Preparation method of plantago seed polysaccharide extractive and applications thereof
A technology of psyllium polysaccharides and extracts, applied in medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc.
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0023] Take about 2 kg of plantago medicinal material, reflux extraction with 90% ethanol for 3 times, 2 hours each time, filter, dry the filter residue, add 12 times the amount of distilled water to the residue, reflux extraction 3 times, 2 hours each time, filter, combine the filtrate, and decompress Recover the solvent to 1 times the volume of the medicinal material, adjust the alcohol content to 80% with 95% ethanol, let it stand overnight, centrifuge at 2000rpm / min, and wash the precipitate with 4 times the amount of absolute ethanol and acetone in turn to obtain the total polysaccharide. The total polysaccharide was dissolved in water, and the supernatant was dialyzed with a dialysis bag with a molecular weight of 3500 for 48 hours. The dialysate was concentrated under reduced pressure to 1 volume of the medicinal material, and 95% ethanol was added to adjust the alcohol content to 80%. It was allowed to stand overnight and centrifuged at 2000rpm / min. The precipitate was ...
Embodiment 2
[0025] Take about 3 kg of plantago medicinal material, reflux extraction with 80% alcohol for 2 times, 3 hours each time, filter, dry the filter residue, add 10 times the amount of distilled water to the residue, reflux extraction 2 times, 3 hours each time, filter, combine the filtrate, and decompress Recover the solvent to 1 times the volume of the medicinal material, adjust the alcohol content to 85% with 95% ethanol, let stand overnight, centrifuge at 2000rpm / min, and wash the precipitate with 4 times the amount of absolute ethanol and acetone in turn to obtain the total polysaccharide. Take the total polysaccharide and dissolve it in water, dialyze the supernatant with a dialysis bag with a molecular weight of 7000 for 48 hours, concentrate the dialysate to 1 volume of the medicinal material under reduced pressure, add 95% ethanol to adjust the alcohol content to 85%, let stand overnight, centrifuge at 2000rpm / min, and precipitate Wash with 4 times the weight of absolute e...
Embodiment 3
[0026] Embodiment 3 is made transfusion
[0027] The total polysaccharides were further purified and separated by Sephacryl S300 and Sephadex G50 chromatography on agarose gel column: to obtain a polysaccharide extract with a purity of more than 98%, add an appropriate amount of solubilizer, grind, then add a small amount of water for injection to dilute, and mix well , and then add an appropriate amount of sodium chloride, dissolve and then add water for injection to the specified amount, filter, pot, and sterilize to obtain.
PUM
![No PUM](https://static-eureka-patsnap-com.libproxy1.nus.edu.sg/ssr/23.2.0/_nuxt/noPUMSmall.5c5f49c7.png)
Abstract
Description
Claims
Application Information
![application no application](https://static-eureka-patsnap-com.libproxy1.nus.edu.sg/ssr/23.2.0/_nuxt/application.06fe782c.png)
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com