51results about How to "No sensitization" patented technology

The invention relates to a nanometer silver aqueous solution preparation. Its components and weight percentage are: nanometer silver 0.05-1.5, the dispersant 0.5-1.5, the reducer 0.05-0.2, the stabilizer is nanometer silver 0.5-1.5, the dispersant 0.5-1.5, the reducer is 0.05-0.2, the stabilizer is 0.5-10, and the deioned water is 1000. The invention also relates the manufacturing method for above mentioned nanometer silver aqueous solution preparation, and the usage for curing man social disease, and the using method for ejecting the medicine into bladder through urethra. The reducer and stabilizer in the solution accord with the standards of America FDA or china sanitary department.

The invention discloses a skin cleaner composition capable of regulating a microecological balance of skin. The raw material formula of the composition especially has the function of regulating the microecological balance of the skin by adding a composition of oligosaccharide and probiotic bacteria metabolites. By adopting the composition, not only can dirt on the skin be washed off, but also the skin can be moisturized and moistened, and the composition has the functions of proliferating beneficial bacteria on the skin surface, inhibiting harmful bacteria on the skin surface and maintaining normal ecological balance of the skin.

The invention relates to the technical field of daily care products, in particular to a washing-free foam type female bactericidal solution and a preparation method thereof. The washing-free foam type female bactericidal solution is prepared from natural plant saponins, a bactericidal odor removing agent, a nourishing and moisturizing agent, a plant anti-allergic anti-itching agent, a solvent, lactic acid, citric acid, sodium citrate, a solubilizer and ethyl alcohol. The washing-free foam type female bactericidal solution is a foam type care solution capable of being internally used and can have a larger surface area to make contact with skin; meanwhile, foam is not prone to overflow, and long-acting sterilization protection is achieved. The bactericidal solution can reduce damage to female physiological environment to the maximum extent and protect mucosa and skin of private parts from being injured. In addition, the bactericidal solution has killing and inhibiting effects on harmful germs in vaginas, has a protection effect on beneficial bacteria and maintains balance of normal flora at the female private parts.

The invention discloses a double-agent melanin precursor hair dye and a three-agent melanin precursor hair dye. The double-agent melanin precursor hair dye comprises an agent A and an agent B; the three-agent melanin precursor hair dye comprises an agent A, an agent B and an agent C; the agent A and the agent C both comprises melanin precursors, common hair dye auxiliaries and water; the common hair dye auxiliaries refer to one or more of a wetting agent, a thickening agent, a surfactant, a moisturizing agent and a pH value regulating agent. By combination of advantages of chemical synthesized hair dye and natural hair dye, compound enzyme liquor in natural edible fungi is extracted, amino acids are subjected to bioconversion to synthesize melanin precursor substances such as hallachrome, 5,6-dyhydroxyindole and 5,6-dyhydroxyindole-2-carboxylic acid, skin irritation and allergization are avoided, high safety is achieved, and natural black hair dyeing effects are kept. In addition, due to various agent type choices, the multi-agent melanin precursor hair dye has a great popularization and application value in the field of hair dye preparation.

The invention provides a new cefmetazole preparation used for injection. The preparation mixes evenly active ingredient cefmetazole acid asepsis powder and complex solubilizer anhydrous sodium carbonate asepsis powder which are respectively bottled in sterilized amoxicillin bottles according to labeled amount and are packaged to obtain the product of cefmetazole used for injection after tamponage, rolling of cover and full inspection; wherein the weight ratio between cefmetazole acid (pure) and anhydrous sodium carbonate is 1:0.1 to 1:0.2 with 1:0.15 being the better ratio, namely, 1g of cefmetazole acid (pure) asepsis powder is added into 0.1-0.2g of anhydrous sodium carbonate asepsis powder. The preparation is good in stability and safe in usage.

The invention discloses amygdalin gel and a preparation method and medicinal application thereof, belonging to medicinal preparations containing organic active components. The preparation method comprises the following steps of: adding distilled water to 1-15% of amygdalin as a medicinal material till dissolution; adding 0.5-10% of a high polymer host material carbomer for fully swelling; then respectively adding 1-25% of glycerol as a humectant, 0.5-20% of propylene glycol as a penetrating agent, 0.05-0.2per mill of ethyl p-hydroxybenzoate as a preservative and 0.01-0.2% of disodium ethylene diamine tetraacetate as a stabilizer; regulating the pH to 6.0-8.0 by 0.5-3% of triethanolamine; finally adding distilled water to 100%; and fully stirring to form gel. The amygdalin gel prepared by the preparation method has no irritation and allergization on skin, can release the medicament stably and persistently, and has high bioavailability and satisfactory percutaneous infiltration rate, so that the amygdalin gel becomes a new external medicinal preparation.

The invention provides a medical ultrasonic probe stelrizing gel and a preparation method thereof. The gel comprises the following components of 0.5-5 percent (w / v) of non-ionic cellulose material or 5-20 percent (w / v) of poloxamer, 0.1-0.5 percent (w / v) of chlorhexidine acetate, 0.1-0.5 percent (w / v) of double-chain quaternary ammonium salt sterilizing agent, 0.5-2 percent (v / v) of wetting agent and the balance of water. The sterilizing agent has the function of sterilizing and disinfecting a medical ultrasonic probe and the skin; and a soluble medical ultrasonic probe sterilizing gel with better acoustical property, safety and stability can be used as a coupling agent, can realize high-efficiency sterilization within short time and concurrent disinfection on the ultrasonic probe, and achieves the purpose of reducing cross infection risk caused possibly in the clinical ultrasonic detection process.

The coupling agent for B-mode ultrasound diagnostic instrument consists of povidone-iodine 0.5-5 %, glycerin 1-7 %, sodium carboxy methyl cellulose 3-6 %, ethanol 10-15 % and pure water 67-85.5 %. During its preparation, povidone-iodine is first dissolved in water, sodium carboxyl methyl cellulose and ethanol are mixed homogeneously through stirring, the povidone-iodine solution is then mixed with mixed sodium carboxy methyl cellulose and ethanol solution through stirring, and the mixed solution is 80-120 mesh filtered to obtain the coupling agent. The coupling agent is used in supersonic test in hospital and can kill bacteria and virus and prevent crossed infection.

The invention discloses a gel medical supply for preventing the bedsore and a preparation method thereof. The gel is prepared by uniformly mixing the following components: 0.05-0.5% of halogenated diphenyl ether or biguanide-type bactericide, 0.05-5% of water-soluble chitosan, 0-7% of solvent, 0.3-1.5% of water-soluble high molecular materials, 0.1-1% of triethanolamine, 0.05-0.5% of chelating agent, 0.05-0.5% of emollient and the balance of distilled water. The gel medical supply comprises the gel, a far infrared textile fabric, a self-heating bag and a surfactant, wherein the far infrared textile fabric is dipped in the surfactant and then dried to be packed with the self-heating bag and the gel together. The gel medical supply for preventing the bedsore disclosed by the invention has the functions of cleaning the skin, preventing the bacteria, diminishing the inflammation, preventing the allergy, prompting the blood circulation and the metabolism and strengthening the immunity of apart of skin; in addition, the gel medical supply for preventing the bedsore contains natural skin-care elements, and massage can prompt the absorption and the metabolism of the gel medical supply byutilizing the far infrared textile fabric and the self-heating bag with the surfactant so that the effects of cleaning and treating are realized at the same time.

The invention discloses a marine biological peptide acne-removing and repairing mask and a preparation method thereof and belongs to the technical field of cosmetics. The marine biological peptide acne-removing and repairing mask is composed of mask base cloth and a mask matrix solution, wherein the mask matrix solution is prepared from 0.1 to 0.3 percent of hydroxyethyl cellulose, 1 to 5 percentof pentylene glycol, 1 to 5 percent of butylene glycol, 0.1 to 0.3 percent of allantoin and 1 to 3 percent of niacinamide; a polypeptide composition is prepared from 0.1 to 1 percent of deep sea fishskin collagen peptide, 0.1 to 1 percent of sea cucumber collagen peptide, 0.02 to 0.2 percent of fish roe polypeptide, 0.05 to 0.2 percent of dipotassium glycyrrhizinate, 0.1 to 0.5 percent of aloe freeze-dried powder and the balance of water. According to the mask disclosed by the invention, the content of microorganisms and heavy metal meets national standards; the mask has no irritation on skin, no toxic and side effects on cells and no sensitization on the skin; the acne-removing effect is obvious and is better than that of commercial products.

A composite herbicide for cane field contains ametryn (30-45 wt.%), MCPA sodium (3-13), surfactant (3-10) and inertial filler (30-39). Its advantages are high effect (more than 92%), and no damage to cane.

The invention belongs to the technical field of medicine compositions, and discloses an external use medicine composition used for treating alopecia. The external use medicine composition comprises annular adrenocorticotrophic hormone release factor (CRF) antagonism peptide astressin B in effective treatment amount or acceptable salt on the pharmacy. The external use medicine composition is in a gel dosage form preferably and suitable for clinic use and industrialization production. In addition, the invention further discloses a method for preparing the external use medicine composition and application of the astressin B in effective treatment amount or the acceptable salt on the pharmacy to preparing the external use medicine composition used for treating the alopecia. According to the external use medicine composition, the problem of the alopecia for a long time can be effectively treated; and the external use medicine composition is safe, reliable, free of obvious skin irritants and free of sensitization.

The invention relates to a bisultap and phoxim compound disinsection composition. The disinsection composition comprises bisultap and phoxim which are in weight ratio of 1:30-30:1, the total of bisultap and phoxim in the composition accounts for 0.1 percent to 50 percent of the total weight of the composition, and the insecticide further comprises an agricultural suitable carrier including at least one of surface-active agent, solid or liquid diluent. The insecticide has a better control effect in preventing soil inserts of sugarcane, and is safe for sugarcane.

The invention relates to medicine composition for treating burn wound and a preparation method thereof. The medicine composition consists of angelica dahurica, radix paeoniae rubra, radix scrophulariae, rhubarb, radix rehmanniae, angelica, cortex phellodendri, salivia chinensis, rhizoma coptidis, szechuan lovage rhizome, radix paeoniae alba and vegetable oil. The preparation method comprises the steps: placing the angelica dahurica, the radix paeoniae rubra, the radix scrophulariae, the rhubarb, the radix rehmanniae, the angelica, the cortex phellodendri, the salivia chinensis, the rhizoma coptidis, the szechuan lovage rhizome, the radix paeoniae alba and the vegetable oil into a gauze after oil-immersion, mixing, heating and filtering. The medicine composition belongs to the secret recipe of the pure Chinese Traditional medicine, uses traditional medicine materials as raw materials and is prepared by adopting scientific proportion so as to dredge the channels and collaterals, remove pattogenic heat from the blood and toxic material from the body, activate blood and dissolve stasis, relieve swelling and pain and remove the rotten and let fresh grow, recover energy with biochemical operation, activate metabolism and enhance self-immunity function so that the surface of the wound hurt by the burn wound can obtain regenerative repair. The medicine composition can be used for treating various kinds of fire burn, scalding, trauma, abscess, bedsore, scarring and angiitis, various kinds of skin infections, and the like. Due to no pain for treating the burn injury without skin graft, smooth wound surface treated in third-degree burn injury, no obvious scar, the medicine composition is an external treatment with no toxity, no incitement, no senitization, safe and good healing efficacy, and can be applied to emergency treatment for burn injury.

The present invention discloses an edible fruit and vegetable cleaning agent, which at least comprises two poly glyceride surfactants and food-grade glycerine. The prepared edible fruit and vegetable cleaning agent of the present invention has the following advantages that: (1) the prepared edible fruit and vegetable cleaning agent is a liquid reagent, and is easy to use; (2) the used raw materials are the food-grade raw materials, such that the secondary harm caused by the surfactant residue does not exist; (3) the used poly glyceride surfactants have characteristics of good biodegradability, environment protection, and no harm; (4) the used poly glyceride surfactants can be decomposed into glycerine and fat during the metabolic process in the human body, and the obtained glycerine and the obtained fat can be utilized by the human body to participate in metabolism so as to provide high safety; and (5) the prepared edible fruit and vegetable cleaning agent is mild and nonirritant, and does not produce the sensitization phenomenon.

The invention belongs to the field of medical preparations, and relates to cefozopran hydrochloride for injection and a preparation method thereof. The cefozopran hydrochloride for injection comprises the following components in part by weight: 200 to 1,000 parts of cefozopran hydrochloride, 350 to 2,000 parts of soybean lecithin, 150 to 450 parts of cholesterol, 45 to 100 parts of anhydrous sodium carbonate and 25 to 85 parts of glucose. The cefozopran hydrochloride for injection can achieve better treatment effect on the basis of low content of a main ingredient, and simultaneously reduces the incidence rate of untoward effect, so the product is more safe and effective.

The present invention is the application of osthole in prepare medicine for treating pruritus caused by acute and chronic dermatitis. Osthole is obtained through the technological process of ethanol extraction, petroleum separation and refining; and is used as active component in preparing medicine liquid or medicine ointment for treating pruritus caused by acute and chronic dermatitis via combination with excipient and / or carrier. The preparation contains osthole in 0.1-10 wt%. The preparation process is simple, stable in quality, high in total yield. Pharmacological and toxicologic experiments show that the medicine has the functions of stopping itching, eliminating inflammation and resisting type-I and type-IV allergic reaction, no acute toxicity, no skin irritation, no hypersusceptibility, and obvious curative effect on pruritus caused by acute and chronic dermatitis.

The invention relates to an external medicament, in particular to an infusion medicament analgesic patch which is used for relieving pain in the process of intravenous infusion. The patch comprises a polyurethane transparent film and an absorbent pad fixed on the polyurethane transparent film, wherein the analgesic liquid medicine soaked in the absorbent pad is formed by mixing a nitroglycerin solution the mass percent concentration of which is 2-3% and a lidocaine hydrochloride solution the mass percent concentration of which is 0.5-1.5%, and the volume ratio of the nitroglycerin solution to the lidocaine hydrochloride solution is (2.5-3.5):1. When a patient is treated by intravenous infusion of medicaments such as potassium chloride and the like, the analgesic patch can effectively relieve the pain caused by infusion of the medicaments and has higher safety in clinical application.

The present invention is Chinese medicine composition for treating women's diseases and its production process. The externally applied medicine is used in treating women's inflammation caused by trichomonas vaginalis, fungus and bacteria. The Chinese medicine composition contains honeysuckle, sessile stemona root, phellodendron bark and other plant medicine materials, borax and borneol.

The invention discloses silicone rubber synthetic leather for a medical device. The silicone rubber synthetic leather comprises a cloth base orderly coated with a silicone rubber layer for a medical device and a surface layer for the medical device. The surface layer for the furniture in the hospital and the nursing institution comprises, by mass, 30-50 parts of high viscosity vinyl silicone oil,10-20 parts of vinyl MQ resin, 10-20 parts of vinyl phenyl silicone resin, 3-10 parts of high hydrogen content silicone oil, 10-20 parts of silicon micropowder, 0.05-0.1 part of a platinum catalyst and 0.01-0.03 parts of a retardation agent. The silicone rubber synthetic leather has excellent high and low temperature resistance, weather resistance and hydrolysis resistance, excellent skin-friendlyproperties, no cytotoxicity, no sensitization and no irritation or intradermal reaction. A preparation method of the silicone rubber synthetic leather has simple processes, high production efficiencyand low cost.

The invention discloses a facial injection filling agent for cosmetic plastic surgery. The facial injection filling agent is prepared from the following raw materials: 4 to 6 ml of hyaluronic acid, 0.3 to 0.6 g of beta-tricalcium phosphate, 0.1 to 0.3 g of collagen powder, 0.3 to 0.5 g of an excipient, 0.1 to 0.3 g of vitamin powder and 6 to 8 ml of water for injection. According to the facial injection filling agent disclosed by the invention, the hyaluronic acid and beta-tricalcium phosphate particles are mixed to form suspension; the collagen powder, the excipient and the vitamin powder are added, so that the facial injection filling agent has very high compatibility and no sensitization is generated after injection; and meanwhile, the hyaluronic acid is selected and is mixed with the beta-tricalcium phosphate particles, so that filling of different parts of a face can be realized and the application range is relatively wide.

The invention discloses a skin cleaning solution. The skin cleaning solution is prepared by the following raw materials by mass percent: 5-20% of sodium laureth sulphate, 2-7% of glycerine, 2-7% of lauryl dimethyl benzyl amine bromide, 1-3% of sodium chloride, 2-7% of coconut diethanol amide and 0.2-0.4% of peppermint oil, and the balance of deionized water. The skin cleaning solution disclosed in the invention has pleasant smell after use, skin is fresh, cool and smooth after the skin cleaning solution is used, test result shows that the skin cleaning solution disclosed in the invention has strong bacteriostasis effect and has no skin acute absorption toxicity on injured and complete skins of rats; the skin cleaning solution is light and is easy to carry; and after the skin cleaning solution disclosed in the invention is used, systemic skin can be cleaned by only 250ml of water, thus water is saved. The skin cleaning solution disclosed in the invention can be applicable to skin cleaning of field operating personnel, officers and soldiers in special environment and seriously ill personnel in a hospital.

The invention discloses a double-agent melanin precursor hair dye and a three-agent melanin precursor hair dye. The double-agent melanin precursor hair dye comprises an agent A and an agent B; the three-agent melanin precursor hair dye comprises an agent A, an agent B and an agent C; the agent A and the agent C both comprises melanin precursors, common hair dye auxiliaries and water; the common hair dye auxiliaries refer to one or more of a wetting agent, a thickening agent, a surfactant, a moisturizing agent and a pH value regulating agent. By combination of advantages of chemical synthesized hair dye and natural hair dye, compound enzyme liquor in natural edible fungi is extracted, amino acids are subjected to bioconversion to synthesize melanin precursor substances such as hallachrome, 5,6-dyhydroxyindole and 5,6-dyhydroxyindole-2-carboxylic acid, skin irritation and allergization are avoided, high safety is achieved, and natural black hair dyeing effects are kept. In addition, due to various agent type choices, the multi-agent melanin precursor hair dye has a great popularization and application value in the field of hair dye preparation.

The invention discloses a cleaning skin moisturizer which is prepared from the following raw materials in percentage by weight: 10-20% of glycerin, 1-3% of glycerin, 2-7% of cocoanut diethanol amide (CDEA), 10-30% of ethanol, 0.2-0.4% of peppermint oil, a proper amount of essence, and the balance deionized water. By using the cleaning skin moisturizer provided by the invention, the odour is pleasant, and the skin is refreshing and smooth. The test result proves that the cleaning skin moisturizer has stronger bacteriostatic efficacy, non skin acute absorption toxicity for damaged or complete skin of the rat; and the cleaning skin moisturizer is easy to take, is in no need of washing after being used, has good cleaning effect, and long cleaning effect time. The cleaning skin moisturizer can be suitable for field operators, officers and men in militaries under special environments, and seriously injured personnel in hospitals.

The invention relates to a couplant for ultrasound and a preparation method thereof. The couplant comprises the following components in percentage by weight: 2-4 percent of chlorhexidine iodine, 3-6 percent of glycerol, 3-6 percent of sodium carboxymethyl cellulose, 12-15 percent of ethanol and 70-82 percent of deionized water. The preparation method of the couplant comprises the following steps of: adding the chlorhexidine iodine into the deionized water and dissolving to obtain a chlorhexidine iodine solution; adding sodium carboxymethyl cellulos into the ethanol and evenly stirring to obtain a mixed solution of the sodium carboxymethyl cellulos and the ethanol; and fully stirring and mixing the chlorhexidine iodine solution and the mixed solution of the sodium carboxymethyl cellulos and the ethanol to obtain the couplant for ultrasound. The invention has simple preparation process, kills bacteria and virus, has excellent functions for avoiding cross-infection and preventing hospital infection and is suitable for ultrasound examination of various hospitals.

The invention discloses a melanin precursor substance hair dye. The melanin precursor substance hair dye consists of a melanin precursor, a common hair dye adjuvant and water, wherein the melanin precursor includes dopachrome, 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid; the melanin precursor accounts for 0.01-5% of the hair dye in percentage by weight; and the common hair dye adjuvant includes one or more of a wetting penetrating agent, a thickening agent, a surfactant, a moisturizer and a pH value regulating agent. The hair dye disclosed by the invention combines the advantages of a chemically synthetic hair dye and a natural hair dye; by extracting complex enzyme liquid in natural edible fungi, such melanin precursor substances as the dopachrome, the 5,6-dihydroxyindole, the 5,6-dihydroxyindole-2-carboxylic acid and the like are synthesized through bio-conversion by virtue of amino acid, so that the hair dye is free from irritation and allergy to skin, high in safety and capable of keeping a natural black hair dyeing effect; and the hair dye has huge popularization and application values in the field of the preparation of hair dyes.

The invention discloses a medical ultrasonic disinfection coupling agent. The medical ultrasonic disinfection coupling agent comprises the following components in percentage by weight: 0.03 to 0.1% ofchlorhexidine gluconate, 0.002 to 0.01% of terpilenol, 0.1 to 0.5% of chitosan, 10 to 20% of a wetting agent, 0.8 to 1.6% of distearyl alcohol polyether, and 0.08 to 0.15% of a preservative, with thebalance being purified water. The invention also discloses a preparation method of the medical ultrasonic disinfection coupling agent. The medical ultrasonic disinfection coupling agent is colorless,non-toxic and non-irritant, has proper viscosity, good conductivity, low ultrasonic energy loss, high resolution ratio, clear ultrasonic development, high safety, and efficient, rapid and lasting disinfection and skin-moistening effects, can disinfect an ultrasonic probe at any time while realizing sterilizing, and avoids cross infection in clinical examination. In addition, the medical ultrasonic disinfection coupling agent is wide in raw material source, simple in preparation process, low in cost and easy to popularize and apply in the market.

The invention relates to medical slow-released analgesic dressing which comprises the following components and contents: remifentanil polymer slow-released analgesic drug is 2 to 4 parts by weight; gelatin is 10 to 20 parts by weight; the remifentanil polymer slow-released analgesic drug is obtained from the reaction between the remifentanil which is used as polymerization termination agent and caprolactone; the gelatin has the prescription that glycerin is 4 to 8 parts by volume, whiteruss is 3 to 6 parts by weight, polyvinyl alcohol is 2 to 4 parts by weight, and purified water is 25 to 50 parts by volume. The medical slow-released analgesic dressing has the preparation method and technical steps as follows: (1) the remifentanil polymer slow-released analgesic drug is prepared; (2) the gelatin is prepared; (3) the remifentanil polymer slow-released analgesic drug which is prepared in the step (1) and the gelatin which is prepared in the step (2) are stirred and mixed for 1 to 2 hours under the normal atmosphere to prepare the medical slow-released analgesic dressing, wherein, the remifentanil polymer slow-released analgesic drug is 2 to 4 parts by weight and the gelatin is 10 to 20 parts by weight, and the temperature is 40 to 60 DEG C.