53 results about "Cell ageing" patented technology

This invention is directed to a skin care composition comprising a laminriacea (brown seaweed) extract and the use of said composition in the treatment of skin aging signs Specifically, it was discovered that a crude extract of the laminariacea Saccharina Longicruris has a strong potential for anti-senescence and anti-cellular aging effect and is efficient to restore the contraction of the collagen network of aged cell lattices to the level of contraction of young cells.

The invention discloses a method for preparing a population of?human pluripotent stem cells and the application thereof. The preparation of stem cells is characterized by comprising the following steps: CD151<+>, CD31<->, Sox<2+> pluripotent stem cells are separated and collected from human umbilical cord and or placenta tissues; the cells adhere to grow in a culture vessel under a predetermined condition and expand through passage 20 or above to be still stable in gene expression. The population of cells of this invention do not form teratoma after injection into animals. The human pluripotent stem cells highly express CD151, OCT4 and Sox-2 as specific markers of embryonic stem cells, as well as specific markers of epidermic cells, endothelial cells, thrombocytes, dendritic cells, while lack expression of CD31, CD34, CD45 and HLA-II. The pluripotent stem cells are also characterized as being able to adhere to tissue culture plastic and having the potential to differentiate into three germ layers: endoderm, mesoderm and ectoderm. These pluripotent stem cells are able to be used as carrier cells of gene therapy and for the treatment of diseases caused by cell damage or cell aging. The present invention provides a method of isolating, purifying and culturally expanding of a population of human pluripotent stem cell for preparing the high purity injection preparation. The preparation of stem cells has a good therapeutic effect on the treatment of diseases caused by cell damage or cell aging in animal and human clinical trials. The preparation also has no toxic side effect and no immune rejection.

The invention discloses a Pycnogenol / rhEGF composition skin care cosmetic and a preparation method thereof. The Pycnogenol / rhEGF composition skin care cosmetic is prepared from six-phase materials, wherein, two main components comprise, by weight, 1.4 to 1.6% of Pycnogenol and 0.01 to 0.1% of rhEGF. According to the invention, a high efficiency antioxidation effect of Pycnogenol is utilized to remove free radicals generated by metabolism of a living organism or by physical radiation and chemical substances, to eliminate damage of free radicals to cell membranes and to protect the quantity andproliferation capability of EGFR acceptor protein on the cell membranes; exogenous rhEGF is supplemented so as to maintain the normal physiological level of aging cells EGF and enhance anti-interference ability of skin, thereby effectively repressing cell aging so as to prevent and delay aging of skin.

The invention discloses health care drinking water, and particularly relates to nano platinum drinking water. The nano platinum drinking water is prepared from nano platinum with grain size of less than or equal to 3nm and common drinking water, and the nano platinum content is between 0.4 and 1.6ppm. The nano platinum drinking water contains platinum(Pt) which is called king of noble metal, so that the nano platinum drinking water has multiple efficacies of improving disease resistant capability, resisting oxidation, inhibiting bacteria, promoting blood circulation, enforcing metabolism, resisting cell ageing, preventing cancer and resisting cancer. Moreover, the invention also relates to a method for preparing the nano platinum drinking water.

The methods in this disclosure allow for the identification, selection, and arrangement of cells, blocks, and modules in large scale battery systems, such as electric vehicle battery systems. An example embodiment of the present invention allows for the identification of the cells, blocks, and modules with a unique identifier or associated parameter (e.g., internal resistance contributions or capacity). Additionally, to form a block, cells may be selected from a group of capacity-range sorting bins. Based on a parameter of the cell, a pseudo-number generator may be also be used to select cells from an available inventory of cells as maintained in a cell database based. Cells may also be placed in a block for uniform effective cell impedance and even cell aging while minimizing overall block capacity degradation caused by cycling. Block capacities may also be computed based on a known average temperature gradient during operation.

The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE− / −) mice along with the endothelial cell age-delaying effects of Mito-Esc.

The invention discloses a method for producing oyster mushroom strains from birch chopsticks. The method comprises four steps of: performing pretreatment on the chopsticks, preparing a culture medium for the chopsticks, performing inoculation culture and transferring the strains. According to the method disclosed by the invention, by carrying out pretreatment on the birch chopsticks, on the one hand, harmful substances in the birch chopsticks can be fully decomposed, and on the other hand, convenience is brought to the insertion of the birch chopsticks into a mycelium mass during the inoculation. When a culture medium for the birch chopsticks is prepared, as birch contains a large number of nutrient components required for growth of oyster mushrooms, only sucrose, a compound fertilizer, wheat bran and corn flour need to be further added, therefore the components in a nutrient solution are greatly simplified and the preparation process is also trouble-saving and effort-saving. When the inoculation is performed, only the chopsticks need to be directly inserted into the mycelium mass for completion, the operation process is convenient, fast, effort-saving and labor-saving and the pollution rate is very low. Mycelia are fully grown all over the whole chopstick strains after culture, the cell ages after the inoculation are short and consistent, the strains are fast in growth speed, the mycelia are robust, and the strains are high in purity and strong in resistance to other fungi. The method disclosed by the invention further has the more prominent advantages of low production cost and very significant economic benefits.

The invention discloses markers for identifying or assisting in identifying vascular cells and / or vascular cell aging degrees and applications of the markers. The invention firstly discloses the applications of IL13RA2, WIF1, PTGS1, POSTN, DES, ACTC1, SORBS2 and PEBP4 in preparation of products that identify or assist in identifying the vascular cells. The invention further discloses the application of FOXO3 in preparation of products for identifying or assisting in identifying the aging degrees of the different vascular cells. The markers provided by the invention play an important role in the screening and identification of the vascular cells, can evaluate vascular aging related diseases such as atherosclerosis, and can detect human vascular function and evaluate the degrees of human vascular aging, thereby providing important molecular indications for the research and intervention of the vascular aging related diseases, especially for the evaluation of human cardiovascular functionand disease diagnosis; and the markers have important application value.

The invention discloses a Pycnogenol / rhEGF composition skin care cosmetic and a preparation method thereof. The Pycnogenol / rhEGF composition skin care cosmetic is prepared from six-phase materials, wherein, two main components comprise, by weight, 1.4 to 1.6% of Pycnogenol and 0.01 to 0.1% of rhEGF. According to the invention, a high efficiency antioxidation effect of Pycnogenol is utilized to remove free radicals generated by metabolism of a living organism or by physical radiation and chemical substances, to eliminate damage of free radicals to cell membranes and to protect the quantity andproliferation capability of EGFR acceptor protein on the cell membranes; exogenous rhEGF is supplemented so as to maintain the normal physiological level of aging cells EGF and enhance anti-interference ability of skin, thereby effectively repressing cell aging so as to prevent and delay aging of skin.

The invention discloses blackberry wine capable of delaying cell ageing and a production method of the blackberry wine. The method comprises the steps of carrying out pre-fermentation, carrying out post-fermentation, stopping fermentation, carrying out enzymolysis, carrying out cold treatment and sterilizing. According to the method disclosed by the invention, fresh fructus lycii and folium ginkgoare added into blackberry raw materials according to a certain ratio; the fermentation is carried out so that the content of fructus lycii polysaccharide and flavone in the blackberry wine is increased; meanwhile, the quantity of saccharomycetes is increased in the post-fermentation; the saccharomycetes is self-dissolved in the wine through the enzymolysis and ultrasonic treatment to release a lot of functional substances including yeast polysaccharide, polypeptide, amino acid, nucleotide and the like, so that the health-care function of the blackberry wine is greatly increased; especially, the cell ageing can be delayed. According to the technology disclosed by the invention, high-quality blackberry fruit wine, which has excellent color, flavor and taste and integrates nutrients and health care as a whole, can be obtained.

The invention provides a cosmetic. The cosmetic is mainly prepared from an epidermal stem cell extract and aloe micromolecular bioactive peptide. The provided human epidermal stem cell extract contains various kinds of life active matter, can revitalize skin cells, activate the self-healing function of human body, supplement and condition aged cells, activate cell functions, increase the number ofcells, improve the cell viability, improve the cell quality, improve the material transportation function of cytomembrane and material interchange capability, recover the normal physiological function of cells, and promote corium layer cells to secrete and synthesize functional molecules such as collagenous fiber, polysaccharide and glycoprotein. The provided aloe micromolecular polypeptide can obviously improve the recovery function of the human epidermal stem cell extract on damaged skin, and the function of delaying cell ageing.