The invention discloses a processing method of pitaya peel jam. The method comprises the following steps: taking fresh pitaya peel, removing pedicels, terminal buds and other crude fiber parts, blanching the pitaya peel, beating the blanched pitaya peel, adding a sweetener and calcium chloride, boiling the obtained mixture, and bottling the boiled mixture in order to make jam foods. The jam obtained in the invention is a red or pale yellow gel product, has suitable sweet-sour taste, has acceptant mouthfeel, has oxidation preventing, free radical preventing, ageing preventing, eyesight improving, internal heat reducing and other health effects, has good youth keeping and beauty maintaining effects, and also can improve cerebrocellular degeneration prevention and inhibit dementia. The jam produced in the invention is suitable for routine populations to eat, and sugar-free or low-sugar nutritional jam can be produced for patients with three highs to meet diabetic patients and hyperglycemia patients' demands for low-sugar or sugar-free high dietary fiber foods, so the consumer group of the product is enlarged.