The invention discloses a noni oral liquid and preparing method, wherein, the oral liquid consisting of the followings by weight: crude drug: noni 3 : 3 - 12 : 3, the crude drug comprising the following components: chrysanthemum budz, hawthorn fruit, liquorice root, peppermint, medlar, red dates, longans, dwarf lilyturf, boat-fruited sterculia, herbal tea, pericarpium citri reticulatae, angelica dahurica, ginseng, codonopsis, rhizoma chuanxiong, astragalus, rose, red ginseng, yellow skin dry, jasmine. Frequently taking oral liquid could increase immune system, improve fatigue, reduce blood viscosity, resist thrombus, subsidiarily treat the disease of heart head blood-vessel, lower blood pressure and blood fat, alleviate diabetes and other symptoms. The preparing method is mixing noni frementation broth and water extract stoste of various medicinal materials, the noni frementation broth could help Chinese herbal medicine playing efficacy and promote cells to absorb, playing the health care efficacy of enhancing immunity and resist fatigue.