The present invention provides a method for fabricating an
implant stent with therapeutic effects. The method of the present invention includes designing and delineating a pattern of the
implant stent, drilling a
thin metal sheet to form positioning holes,
cutting a desired pattern on the
thin metal sheet according to the designed pattern, drilling a hole on a line rib of the
stent to form a braided structure by a micro
discharge processor according to the desired pattern. Then, the stent is cleaned and polished by the electropolish to trim the edge and the
rough surface of the stent. Then, the biodegradable material, PLLA, PGA,
fibrinogen, the
polyurethane-
polyethylene oxide mixed with the
heparin or the combination thereof, is used for forming the mixed material with the high molecular weight, and is solved in a
solvent, wherein another grinded therapeutic
drug with the micro or the
nano size is added. The
drug can be As2O5, an anti-caner
drug, or an anti-
inflammation drug. The solution with the bioadsordable material having a therapeutic drug is atomized and sprayed on the outer and inner surfaces of the stent. Since a row of holes are arranged on the line rib of the stent, each hole is immersed into the solution due to the capillary phenomenon. When the solution is completely evaporated, the biodegradable and absordable material and the drug are coagulated to form a
solid and to strongly coat on the surface of the stent. When the stent is implanted into a
human body, the
solid layer is slowly degraded and released on the injured site, so that the vessel is prevented from
restenosis, and the
therapeutic effect is achieved. The stent can be fabricated by the precision
machine technology in Taiwan, so that the
implant stent with low cost and therapeutic effects is obtained.