675results about How to "Reduced structure" patented technology

The invention provides immunoglobulin polypeptides comprising variant amino acids in CDRs of antibody variable domains. In one embodiment, the polypeptide is a variable domain of a monobody and has a variant CDRH3 region. These polypeptides provide a source of great sequence diversity that can be used as a source for identifying novel antigen binding polypeptides. The invention also provides these polypeptides as fusion polypeptides to heterologous polypeptides such as at least a portion of phage or viral coat proteins, tags and linkers. Libraries comprising a plurality of these polypeptides are also provided. In addition, methods of and compositions for generating and using these polypeptides and libraries are provided.

Provided are methods for making a device or device component by providing a multilayer structure having a plurality of functional layers and a plurality of release layers and releasing the functional layers from the multilayer structure by separating one or more of the release layers to generate a plurality of transferable structures. The transferable structures are printed onto a device substrate or device component supported by a device substrate. The methods and systems provide means for making high-quality and low-cost photovoltaic devices, transferable semiconductor structures, (opto-)electronic devices and device components.

The invention relates to a needle insertion device comprising a housing with a mounting surface adapted for application to the skin of a subject, where the mounting surface defines a general plane and has a needle aperture formed therein. Adhesive means is arranged on the mounting surface for adhering the insertion device to the skin of the subject, the adhesive means surrounding the needle aperture. A needle comprises a distal pointed end adapted to penetrate the skin of the subject, the pointed end being arranged within the housing in respect of the general plane. The mounting surface surrounding the needle aperture is moveable between a first position in which the pointed end of the needle is arranged within the housing, and a second position in which the pointed end of the needle projects through the needle aperture, thereby pulling the skin portion corresponding to the intended site of needle insertion against the needle.

The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries. In several aspects of the present invention, there are methods based on methylation-dependent enrichment or depletion of genomic DNA isolated from cellular and cell-free sources. In additional embodiments, there are methods and compositions for single-step high throughput preparations of Methylome libraries.

A driving apparatus for a DC brushless motor of a ceiling fan is provided. By setting at least one coder and one sensor outside the DC brushless motor, the driving apparatus can sense the position of magnetic poles of the motor for driving the motor. Meanwhile, a controller set with the motor stores the rotation speed of the motor before being turned off by detecting the turn-off time of a turn-on / off signal.

A magnetic resonance antenna has longitudinal antenna rods in a birdcage structure, and antenna ferrules connecting the longitudinal antenna rods at their ends in terms of radio-frequency. The magnetic resonance antenna has a number of radio-frequency switching elements that interrupt, in terms of radio-frequency, at least one part of the longitudinal antenna rod to detune the eigen-resonance frequency of the antenna with respect to an operating magnetic resonance frequency. For this purpose, the magnetic resonance antenna is provided with two switching lines, directed to the radio-frequency switching elements from outside of the birdcage structure, the switching lines having a ring line connected thereto running annularly on or in the birdcage structure and transverse to the longitudinal antenna rods.

Core drill bits with long crown heights are described herein. The core drill bits have a series of slots or openings that are not located at the tip of the crown and are therefore enclosed in the body of the crown. The slots may be staggered and / or stepped throughout the crown. As the cutting portion of the drill bit erodes through normal use, the fluid / debris notches at the tip of the bit are eliminated. As the erosion progresses, the slots become exposed and then they function as fluid / debris ways. This configuration allows the crown height to be extended and lengthened without substantially reducing the structural integrity of the drill bit.

A method of treating a vein comprises accessing a vein at an access point spaced from a sapheno-femoral junction. A bioabsorbable fibrous body is implanted into the vein through the access point. The body is moved in the vein toward the sapheno-femoral junction.

A method of treating a hollow anatomical structure of a patient comprises implanting a bioabsorbable fibrous body in a hollow anatomical structure. The body is secured in the hollow anatomical structure to limit migration of the body within the hollow anatomical structure.

A system and associated methods to determine an optimal radiation beam arrangement are provided. The system includes a computer planning apparatus which includes a treatment plan optimization computer having a memory and an input device in communication with the treatment plan optimization computer to provide user access to control functions of plan optimization software. An image gathering device is in communication with the treatment plan optimization computer through a communications network to provide an image slice of the tumor target volume and the non-target structure volume. The plan optimization software computationally obtains and then optimizes a proposed radiation beam arrangement iteratively based on constraints to form an optimized radiation beam arrangement. A conformal radiation therapy delivery device in communication with the treatment plan optimization computer through the communications network then applies the optimized radiation beam arrangement to the patient.

A puncture sealant supplying / removing apparatus includes a pressure-resistant bottle, an apparatus body on which the pressure-resistant bottle can be mounted, supply hose means which supplies or returns a puncture sealant accommodated in the pressure-resistant bottle to or from a tire, and a high pressure air source.The apparatus body comprises a venturi flow-path having a venturi portion, a first flow-path extending from the venturi portion into the pressure-resistant bottle, and a second flow-path extending from an inside of the pressure-resistant bottle and connected to one end of the supply hose means. The venturi flow-path is provided at its one end with an air intake which is connected to the high pressure air source, the venturi flow-path is provided at its other end with an opening / closing tool capable of opening and closing the other end.

In one embodiment, a method for forming a circuit comprises generating bonding data specifying locations for one or more electrically conductive bonding lines and generating one or more printing instructions based on the bonding data. The method further comprises, using the printing instructions, printing the one or more electrically conductive bonding lines substantially on a surface of a substrate, the one or more electrically conductive bonding lines operable to provide electrical conductivity between a first element of the circuit and one or more second elements of the circuit.

This invention is generally related to the field of Fischer-Tropsch catalysts. In particular, the present invention is related to a Fischer-Tropsch catalyst and method of making same. More particularly, the present invention discloses a catalyst comprising a support and at least one catalytically active metal wherein the support comprises a transition alumina including theta-alumina, delta-alumina, or combinations thereof, and a surface coverage comprising at least one rare-earth oxide.

An apparatus and method for implementing an equalizer which (1) combines the benefits of a decision feedback equalizer (DFE) with a maximum-a-posterori (MAP) equalizer (or a maximum likelihood sequence estimator, MLSE) (2) performs equalization in a time-forward or time-reversed manner based on the channel being minimum-phase or maximum-phase to provide an equalization device with significantly lower complexity than a full-state MAP device, but which still provides improved performance over a conventional DFE. The equalizer architecture includes two DFE-like structures, followed by a MAP equalizer. The first DFE forms tentative symbol decisions. The second DFE is used thereafter to truncate the channel response to a desired memory of L1 symbols, which is less than the total delay spread of L symbols of the channel. The MAP equalizer operates over a channel with memory of L1 symbols (where L1<=L), and therefore the overall complexity of the equalizer is significantly reduced.

Embodiments of the pertinent invention relates to apparatus, systems and methods for diagnostic testing of an electrochemical cell stack, such as a fuel cell stack or an electrolyzer cell stack. According to one embodiment, the apparatus comprises a multiplexer for switching current to one or more cells in the electrochemical cell stack, a voltage monitor for monitoring the voltage between the anode plate and the cathode plate of one or more cells, a power supply module for supplying power to the multiplexer and a gas supply module for supplying fuel gas and non-fuel gas to the electrochemical cell stack. The apparatus further comprises a control module electrically connected to and configured to control the multiplexer, the voltage monitor, the power supply module and the gas supply module to conduct automatic diagnostic testing of the electrochemical cell stack. The control module is further configured to determine, through the diagnostic testing, whether the electrochemical cell stack has one or more gas leaks. If one or more gas leaks is detected, the control module determines which of the one or more cells is affected by the gas leak. The control module is further configured to determine a degree of crossover of electrochemical reactant through the membrane of each cell and whether any of these cells is likely to be short-circuited.