31 results about "ASPIRIN TABLETS" patented technology

The invention relates to a tablet capable of being chewed or disintegrated in the oral cavity, which comprises an enteric coated aspirin active ingredient, and preferably a lightly compressed matrix comprising directly compressible carbohydrate(s) and at least one sweetener.

The present invention discloses aspirin dipyridamole sustained-release tablets and a preparation method thereof, wherein the aspirin dipyridamole sustained-release tablets comprise an aspirin tablet core, an isolation layer coating, dipyridamole total mixing particles, and a protection layer coating. According to the present invention, the isolation layer is arranged between the dipyridamole layer and the aspirin layer so as to prevent production of the aspirin degradation product salicylic acid due to contact of the aspirin and the dipyridamole; the dry mixing method is adopted when the aspirin total mixing particles are prepared so as to avoid production of salicylic acid due to direct contact of the aspirin and water; and the tableting process of the preparation method of the present invention only requires the one core coating tableting equipment, and other processes can be achieved through the conventional equipment, such that the cost of the aspirin dipyridamole sustained-release tablets is not added while the aspirin stability can be ensured.

The invention provides aspirin composition freeze-dried tablets and a preparation method thereof, and relates to the technical field of medicine and medicine production. The aspirin composition freeze-dried tablets comprise aspirin, starch and sucrose, wherein starch and sucrose are used as accessories. Ordinary corn starch is treated by a heating process, so that the bonding and disintegration effects of starch in the tablets can be improved, and the forming property of the tablets can be improved; only starch and sucrose are required to be used as the accessories of the aspirin composition freeze-dried tablets. A two-cooling two-heating freeze-drying process is adopted for the aspirin composition freeze-dried tablets, and by twice cooling and twice heating, better forming property of the tablets can be achieved, and the dissolubility of the tablets is improved, so that the bioavailability of the tablets is improved. According to the tablets, the defects of ordinary aspirin tablets are overcome, the sort and using amounts of the accessories in the aspirin tablets are reduced, the tablets are high in dissolubility and bioavailability, and the curative effects and safety of clinical mediation are ensured.

The invention relates to a compatible preparation of a traditional Chinese medicine component and a western medicine for treating gastric cancer. The traditional Chinese medicine component is prepared from the following raw materials by weight: 10-20g of ginseng, 15g of poria cocos, 15-20g of pericarpium citri reticulatae, 10-20g of scorpion, 60-70g of astragalus membranaceus, 2 centipedes, 30-40g of coix seed and 20-30g of hawthorn; and the western medicine component comprises 3-4 aspirin tablets and 3-4 luminal tablets. The preparation is prepared by the following steps: decocting the traditional Chinese medicinal raw materials with water, and concentrating to obtain 100ml of decoction; grinding the western medicine tablets into powder, and dissolving the powder in the concentrated decoction. The preparation has the effects of tonifying qi, strengthening spleen, softening hard lumps and dispelling nodes, strengthening body resistance to resist cancers, activating blood circulation to remove stasis, clearing heat and removing toxicity. The preparation has the advantages of strict compatibility, simple medicinal materials with high effect, and is capable of removing diseases and cancers, promoting appetite and prolonging lives.

A slow-release aspirin tablet for treating transient cerebral ischemia attack, myocardial infarction, thrombosis, unstable angina pectoris, etc is proportionally prepared from aspirin, starch, hydroxypropyl methylcellulose, polyacrylic resin No.2, white dextrin, tartaric acid, tween-80 and alcohol. Its preparing process is also disclosed.

The invention relates to a tablet containing clopidogrel sulfate and aspirin active compositions and a preparation method thereof, and belongs to the technical field of medicines. The prescription is mainly composed of the active compositions clopidogrel sulfate and aspirin and other auxiliary materials. The usage amount of raw materials and auxiliary materials in per 1000 clopidogrel-sulfate aspirin tablets: 98 g of clopidogrel sulfate, 50.0 g-100.0 g of aspirin, 110.2 g-130.0 g of mannitol 200SD, 30.0 g-60.0 g of corn starch, 60.0 g-80.0 g of microcrystalline cellulose, 3.0 g-6.0 g of polyethylene glycol 6000, 2.0 g-4.0 g of hydrogenated castor oil, 3.0 g-6.0 g of stearic acid, 8.0 g-12.0 g of micropowder silica gel, and 15.0 g-20.0 g of low-substituted hydroxy propyl cellulose. The preparation technology of the prescription comprises weighing all raw materials and all internally-added compositions, mixing uniformly and granulating by using a dry process, adding all externally-added compositions after the dry-process granulating yield is calculated out, then utilizing a double-layer tablet press for tablet pressing, and finally employing an alcohol water solvent (alcohol/water=80/20) to prepare a dressing liquid for dressing. Compared with common single prescriptions clopidogrel sulfate tablet and aspirin tablet, the disclosed tablet containing clopidogrel sulfate and aspirin active compositions helps to reduce drug administration frequency of a patient, improve adaptability of a patient, and has synergic effect and relatively good curative effect by simultaneously using the two active compositions.

The invention relates to the field of pharmaceutical engineering, in particular to an aspirin enteric-coated tablet and a preparation method thereof. The preparation method of the aspirin enteric-coated tablet comprises the following steps that a first enteric coating layer and a second enteric coating layer are sequentially arranged outside an aspirin tablet core without a solvent. The first enteric coating layer is a coating layer obtained after the first coating layer is sprayed to the aspirin tablet core. Each first coating solution is prepared from, by weight, 1.8-2.2 parts of enteric coating materials, 0.2-0.4 parts of plasticizer, 0.8-1.2 parts of anti-sticking agent and 20-25 parts of solvent. By arranging the first enteric coating layer and the second enteric coating layer to wrapthe aspirin tablet core, external moisture infiltration can be effectively prevented, aspirin hydrolysis is prevented, and meanwhile the phenomenon that aspirin disintegrates in gastric juice is prevented, but the disintegration and dissolution effects of the aspirin in the gastric juice can be guaranteed.

The invention provides an arginine aspirin tablet and a preparation method thereof, relating to the field of medical technology, including arginine, aspirin, starch slurry, powdered sugar, dextrin, pregelatinized starch, calcium sulfate dihydrate, and microcrystalline cellulose , Tannic Acid, Magnesium Stearate, Sodium Alginate, Absolute Ethanol. The present invention uses arginine aspirin as the active ingredient and adds a variety of adjuvant components. Compared with other related dosage forms of aspirin, the present invention has better solubility, faster drug effect and more complete absorption, and arginine inhibits platelets of aspirin The aggregation effect has a synergistic effect, and at the same time it can resist the side effects of aspirin gastric mucosal damage and protect the gastric mucosa; it greatly increases the stability of arginine aspirin tablets, prolongs the storage period of arginine aspirin tablets, and is convenient for mass production. Mass production, and the manufacturing process is simple and the cost is low.

The invention provides an aluminum-magnesium-aspirin tablet (II) and a preparation method thereof. The aluminum-magnesium-aspirin tablet (II) is a double-layer tablet composed of an aspirin layer and a buffer layer, raw materials of the aluminum-magnesium-aspirin tablet (II) comprise an aspirin layer composition and a buffer layer composition, and the mass ratio of the aspirin layer composition to the buffer layer composition is 0.8: 1.2-1.2: 0.8; and wherein in the aspirin layer composition, 80% w/w of aspirin is coated with a premixed coating agent. According to the aluminum-magnesium-aspirin tablet (II) provided by the invention, the content of free salicylic acid is below 0.41% through 6-month accelerated stability investigation and test, and the tablet is free of phenomena such as layering and good in stability.

The invention relates to a compound dipyridamole and aspirin tablet and a preparation method thereof, and belongs to the technical field of medicine preparations. The tablet adopts a two-layer tablet which contains a dipyridamole tablet core and an aspirin tablet core and releases dipyridamole and aspirin in different portions, wherein the dipyridamole is slowly released for 12 h, and the aspirin is quickly released in the intestinal fluid. According to the tablet, the solubility and absorption degree of the dipyridamole in the gastrointestinal fluid can be significantly improved to improve the bioavailability of the dipyridamole, generation of relative substances can be effectively inhibited, the aspirin can be primarily and quickly released in the intestines to achieve the effect, the dipyridamole can be slowly released to achieve a long-acting effect, and therefore the treatment purpose of cooperative administration through slow releasing of the dipyridamole and quick releasing of the aspirin is achieved.

The invention provides a pharmaceutical composition of clopidogrel hydrogen sulfate and an acetylsalicylic acid tablet and a preparation method thereof, belonging to the field of pharmaceutical preparation. According to the pharmaceutical composition of clopidogrel hydrogen sulfate and the acetylsalicylic acid tablet provided by the invention, F-Melt is added into the formula, so that the flowability of materials is improved and the materials are uniformly mixed; and meanwhile, clopidogrel hydrogen sulfate and the acetylsalicylic acid tablet are respectively pressed into double-layer tablets, so that the two components are prevented from interacting, thereby benefiting the safety of clinical medication and the stability in the storage process.

The invention discloses a capsule for treating varicosity. The capsule is prepared from the following raw materials of radix notoginseng, Chinese angelica root, safflower, radix puerariae, folium ginkgo, radix astragali seu hedysari, wheat seedling juice, aspirin tablet and an empty capsule body. The capsule disclosed by the invention has the beneficial effects: (1) from a pathogenesis reason, self functional defects are improved, and under assistance of dredging medicine, the problem of varicosity of a patient can be completely solved; (2) the varicosity is not prone to relapsing, and the capsule is safe and has no side effects.

A kit and method for treating migraine headaches comprising the preparing of an oral composition containing at least two bags of black pekoe tea brewed in approximately three ounces of boiling water for ten to thirty seconds. After brewing, the bags of tea are removed and two 325 mg aspirin tablets, one to two teaspoonfuls or tablets of apple cider vinegar, and one to three teaspoonfuls of honey are mixed into the brewed tea. The entire hot and concentrated composition is then cooled over ice so that a person suffering from a migraine headache may quickly drink it.