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256results about How to "Non-allergenic" patented technology

Mask liquid with multiple skin care effects and preparation method thereof

The invention discloses mask liquid with multiple skin care effects and a preparation method thereof, aims at providing mask liquid which has effects of skin whitening, speckle removing, wrinkle smoothing, inflammation relieving and diminishing, long-lasting moisturizing and grease balancing, and belongs to the technical field of cosmetics. According to the technical scheme, the mask liquid is prepared from, by weight, 0.5%-3% of sericin, 3.011%-14.02% of a plant extract, 1.11%-8.35% of a moisturizer, 8%-15% of polyalcohol, 0.1%-1.5% of active peptides, 0.08%-0.15% of Carbomer, 0.08%-0.15% of triethanolamine, 0.02%-0.06% of disodium EDTA, 0.3%-0.5% of a preservative and the balance deionized water.
Owner:GUANGDONG BAWEI BIOLOGICAL TECH CO LTD

Gene recombination human collagen fusion peptide segment, preparation method and application thereof

The invention relates to a gene recombination human collagen fusion peptide segment. The overall length of the peptide segment comprises 839 amino acids, the nitrogen end of the peptide segment comprises a type III human collagen peptide section of 908-1137, which totally contains 229 amino acids, and the carbon end of the peptide segment comprises a type I human collagen peptide segment of 497-1104, which total contains 608 amino acids, wherein the two peptide segments are connected by using glutamic acid and phenylalanine. The preparation method of the peptide segment comprises the following steps of: constructing cDNAs of clone type I (COL 1) and type III (COL 3) human collagen genes and a Pichia pastoris recombinant expression vector pPOC9K-COL3a1-COL1a1; constructing Pichia pastoris genetic engineering bacteria SMD1168-COL3a10COL1a1 of the gene recombination human collagen fusion peptide segment; preparing the gene recombination human collagen fusion peptide segment, and the like. Proved by tests, the gene recombination human collagen fusion peptide segment prepared by adopting the method can be used as a material for preparing cosmetics.
Owner:SHAANXI HUIKANG BIO TECH CO LTD

External plaster for treating child cold type cough and preparing method

InactiveCN1899550AEnhance immune functionSolve the problem of needle and drug refusalAerosol deliveryOintment deliveryCurative effectTangerine Peel
The externally applied plaster for treating infantile cold type cough is developed on the infantile physiological and pathological characteristics and cough cause and is prepared with 13 kinds of Chinese medicinal materials, including purple perilla, hogfennel root, tangerine peel, eucalyptus leaf, etc. and through decoction, concentration, crushing, mix and other steps. It has the functions of dispelling wind and cold, opening the inhibited lung energy and relieving cough, regulating qi, etc. and is used to treat infantile cough caused by external wind and cold and dyspepsia due to improper feeding, and has obvious curative effect and high safety.
Owner:赤峰市福善堂医药有限公司

Method of modifying lactoalbumin by enzymatic method and its application

A process for modifying the lactoprotein by enzyme method features that the immobilized composite enzyme, the ionically regulatory protein structure and heat treating technique are used as selectively hydrolyze the alpha S-casein and beta-lactoglobulin in lactoprotein, resulting in easy digestion and low sensitization. It can be used for composite milk for baby, old man and patient.
Owner:YINGTAN HUABAO FLAVORS & FRAGRANCES

Color-protecting and fresh-keeping method for fresh-cut potatoes

The invention discloses a color-protecting and fresh-keeping method for fresh-cut potatoes. The method includes selecting fresh or stored potatoes as the raw material, washing cleanly, peeling, cutting into chips with thicknesses of 0.5-1.0mm, adding a composite color-protecting fresh-keeping solution having the same mass with the potato chips, and soaking for 10-30min at 20 DEG C-30 DEG C; then fishing out the potato chips from the composite color-protecting fresh-keeping solution, washing cleanly with water, soaking in water at 10-150w ultrasonic power and 10-50kHz ultrasonic frequency for 10-30min of ultrasonic time; fishing out the potato chips and draining off, processing for 10-30min under the condition of subzero 0.01MPa-subzero 0.09MPa of vacuum degree; and finally taking the potato chips out of the vacuum environment and soaking immediately into an arbutin solution with the concentration of 0.05-0.3mmol/L, soaking for 5-15min, taking the soaked potato chips out and draining for 1-3min, performing decompression packaging immediately, and storing at an environment of subzero 4 DEG C to zero DEGC. The method adopts ultrasonic and vacuum cooperative processing as well as the Chinese herb extract arbutin as the color-protecting fresh-keeping agent to inhibit enzyme and microbial activities, is better in effect compared with the prior art, and ensures that various potato processed products are prevented from brown stain in a cold storage process for more than 10 days.
Owner:SHANXI AGRI UNIV

Artemisinin derivatives freeze-dried preparation and preparation method

The present invention relates to a frozen dry preparation of drug artemisinin derivatives and the preparation method. The present invention is composed of artemisinin derivatives and water-soluble cyclodextrin derivatives, the weight ratio of the artemisinin derivatives and water-soluble cyclodextrin derivatives is 1: 30 to 70, the smashed artemisinin derivatives are added into the water solution of the water-soluble cyclodextrin derivatives at 50 DEG C to 90 DEG C for agitating and dissolving, then the frozen dry preparation is prepared by the conventional process of the injection and the frozen drying. The low-temperature micro-powder technology of the present invention has the advantages that the technology can ensure the physical and chemical properties of the artemisinin derivatives to be consistent before and after the smashing, the process is relatively simple compared with the prior art, the equipments make use of the existing production equipments of the company, thus saving the investment and shorten the production cycle; the dispensing solvent is the water for injection, without the organic solvents, surfactants and cosolvents, so as to improve the safety; the present invention is easy to be dissolved in water, and has fast dissolution speed and the infinite dilution stability, thus avoiding the secondary pollution caused in the other methods which firstly prepare the artemisinin derivatives into the inclusions by using the organic solvents and then sub-package the inclusions thereof.
Owner:KPC PHARM INC

External plaster for treating child cold diarrhea and preparing method

The present invention discloses a kind of externally applied plaster for treating children's cold type diarrhea and its preparation process. The externally applied plaster is developed based on children's physiological and pathological characteristics and the pathogenesis of cold type diarrhea, and is prepared with ten kinds of Chinese medicinal materials, including atractylodes rhizome, schizonepeta, bupleurum root, etc. and through decoction, concentration, crushing and other steps. It has the functions of invigorating spleen, eliminating wetness, regulating qi, etc. It has obvious curative effect on children's cold type diarrhea, use safety and convenient quality control.
Owner:赤峰市新州中药饮片有限责任公司

Levocarnitine for injection and preparation method thereof

The invention discloses a levocarnitine for injection and a preparation method thereof. The preparation method comprises the following steps: weighing sodium dihydrogen phosphate and sodium hydroxide, using injection water to dissolve the weighed sodium dihydrogen phosphate and sodium hydroxide and diluting and uniformly mixing, dissolving levocarnitine and mannitol in the buffer solution, addingneedle active carbon and stirring uniformly, stirring for adsorption, and using filtering membrane for filtering and removing carbon; carrying out fine filtration through 0.22 mum microporous membrane, after the intermediate passed the inspection, filling the filtrate with the amount of 5 ml in 15 ml penicillin bottle (using up the liquor in 6 h after degerming), and carrying out half-plug pressing, freeze-drying, capping, visual inspection, labeling, and packaging. According to the invention, buffer salts (the buffer salt ion pair consisting of sodium dihydrogen phosphate and sodium hydroxide) with buffer effect are used in stead of traditional hydrochloric acid to regulate the pH value of the levocarnitine solution, so that the main drug is always in a stable pH environment in the wholepreparation process, and the API degradation caused by violent change of pH value of levocarnitine is avoided. Compared with the similar kind products, the levocarnitine disclosed in the invention has higher effectiveness and higher safety.
Owner:长春海悦药业股份有限公司

Compound povidone iodine gel for treating mastitis of milk cattle as well as preparation method and application

The invention belongs to the technical field of animal remedy preparation and in particular relates to a pharmaceutical composition for curing dairy cow mastitis and a preparation method and a usage of the pharmaceutical composition. The remedy comes into being by mixing carbomer-940, povidone iodine, hydrocortisone, potash iodate, propylene glycol or glycerol, sodium hydroxide and purified water. The povidone iodine in the preparation has great sterilizing power, no odor or stimulation or sensitization and low toxicity and leads to no residuals which are formed in milk and harmful to human body, no withdrawal period is required during the course of medication, and no milk drinking stop is required; a prepared gel preparation is injected into breasts, a relatively high drug concentration can be achieved in the breasts in a short time, and the treatment cycle is short. Results of clinical trials show that the cure rate of recessive mastitis of the diary cow is up to 86.43 percent, and the effective rate is up to100 percent; and the cure rate of clinical mastitis of the diary cow is up to 78.03 percent, and the effective rate is up to 93.75 percent.
Owner:HUAZHONG AGRICULTURAL UNIVERSITY

Medical cold-compressing plaster and preparation method thereof

The invention provides a medical cold-compressing paster which comprises a back lining layer, a gel layer and a covering layer. The gel layer is prepared from raw materials, the raw materials include,by mass, 2%-15% of a polymer substance, 2%-10% of an epidermal growth factor, 2%-8% of ceramide, 3%-8% of a moisturizer, 3%-10% of a radix bupleuri extract, 2%-8% of a dandelion extract, 3%-12% of agolden cypress extract, 5%-10% of an aloe extract, 2%-10% of a honeysuckle flower extract and the balance purified water. The invention also provides a preparation method of the medical cold-compressing paster. The medical cold-compressing paster has the advantages that the medical cold-compressing paster is convenient to use; the medical cold-compressing paster achieves both cold-compressing cooling and pain relieving, also promotes organization healing; the biocompatibility is good, and the medical cold-compressing paster does not have sensitization and irritation; the drug release performance is good, and the application time is long; the medical cold-compressing paster provides different shapes, and the different demands are met; the preparation method is easy to operate, the raw materials are wide in source, the preparation cost is low, no toxic-side effect is produced, and the medical cold-compressing paster is safe and reliable.
Owner:SHANDONG ZHUSHI PHARMA GRP CO LTD
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