External use medicine composition and preparing method thereof
A technology for external use of medicines and compositions, applied in the field of medicine synthesis, can solve the problems of differences in treatment effects, increase facial hair, reduce libido, etc., and achieve the effects of smooth appearance, easy coating and use, and suitable viscosity
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Embodiment 1
[0050] Embodiment 1: Preparation of low-dose pharmaceutical composition for external use
[0051] 1. Prescription
[0052]
[0053] 2. Preparation
[0054]Sprinkle Carbomer 940 in water and let it swell. Dissolve glycerin, propylene glycol, potassium sorbate, and salicylic acid in water and mix well. Add it to the above carbomer solution and mix evenly, adjust the pH to 6.0 with triethanolamine, and stir evenly to obtain a colorless transparent gel. The astressin-B is added to the above gel, stirred and mixed to obtain a low-dose pharmaceutical composition for external use.
Embodiment 2
[0055] Embodiment 2: the preparation of middle-dose pharmaceutical composition for external use
[0056] 1. Prescription
[0057]
[0058] 2. Preparation
[0059] Sprinkle Carbomer 940 in water and let it swell. Dissolve glycerin, propylene glycol, potassium sorbate, and urea in water, and mix well. Add it to the above carbomer solution and mix evenly, adjust the pH to 6.0 with triethanolamine, and stir evenly to obtain a colorless transparent gel. Dissolve menthol with 95% ethanol, add to the gel, and stir to mix. The astressin-B is added to the above gel, stirred and mixed evenly, and a medium-dose external pharmaceutical composition can be obtained.
Embodiment 3
[0060] Embodiment 3: Preparation of high-dose pharmaceutical composition for external use
[0061] 1. Prescription
[0062]
[0063] 2. Preparation
[0064] Spread hydroxyethyl cellulose in water and let it swell until it swells to obtain a colorless transparent gel. Add acetate buffer to control the pH of the gel at 5.5. Add glycerin, propylene glycol, sodium benzoate and water-soluble azone into the above gel, and stir evenly. The astressin-B is added to the above-mentioned gel and stirred evenly to obtain a high-dose pharmaceutical composition for external use.
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