51 results about "Bifurcation lesion" patented technology

Each arterial bifurcation lesion has a fingerprint-like pattern related to varying amounts of plaque and degree of obstruction in the main vessel proximal to, within the bifurcation itself, and the distal limbs of the main branch and side branch(es) and related to the angle of the bifurcation. A new device and with it a new technique is described to optimize treatment of bifurcation (and trifurcation) lesions. The invention and related method use a catheter capable of delivering two or more guide wires exiting at the distal end of the catheter allowing treatment of lesions more safely and efficaciously. Safety is increased by allowing both guide wires to remain in place throughout the entire procedure. Efficacy is increased, particularly in the long-term, by providing a result that maximizes vessel coverage and normal flow dynamics in the entire bifurcation area. Contemplated is the use not only of multiple guide wires but also modified balloon with a tapered design to optimize flow dynamics at the bifurcation in the final result.

A catheter system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

The present invention is directed to a device comprising a catheter tube, which includes a round opening and two platinum radio-opaque markers on its distal end; a guide-wire; a balloon, which includes a wedge-shaped opening; and a stent, which includes an elliptical-shaped opening and three platinum radio-opaque markers. The invention is also directed to methods for using the device for deploying stents to treat bifurcation lesions.

A stent delivery system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

A balloon catheter for use in treating a condition of a vessel occurring near a bifurcation defined by the intersection of a main vessel with a side branch vessel comprises a shaft which comprises a proximal end, a distal end, a longitudinal passageway extending between the proximal and distal ends, and a transverse hole extending from the passageway. The balloon catheter also comprises a balloon head which is mounted on the shaft and which comprises an elongated balloon portion having a generally uniform outer diameter surface, an intermediate portion secured to the shaft proximate the hole, a port formed in the intermediate portion in alignment with the hole, and a portal extending between the outer diameter surface and the intermediate portion. In this manner, a proximal end of a first guide wire which is pre-positioned in the main vessel may be inserted into the distal end of the shaft and threaded through the longitudinal passageway and out the proximal end of the shaft, and a proximal end of a second guide wire which is pre-positioned in the side branch vessel may be inserted into the portal, the port and the hole and threaded through the longitudinal passageway and out the proximal end of the shaft.

A stent delivery system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

A catheter system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

The present invention provides a dilatation and stent delivery device which tracks over two guidewires. One guidewire is disposed in each branch vessel of a bifurcation. The present invention provides a dilatation and stent delivery device which enables efficient and accurate stent deployment and dilatation of bifurcation lesions.

A stent for ostial lesions and vascular bifurcations has a tubular body comprised by a succession of sections of skeletal members. In one or both end rows of the tubular body, there are expansive bending devices comprising sectional weakenings and open extremities. In the case of the end row, by a proper expander balloon, expansive bending of longitudinal branches of the end row may be produced. Bending is produced due to sectional weakenings. Open extremities allow producing the expansion in a way such as the flourishing of a flower bloom. Under such conditions, bending of the end row makes possible the adequate coverage of the ostial or bifurcation lesion affecting wall of the application vascular conduit.

The present invention provides a dilatation and stent delivery device which tracks over two guidewires. One guidewire is disposed in each branch vessel of a bifurcation. The present invention provides a dilatation and stent delivery device which enables efficient and accurate stent deployment and dilatation of bifurcation lesions.

The invention discloses a balloon catheter assembly for delivering nano-carriers to bifurcation lesions in one or more of a main branch and a side branch of a blood vessel bifurcation within 30 to 90 seconds. The balloon catheter assembly includes two or more balloons designed for use in the blood vessel bifurcation. A surface of one or more of the two or more balloons is coated with the nano-carriers. The nano-carriers include one or more drugs encapsulated with one or more biological agents.

The invention relates to a partially covered stent used for treating bifurcation lesion coronary perforation and provided with a biological absorption film. The partially covered stent comprises a stent body composed of a tubular inner layer stent and a tubular outer layer stent, wherein the tubular inner layer stent and the tubular outer layer have identical length concentric line engraved nettedstructures, a tubular covering film is clamped between the inner layer stent and the outer layer stent, and the partially covered stent is characterized in that one end of the covering film is flushwith the stent body, and the length of the covering film accounts for 30-50% that of the stent body; the covering film is the biological absorption film; the biological absorption film is a poly-DL-lactic acid film. The partially covered stent has the advantages of being capable of covering a blood vessel perforation part to form a complete blood flow channel, effectively preventing closing and plugging of side branches, meanwhile easily realizing endothelialization in a stent body, and effectively reducing forming of thrombi.

A catheter system for treating lesions is provided. The system is suitable for treatment of bifurcation lesions, has a low profile and provides substantially predictable translational and rotational positioning. In one embodiment, the system includes a fixed wire balloon catheter and a partially attached guidewire lumen, wherein the guidewire lumen is attached to the catheter at a crotch point. The location of the crotch point is predetermined so as to provide substantially predictable positioning. Several embodiments of the system are described for various types of lesions and vessel configurations.

The invention discloses a novel balloon dilatation catheter for cardiovascular disease treatment in the field of medical instruments. The novel balloon dilatation catheter comprises a balloon, an inner tube, an outer tube, development marks, a stress diffusion tube and a connecting device. The balloon is divided into five segments including a first cone segment structure, a second cylinder structure, a second cone segment structure, a second cylinder structure and a third cone segment structure in sequence from the distal end to the proximal end. According to the novel balloon dilatation catheter, for the overall structure of the balloon, the diameter of the first cylinder structure is small, and the diameter of the second cylinder structure is large, so that it is avoided that when a dilatation operation is performed, the distal end of a bifurcation lesion blood vessel is dilated excessively, and consequently the blood vessel is damaged, or the proximal end of the bifurcation lesion blood vessel is not dilated sufficiently, and consequently the effect of the dilatation operation is affected, the adherence effect is better, and the probability of occurrence of postoperative thrombus or restenosis is reduced; by adopting the segmental structure design, the blood vessel or lesion penetrating performance of the balloon dilatation catheter can be improved.

The invention belongs to the field of medical instruments and discloses a special-type main branch balloon stent system for bifurcation lesion interventional therapy. The system comprises a main branch balloon body provided with a side branch channel, a main branch balloon catheter head end penetrates into the main branch balloon body, and the portion, inside the main branch balloon body, of a main branch balloon catheter is provided with a guide wire inlet which is communicated with the side branch channel. The special-type main branch balloon stent system for bifurcation lesion interventional therapy is accurate in positioning, convenient to operate and capable of well fitting the blood vessel wall, thereby attaining good clinical application effect.

The invention relates to the technical field of medical equipment, in particular to a heart stent and a heart stent conveying and releasing device. The heart stent is suitable for bifurcation lesion and comprises a main stent body and a branch stent body which are matched with each other, wherein a butt joint opening is formed in the main stent body, a first end surface of the branch stent body is inclined, and markers are formed at the butt joint opening and on the first end surface, positioning is performed through cooperation of the first end surface of the branch stent body and the butt joint opening formed in the main stent body, the operation is simple, complete lesions are covered, excess metal wires affecting a branch opening are avoided, and butt joint is more precise. Each of a main stent body conveying mechanism and a branch stent body conveying mechanism of the heart stent conveying and releasing device is equipped with double guide wire tubes, and positioning is more accurate.

The invention discloses a balloon catheter assembly for delivering nano-carriers to bifurcation lesions in one or more of a main branch and a side branch of a blood vessel bifurcation within 30 to 90 seconds. The balloon catheter assembly includes two or more balloons designed for use in the blood vessel bifurcation. A surface of one or more of the two or more balloons is coated with the nano-carriers. The nano-carriers include one or more drugs encapsulated with one or more biological agents.

The invention provides an analysis method of plaque load in bifurcation lesion, which comprises: based on IVUS image, plaque is divided into regions, and the plaque load in each region is calculated.The present invention provides the analysis method of plaque load in bifurcation lesion; unlike the convention method that the whole plague load is generally calculated with the vessel where the plague is located, the method establishes an orthogonal coordinate system according to the relative position of the main branch blood vessel and the branch blood vessel, and divides the plaque load into regions; through the quantitative analysis method of region division, doctors can find the correlation of prognosis cause by the treatment method of different plaque loads and bifurcation lesion and find the optimal treatment method through evaluation, so the method has an important application prospect in clinical research.

The present invention relates to a stent for protecting a branch blood vessel at a branch-point lesion. The stent is inserted into and widened in a main blood vessel having the branch blood vessel extending in a slant from the branch-point lesion, thereby simultaneously expanding the main blood vessel and providing a smooth flow of blood towards the branch blood vessel. As a result, it is possible to simultaneously expand the main blood vessel and to sufficiently secure a passage from the main blood vessel towards the branch blood vessel. As such, the flow of blood is kept smooth. Further, after the stent is inserted into the main blood vessel, another stent, a guide wire, and related tools and catheter can be inserted in the direction of the branch blood vessel in a more accurate manner.

The invention discloses a child and mother guide conduit and a child conduit thereof. The child conduit comprises a conduit body and a conduit seat, wherein one end portion of the conduit body away from the conduit seat is provided with an end wall, the inner side of the end wall is an inclined face, an intersection angle between the inclined face and a shaft line of the conduit body is an acute angle, a side hole is formed in the side wall of the conduit body, and a guide wire can slide to the side hole along the inclined face. When bifurcation lesion occurs, the mother conduit is stretched into a main blood vessel, and then the child conduit moves along the mother conduit till the child conduit stretched out of the mother conduit and the side hole of the conduit body of the child conduit is opposite to a branch blood vessel, and then the guide wire is stretched into the child conduit till the end portion of the guide wire is offset with the end wall of one end of the conduit body away from the conduit seat, the end portion of the guide wire can slide to the side hole along the inclined face, and therefore the guide wire is entered into the branch blood vessel through the side hole, and accordingly medical apparatus and instruments such as a coronary artery saccule and a support and the like can be fed into the branch blood vessel for an operation.

A deployment apparatus and method for deploying one or more stents to a bifurcated vessel is provided. The invention is particularly suited for T-type bifurcated vessels where a side branch extends from a main branch. The deployment apparatus has a primary inflatable portion for engagement within the main branch and a secondary inflatable portion for engagement within the side branch. A main stent is arranged on the primary inflatable portion and radially expanded within the main branch while the secondary inflatable portion maintains registration with the side branch. A side branch stent is then arranged on the secondary inflatable portion and expanded within the side branch while the primary inflatable portion maintains registration with the expanded main stent. A bifurcated stent system suitable for bifurcated lesions is also provided comprising a side branch stent with a shaped end designed to engage a similarly shaped side opening in a main stent.

The invention relates to the technical field of medical instrument, in particular to a heart stent and a heart stent conveying and releasing device. The heart stent of the invention is suitable for bifurcation lesions and comprises a main stent and a branch stent mating with each other; the main stent is provided with a butt opening, a first end face of the branch stent is inclined, the butt opening and the first end face are marked, and the first end face of the branch stent cooperates with the butt opening of the main stent to perform positioning; the heart stent and the heart stent conveying and releasing device are simple to operate, can cover all lesions, has no excessive metal wires affecting a branch opening, and provides more precise butting. Conveying mechanisms of the main stentand branch stent are provided with a double-guide screw tube, and more accurate positioning is provided.

Provided in the invention is an OCT three-dimensional visualization system based on coronary artery bifurcation lesions. The system comprises an OCT image acquisition module, a real-time position tracking module, an image space position correction module, a blood vessel bifurcation registration fusion module and a three-dimensional rendering module. Besides, a working method comprises the steps ofOCT image acquisition, correction, data splicing and fusion, blood vessel inner wall information extraction, rendering and three-dimensional reconstruction. The system is simple in structure and easyto implement; an external electromagnetic wave generating device is not relied on, the cost is low and the anti-interference capability is strong; the visualization effect is good; and the accuracy is high.

Each arterial bifurcation lesion has a fingerprint-like pattern related to varying amounts of plaque and degree of obstruction in the main vessel proximal to, within the bifurcation itself, and the distal limbs of the main branch and side branch(es) and related to the angle of the bifurcation. A new device and with it a new technique is described to optimize treatment of bifurcation (and trifurcation) lesions. The invention and related method use a catheter capable of delivering two or more guide wires exiting at the distal end of the catheter allowing treatment of lesions more safely and efficaciously. Safety is increased by allowing both guide wires to remain in place throughout the entire procedure. Efficacy is increased, particularly in the long-term, by providing a result that maximizes vessel coverage and normal flow dynamics in the entire bifurcation area. Contemplated is the use not only of multiple guide wires but also modified balloon with a tapered design to optimize flow dynamics at the bifurcation in the final result.

The invention provides a bifurcated balloon, comprising an inflatable main branch balloon, a side branch balloon, a main branch inner catheter, a side branch inner catheter, and a developing ring; the side branch balloon is arranged on the side of the main branch balloon on the wall and communicate with the main branch balloon; the main branch balloon is sheathed on the outer catheter, and the proximal and distal ends of the main branch balloon are sealed with the outer catheter, and the distal end of the side branch balloon is sealed with the inner catheter of the side branch. Reduce damage to blood vessels, simplify the implantation process of the stent, and reduce the difficulty and cost of the operation; the use of main and side branch balloons with different diameters can improve the wall-attachment performance of the balloon, avoid excessive expansion of the distal end of the stent, and reduce The risk of postoperative thrombosis and restenosis; bifurcated balloon drug loading can reduce the inflammatory response of the endothelium, shorten the healing time of the endothelium, and reduce the risk of thrombosis. At the same time, without affecting the blood flow at the bifurcation, shortening the radiation exposure time and reducing the amount of contrast agent can improve the success rate and safety of treating bifurcation lesions.

The present invention discloses a microcatheter, with tubular structure, comprising a catheter body, a sharp portion disposed at a distal end of the catheter body, the catheter body comprises: a inner layer with a hollow lumen; a tubular intermediate layer wrapped outside the inner layer, comprising a spring layer and a braid above the spring layer, the braid extending longitudinally along a part of the spring layer; and a tubular outer layer, wrapped outside the intermediate layer; the part of the spring layer which is not wrapped by the braid is bent at a certain angle along a longitudinal axis of the catheter body. The catheter body of the microcatheter of the invention is configured to have a multilayered structure, and the braid is only wrapped on spring layer near to the proximal end; the part of the spring layer not wrapped by the braid can be bent at a corresponding angle to adapt to an angle between the main branch and the branch of the coronary artery, to make sure that the microcatheter can reach the bifurcation lesions of the coronary artery.

The invention discloses a degradable stent system for bifurcation vascular lesions. The system comprises a degradable stent and a special-shaped balloon, wherein the degradable stent comprises a mainbody supporting part and an opening outer expanding part which is arranged on the main body supporting part and can be anchored and attached to the joint of a main blood vessel and a branch blood vessel; the special-shaped balloon comprises a balloon main part and a balloon branch part; the balloon main part extends along the main blood vessel, arranged on the inner side of the main body supporting part and used for supporting outer expanding of the main body supporting part so that the main body supporting part can be attached to the main blood vessel; the balloon branch part extends along the branch blood vessel and can support outer expanding of the opening outer expanding part. According to the degradable stent system, plastic deformation is generated through the opening outer expanding part, and the opening outer expanding part is tightly attached to the wall of the branch blood vessel, so that obstruction of a mesh structure to blood flow at the branch blood vessel is avoided, stent displacement under long-term blood flow impact is avoided, the stent posture correcting effect under complex lesions is achieved, and the accuracy of stent positioning in the operation process isimproved.