221 results about "Aniline Compounds" patented technology

Novel thiazole aniline compounds, pharmaceutical compositions, methods of making them and uses thereof in treating M3 muscarinic acetylcholine receptor mediated diseases are disclosed.

The present invention relates to a novel class of disubstituted aniline compounds. These compounds can inhibit histone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and / or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and / or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo.

Aniline compounds useful as ashless TBN sources for lubricating oil compositions that are compatible with fluoroelastomeric engine seal materials, and lubricating oil compositions containing such aniline compounds.

The present invention aims to provide a laminate for a laminated glass which is used as a head-up display (HUD) and is not deteriorated even if exposed to light, and with which a laminated glass having excellent impact resistance can be prepared.The present invention pertains to a laminate for a laminated glass, wherein an interlayer film for a laminated glass and a retardation element sandwiched between adhesive layers are laminated, the interlayer film for a laminated glass contains a thermoplastic resin and an ultraviolet absorber, the interlayer film for a laminated glass contains, as the ultraviolet absorber, a benzotriazole compound or a benzophenone compound, and at least one compound selected from the group consisting of a malonic ester compound, an oxanilide compound and a triazine compound, the sum of the contents of the malonic ester compound, the oxanilide compound and the triazine compound is 0.8 parts by weight or more and the sum of the contents of the benzotriazole compound or the benzophenone compound is 0.8 parts by weight or more with respect to 100 parts by weight of the thermoplastic resin and the adhesive layer contains an adhesive having a glass transition temperature of −20° C. or lower.

The invention discloses a method for preparing active dye, namely active deep-red C-D by utilization of a microreactor, comprising the following steps that: J acids are coupled with diazonium salts of ethyl sulfone sulfate ester aniline compounds which contain sulfonic group, methyl, methoxyl group, ethyl group or oxyethyl group, and then active deep-red C-D azo dye is obtained; the coupling temperature is between10 and 25 DEG C and the pH value is equal to 1.5 - 6.5; the microreactor is adopted during the reaction process; a plurality of parallelly connected microchannels with diameter of between 10 and 500 micrometers are arranged inside the microreactor and both ends of the microchannels have shell covers. The product has good vividness, stable performance, good reproduction quality, high dye yield, good deep dyeing property and high fixation rate. The structural formula of the active deep-red C-D is as above, wherein, R1 and R2 are equal to H, SO3H, CH3, OCH3, OC2H5 and C2H5.

The present invention relates to a novel class of disubstituted aniline compounds. These compounds can inhibit hi-stone deacetylase and are suitable for use in selectively inducing terminal differentiation, and arresting cell growth and / or apoptosis of neoplastic cells, thereby inhibiting proliferation of such cells. Thus, the compounds of the present invention are useful in treating a patient having a tumor characterized by proliferation of neoplastic cells. The compounds of the invention may also be useful in the prevention and treatment of TRX-mediated diseases, such as autoimmune, allergic and inflammatory diseases, and in the prevention and / or treatment of diseases of the central nervous system (CNS), such as neurodegenerative diseases. The present invention further provides pharmaceutical compositions comprising the compounds of the instant invention and safe dosing regimens of these pharmaceutical compositions, which are easy to follow, and which result in a therapeutically effective amount of these compounds in vivo.

This application discloses methods for treating, preventing and / or alleviating the symptoms of type II diabetes and diabetes-related disorders or complications. The invention provides a novel approach to treating and managing disorders and symptoms related to elevated plasma glucose concentrations and insulin resistance, characterized by few side effects and low toxicity. In particular, the invention provides 2-hydroxy-benzoic anilide compounds and derivatives, and compositions thereof, which can control blood-glucose and increase insulin sensitivity by reducing plasma glucose concentration and cellular energy efficiency.

The invention discloses cyclodextrin-modified hypercrosslinked resin and a method for adsorbing and recovering aniline compounds in industrial wastewater by using the same. The method is used for adsorbing aniline compounds such as aniline, p-toluidine, p-chloroaniline and p-aminobenzoic acid in wastewater by taking the synthesized cyclodextrin-modified polystyrene-chloromethylstyrene hypercrosslinked resin as an adsorption material, and the maximum adsorption capacities can respectively reach 149mg / g, 198mg / g, 294mg / g and 623mg / g. Experimental results show that the adsorption capacity is obviously higher than the maximum adsorption capacities of adsorption materials such as activated carbon, coal ash and modified zeolite to the aniline compounds. The method disclosed by the invention has the advantages such as simple material preparation process, repeated utilization, mild adsorption condition, energy saving, environment friendliness and low cost.

To attain a composition for measuring residual chlorine concentration capable of preventing crystallization of a coloring reagent in a chemical solution under temperature conditions of 5° C., provided is a composition for measuring residual chlorine concentration in sample water including one or more coloring reagents selected from the group consisting of a dialkyl benzidine compound and a tetraalkyl benzidine compound, an acid, and an alcohol compound. The alcohol compound is selected from the group consisting of a monohydric alcohol, a dihydric alcohol, and a trihydric alcohol, for example, and the composition is prepared to contain the alcohol compound in a content by weight of 20 to 100 times that of the coloring reagent.

The invention discloses a method for simultaneously separating and detecting inorganic anions and aniline compounds in wastewater by a novel high performance liquid chromatography-ion chromatography two-dimensional system, belonging to the technical field of testing the material content by the high performance liquid chromatography-ion chromatography two-dimensional system. The liquid chromatography-ion chromatography two-dimensional system consists of a liquid chromatographic pump, an automatic sampler, an organic capture column, a liquid chromatographic column, an ion chromatographic column, a six-way valve, an ultraviolet detector and a conductive detector. The system is characterized in that inorganic anions and aniline compounds in wastewater can be simultaneously separated and detected by sampling at a time. When the inorganic anions and aniline compounds pass through a porous graphite carbon short column, the aniline compounds are strongly retained in the porous graphite carbon short column while the inorganic anions quickly enter the ion chromatographic column to be analyzed and detected by using the conductive detector; meanwhile, the aniline compounds are transferred to the liquid chromatographic system through a switching valve and are quickly detected by using the ultraviolet detector.

Aniline compounds useful as ashless TBN sources for lubricating oil compositions that are compatible with fluoroelastomeric engine seal materials, and lubricating oil compositions containing such aniline compounds.

Novel addition products of hydroxyl-protecting groups (such as isocyanates) with oxyalkylene-substituted intermediates, such as poly(oxyalkylenated) aniline compounds, for the eventual production of substituted, and substantially pure, colorants, particularly diazo and triphenylmethane derivatives, through the reaction of such intermediates with certain reactants are provided. These new colorants exhibit improved wax and / or oil solubility and high purity, particularly due to the inability of certain impurities to deleteriously react with the protected hydroxyl groups of either the intermediate or the colorant during and / or after formation thereof. A method for producing such novel colorants through utilization of these novel substantially pure colorant intermediates is also provided.