1724results about How to "Increase intake" patented technology

A novel dosage form. The dosage form is presented in particulate form and before oral ingestion the particulate material is subjected to an aqueous medium, whereby it is converted to a semi-solid form by swelling or gelling of one or more of the components, especially of a gellan gum, of the particulate matter. The invention also relates to a vehicle for oral administration of one or more active substances, the vehicle comprising a gellan gum arranged in a configuration allowing optimal water diffusion so that upon addition of a predetermined amount of an aqueous medium, without the necessity of applying shear forces or other mixing forces, within a time period of 5 minutes or less swells and/or gels and the texture of the swelled vehicle being similar to that of a soft pudding and having a viscosity of at least about 10,000 cps as measured by a Brookfield Viscometer with a #4 LV spindle at 6 rpm and at 20-25° C. In one embodiment of the invention, the particulate matter can be moulded into a desired shape or pressed onto a dispensing unit such as a spoon.

A valve overlap period is increased as a desired torque of an engine increases by advancing an opening timing of an intake valve at a rate greater than that of retarding a closing timing of an exhaust valve in a low engine-torque area in which the desired torque of the internal combustion engine is relatively low (step S16). The valve overlap period is increased as the desired torque of the engine increases by retarding the closing timing of the exhaust valve at a rate greater than that of advancing the opening timing of the intake valve in a high engine-torque area in which the desired torque of the internal combustion engine is relatively high (step S17). Accordingly, the drivability can be improved by obtaining the proper torque and the smooth torque curve in the wide driving area.

The invention discloses an application of nanometer structure lipid carrier administration system in the antineoplastic drug to reverse the multiple-drug tolerance of tumour cell, which comprises the following parts: solid lipid material, liquid lipid material and antineoplastic drug, wherein the rate of the liquid lipid (such as oleic acid) is 0-30wt%; the solid lipid is selected from monoglyceride; the liquid lipid is oleic acid; the antineoplastic drug is Paclitaxel or adriablastina. The invention has highly effective cell uptaking and cytolymph condensing function with packing molecular target in the antineoplastic drug of cell, which avoids P-glucoprotein in the drug tolerant cytolymph from identifying the antineoplastic drug to reduce exclusion.

Feedback systems and methods enhance obstructive and other obesity treatments by presenting feedback regarding patients' actual eating and/or exercise habits. An ingestion restricting implant body can be deployed along the gastrointestinal tract. In some embodiments, ingestion alters the implant body, which, in turn, generates signals. The generated signals can be used to inhibit unhealthy ingestion by the patient. In other embodiments, the implant body can be altered by signals so as to selectable change the restriction imposed on the gastrointestinal tract, optionally in response to ingestion events, an eating schedule, or the like. The implant body may comprise a gastric band or an intragastric balloon. Sensor signals may be processed to identify ingestion and/or characterize ingestion of a solid or a liquid, and the results may be displayed on a screen for a patient or coach to view.

A battery operated pill crusher is provided having a motorized, rotating plunger in a portable configuration.

A water insoluble, water swellable absorbent composition exhibiting a free swell absorbency of at least 15 g/g and an Absorbency Change of greater than or equal to 15% upon saturation. The absorbent composition includes both permanent crosslinking points and transitional crosslinking points. The absorbent composition has a high free swell capacity as well as a high absorbency under load.

The invention relates to a preparation method for a zinc-iron-selenium-rich biological fertilizer and a usage, which belongs to the technical field of crop production. Water is added into pig manure, silkworm excrement, human excrement and colza cakes for a fermentation to get mother liquor of the biological fertilizer; zinc sulfate, green copperas, sodium selenite are added into the mother liquor for reactions to get zinc-iron-selenium-rich biological foliar fertilizer for the rice. The fertilizer is separately sprayed in the booting stage and the full heading stage of the rice, with an amount of 1000ml per mu. The function rice, with zinc content 19.4 to 28.7mg/kg, iron content 7.0 to 20.2mg/kg, and selenium content 0.08 to 0.15 mg/kg, measures up to the limit standards of zinc, iron, and selenium in the national food standards. Organic selenium accounts for more than 99% of the total selenium in the zinc-iron-selenium-rich function nutritive rice. The preparation method for the zinc-iron-selenium-rich biological fertilizer proves effective, economical, safe and non-polluted through twice foliage sprays with zinc-iron-selenium fertilizer for the rice as an experiment.

The invention relates to dosage forms that provide prolonged therapy. In particular, the invention relates to dosage forms including various pluralities of drug-containing resin particles. The invention also relates to methods of making these dosage forms and methods of treating using these dosage forms.

The invention relates to the field of production of ultrawhite rolled glass, in particular to a preparation method of solar ultrawhite ultrathin glass and a product thereof. The preparation method of the solar ultrawhite ultrathin glass comprises the following steps of: selecting and preparing raw materials; conveying the raw materials; melting; forming glass; annealing; detecting; and cutting and packaging. In the preparation method, iron content is controlled by taking different measures in the steps of selecting and conveying the raw materials, so that iron sulfide in the final solar glass is greatly reduced and the whiteness of the glass is improved; in the melting process, bubbles in the melted glass liquid is reduced by exhausting air and debubbling, controlling temperature and adding a glass clarifying agent, so that absorption rate is reduced and light transmittance is improved; and the annealing step of the glass finished product is a key link of the production process and plays an important role in the quality of the ultrathin glass product, so the defects that the ultrathin glass is easy to harden and easy to break during production and has high fragility are overcome by controlling rolling velocity, temperature and annealing rate in the process of glass forming and glass annealing.

The invention belongs to the technical fields of immunology and tumor therapy, and relates to a preparation method and a use of a TCR gene modified CD8+T memory stem cell. The method comprises the following steps: co-incubating a tumor antigen and an immature dendritic cell to obtain a specific tumor antigen-supported mature dendritic cell, co-culturing the specific tumor antigen-supported maturedendritic cell and a CD8+ naive T cell, and adding a stem cell differentiation inhibitor to promote the generation of a CD8+ stem cell-like memory T lymphocyte; separating the CD8+ stem cell-like memory T lymphocyte; and cloning a T cell receptor gene (TCR) for specifically identifying a specific antigenic epitope, and carrying out lentivirus packaging or retroviral vector cotransfection on an autologous CD8+ Tscm cell to in-vitro prepare a CD8+ TCR-Tscm cell specific for different tumor specific antigens. The CD8+ TCR-Tscm cell prepared by the method has the advantages of overcoming of the tumor heterogeneity, high specificity, few adverse reactions, and highly-efficient and lasting tumor preventing and treating effects.

The invention relates to a multi-function nano prodrug system based on a dendrimer, which belongs to the technical field of biomedicines and nano medical science. The nano system comprises four function parts: an outermost layer RGD (arginyl-glycocoll-aspartate) cyclic peptide as an active targeting head group (1), a polyethylene glycol (PEG) hydrophilic chain segment (2) connected with the targeting head group and the dendrimer, an anti-tumour drug (3) connected with the dendrimer by an acid sensitive chemical bond and a dendrimer kernel (4). The general formula of the nano system is RGD-PEG-Dendrimer-DOX (doxorubicine), wherein the macromolecule attribute of a dendrimer vector makes a vector system passively target to tumor tissues through an EPR (Enhanced Permeability and retention) effect; the RGD cyclic peptide makes the vector system actively target to the tumor tissues through the interaction of a ligand and a receptor and promotes the endocytosis of the tumor tissues; the acid sensitive chemical bond ensures that a drug-carrying system is stable in systemic circulation and releases active drugs after arriving tumor positions and entering an acid organelle to perform the function of cytotoxicity.

The invention discloses phospholipid derivatives for branching polyethylene glycol, and a lipid membrane structural body composed of the same. The general formula of the phospholipid derivatives is as shown in the specification, wherein X1 and X2 are hydroxyl with 1-20 carbon atoms respectively and independently; n1 and n2 are integers ranging from 1 to 1000 respectively and independently, n3 is an integer ranging from 0 to 1000, and n1+n2+n3 is not less than 2 and not greater than 2000; Y is a branching centre with 1-20 carbon atoms, and connected with L1, L2 and L3 by a covalent bond; L1, L2 and L3 are linking groups for Y and polyethylene glycol units; q is 0 or 1; when n3=0, q is 0 and Y is not the polyamino acid residue of 2-10 amino acid residues; L4 is a linking group; M is hydrogen atom or cation; R is the residue of hydrophobic lipids. The lipid membrane structural body composed of the phospholipid derivatives for branching polyethylene glycol is used for wrapping a medicine and capable of effectively prolonging the cycle time of the medicine in a body.

The invention discloses a health care product with the function of reducing blood sugar. The health care product comprises L-arabinose, chromium-enriched yeast and any one or more of taurine, Chinese wolfberry extract, L-carnitine tartrate and bitter melon extract. The health care product has the functions of reducing the blood sugar and controlling blood fat simultaneously, has good taste, and is particularly suitable for patients with diabetes.

The invention provides a special dietary food suitable for old people with sarcopenia to eat. The special dietary food is characterized by being prepared from the following components in parts by weight: 3-53.5 parts of proteins, 1-2 parts of calcium beta-hydroxy-beta-methyl butyrate, 2-5 parts of dietary fibers, 0.8-2 parts of fatty acid, 0.2-1.3 parts of compound vitamins and 1.5-2 parts of composite mineral substances. The food has the advantages of simple and convenient production process, safety in eating, good mouth feel and no side effect, can be used for delaying the sarcopenia of the old people, has prevention and improvement effects and is suitable for people to use for a long period.

The present invention discloses a compound of paligorskite health-care sand for carrier pigeon. Its composition includes the following ingredients: (by weight portion) 18-22 portions of paligorskite, 34-37 portions of river sand, 12-13 portions of oyster shell powder, 9-11 portions of bone powder, 4-6 portions of edible salt, 10-11 portions of Chinese medicinal materials, 2-3 portions of trace element, 2-3 portions of amino acid and 2-3 portions of vitamin. Said invention also provides its production method.

The invention discloses a nano aluminum-encapsulating carrier and an application of the nano aluminum-encapsulating carrier in constructing a vaccine adjuvant transfer system. The nano aluminum is nanoparticles of aluminum phosphate, aluminum sulfate and aluminum hydroxide or a mixture of aluminum phosphate, aluminum sulfate and aluminum hydroxide, wherein the grain size is below 1 mu m; the carrier is a lipidosome, a lipoid, an emulsion, a nano-capsule or a micro-capsule. Construction of the vaccine adjuvant transfer system is the main purpose of the nano aluminum-encapsulating carrier. The application of the nano aluminum-encapsulating carrier in constructing the vaccine adjuvant transfer system comprises the following step: encapsulating vaccine components in the nano aluminum-encapsulating carrier; or adsorbing the vaccine components on the surface of the carrier; or purely mixing with the carrier to exert the vaccine adjuvant and the transfer function. The nano aluminum-encapsulating carrier disclosed by the invention has the advantages that the nano aluminum-encapsulating carrier is wide in application range, so that the nano aluminum-encapsulating carrier is suitable for antigens with different pathogens; the nano aluminum-encapsulating carrier is high in stability and can encapsulate antigens so as to enhance in vivo and in vitro stability; the nano aluminum-encapsulating carrier is high in safety, and the use materials have good biocompatibility; the nano aluminum-encapsulating carrier is many in inoculation and wide in way, and the carrier can be inoculated through track mucosa or subcutaneous, intracutaneous and intramuscular injection; the carrier is strong in immunosuppression induction potency.