiment 3

[0076] like Figure 4 Shown, a kind of infusion set, it comprises:

[0077] The filter in embodiment two;

[0078] Conduit 5, one end of said conduit 5 communicates with the filtrate outlet 84 of filter 8;

[0079] A burette 4, one end of the burette 4 communicates with the other end of the conduit 5;

[0080] A puncture assembly, the puncture assembly is connected on the burette 4;

[0081] A speed regulator 7, said speed regulator 7 is arranged on the conduit 5.

[0082] like Figure 4 As shown, the infusion set also includes a three-way piece, the inlet of the three-way piece communicates with the filtrate outlet 84 of the filter 8, and one branch of the three-way piece communicates with one end of the conduit 5, and the three-way piece Another part of the part is the filling port 6.

[0083] like Figure 4 As shown, the burette 4 is provided with a drip pot 3, and the puncture assembly includes a piercer 2, and the piercer 2 communicates with the drip pot 3; the pie...

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Abstract

The invention discloses a silicon nitride infusion filter membrane, a preparation method thereof, a filter and an infusion device. The silicon nitride infusion filter membrane comprises a body. The body is provided with a monocrystalline silicon grid support body and a silicon nitride filter membrane arranged on the top surface of the monocrystalline silicon grid support body. The silicon nitridefilter membrane is provided with a plurality of penetrating filtering holes with the diameter of 0.2-1 micron and the depth of 0.1-0.5 micron. The silicon nitride filter membrane is integrally connected with the monocrystalline silicon grid support body, has good bonding strength and sealing performance, ensures the sound condition under the stress state, and has high strength and good elasticity.The filter membrane thickness is controlled below 1 micron. The filter membrane further has the advantages of good biocompatibility, short filtering path, low filtration pressure difference, low filter membrane swelling and less drug adsorption, and can better meet the nano ultrafiltration infusion requirements of different types of drugs due to the fact that the filter membrane surface modification is more convenient.

Description

technical field [0001] The invention relates to a silicon nitride transfusion filter membrane, a preparation method thereof, a filter and a transfusion set. Background technique [0002] At present, intravenous infusion is one of the most common methods of drug delivery. The active ingredients in the drug solution are transported into the human blood circulation system to treat the diseased area, which has become a common drug treatment method. The common problem faced by this kind of drug delivery is that due to the limitations of the current drug production technology and environmental conditions such as transportation and storage, the drug solution often still contains microparticles of different diameters, and the infusion process enters the blood system together with the effective drug components, and It will have varying degrees of impact on human health, and may cause serious harm to human tissues or organs, and in severe cases may endanger human life. [0003] At pr...

Claims

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Application Information

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IPC IPC(8): B01D67/00B01D69/10B01D71/02A61M5/14A61M5/165
CPCA61M5/14A61M5/165A61M2005/1657B01D67/0039B01D69/10B01D69/105B01D71/02
Inventor 蒋开
Owner 常州费曼生物科技有限公司
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