The invention belongs to the field of medicaments and provides an application of natural
plant lobedfruit schizocapsarhizome and total
saponin extract of the lobedfruit schizocapsarhizome, wherein the natural
plant extract is total saponins of the lobedfruit schizocapsarhizome (the Latin name is
Schizocapsa plantaginea Hance). The invention provides an extract technology of the total
saponin extract of the lobedfruit schizocapsarhizome and the application of the total
saponin extract of the lobedfruit schizocapsarhizome in treatment of
liver cancer and
nasopharyngeal carcinoma. The extract has strong antineoplastic activity and certain targeting property. Serum
pharmacology tests prove that the extract still has strong pharmaceutical activity after be absorbed and metabolized, and the saponin extract can inhibit the expression of
tumor cells VEGF and CD34 so as to inhibit the growth of capillaries of a
tumor tissue and then inhibit the growth of a tumor. A
plant source of the extract is a unique
plant species, which has great development and utilization value, is planted in a certain scale and is cheap and easily obtained, in Guangxi province. The invention provides an antitumor extract with a wide prospect, so that a novel medicament for treating tumors is provided.