31results about How to "No obvious stimulating effect" patented technology

A liquid dressing for preventing the bacterial infection of skin wound by covering a film on the skin wound is prepared through high-temp reaction between methyl (and / or ethyl) methylacrylate and isooctyl acrylate to obtain a high-molecular polymer, and dissolving it in the polar solvent of ethyl acetate or the mixed solvent of ethyl acetate and n-hexane. Its advantages are air permeable and water-proof.

The invention discloses diclofenac diethylamine emulgel. In the emulgel, isopropyl myristate, isopropyl alcohol and propylene glycol are combined as a penetration enhancer; carbomer 980 is used as a water-based gel substrate matrix; liquid paraffin is used as an oil-phase matrix; and polysorbate 80 and glycerol monostearate / distearate are used as emulsifiers. The diclofenac diethylamine emulgel disclosed by the invention is high in in-vitro penetration absorption speed, takes effect quickly, and is favorable for easing the pain of a patient in time; and moreover, the diclofenac diethylamine emulgel has the characteristics of less skin irritation and high stability.

A composite agricultural chemical in the form of emulsified oil or suspension for preventing and elimianting plutella xylostella contains abamectin and malathion in the ratio of 1:(100-1000). Its advantages are high effect and low poison.

The invention provides a fullerene derivative, which is a fullerol shown by a general formula C60OxHy (y is more than 10 and less than or equal to x, and x is more than or equal to y and less than 50) or a fullerene carboxyl derivative shown by a general formula C60(C(COOH)2)n (n is an integral number of between 1 and 4), wherein the diameter range of nano-particles of the fullerene derivative in a solvent is between 1 and 400nm. The invention also provides application of the vaccine adjuvant of the fullerene derivative in the field of vaccines, and the vaccine adjuvant of the fullerene derivative has high safety, can remarkably improve the immunogenicity of the vaccine through different immune ways, and has great application prospect.

The invention relates to a liquid wound dressing for rapid repair of superficial skin damage and a preparation method thereof, which comprises: cytokine PDGF-BB, polyvinyl butyral, betaine-type surfactant, polyacrylic acid and deionized water. The liquid wound dressing provided by the invention can form a waterproof, breathable and bacteria-resistant protective film on the surface of the wound, which acts as a physical barrier to prevent bacteria and foreign matter from invading the wound and create a wound healing environment; after being applied, it can protect new tissues and accelerate wound healing effect.

A nimodipine injection composition and a preparation method thereof. The nimodipine injection composition comprises the following components in terms of mass concentration: 0.02-0.23% of nimodipine, 2-30% of oil for injection, 0.8-3% of emulsifier, and 0-0.1% of complexing agent , stabilizer 0‑0.3%, osmotic pressure regulator 1‑3%. The composition does not contain ethanol as a solubilizing agent, co-emulsifiers such as Tween-80, and co-solvents such as benzyl alcohol.

The invention discloses a poly(lactic-glycolic acid)-coated nano-adjuvant with an immunostimulator and catalase, which has obvious effects in radiotherapy and immunotherapy. Among them, catalase can effectively improve the hypoxic microenvironment of tumors and improve the effect of radiotherapy. At the same time, immune stimulants can guide immunotherapy in vivo. With the help of immune checkpoint blockers, the activity of regulatory T cells is inhibited. Inhibition has the effect of inhibiting tumor growth and metastasis. The invention also discloses the preparation method and application of the nano-adjuvant.

The invention relates to the technical field of pharmaceutical preparations, and particularly discloses an acyclovir emulsifiable paste and a preparation method thereof. The acyclovir emulsifiable paste comprises acyclovir, an oil phase substrate, an emulgator, a cosolvent, an acid-base buffer system, a humectant and water, wherein the oil phase substrate is a mixture of liquid paraffin, cetearyl alcohol and albolene, the cosolvent is poloxamer 188, and the acid-base buffer system is a citric acid-sodium hydroxide system. By combining the improvements of the formula and preparation method, the acyclovir can be dissolved in emulsifiable paste substrate, thus having better anti-herpes virus effect, high safety and good stability.

A synthetic method of environment-friendly urea moulding compound resin relates to urea formaldehyde and the synthetic method of modifying urea formaldehyde by tripolycyanamide. Firstly, a ph8-9 formaldehyde solution added with urea or urea and tripolycyanamide reacts under the temperature of 60 to 90 DEG C and when the reaction liquid turns into ivory-white thick liquid, water with the basicallysame pH value of the reaction liquid is added for even mixing or reaction under the temperature of 70 to 90 DEG C for 0.5 to 1.5 hours; then organic acid is used to adjust pH to 5-6 and further reaction goes on under the temperature of 70 to 90 DEG C; when the reaction liquid turns into ivory-white thick liquid; afterwards, sodium carbonate solution is used to adjust the pH of the reaction liquidto 7-8 and water with the basically the same pH value of the reaction liquid is added for even mixing; finally, the ivory-white thick resin liquid is sent to the sequent procedures and processed intothe urea moulding compound. In the method, excessive formaldehyde is converted into resin as much as possible, thus reducing the air pollution and protecting workers health; at the same time, the formaldehyde residue of the urea moulding compound is greatly reduced, so the present invention is worthy the name of environment-friendly process compared with the traditional process.