Oral liquid preparation for curing wind-heat type cold and preparation method thereof
A liquid preparation, the technology of Fengreganmao, which is applied in the field of medicine, can solve problems such as poor taste, and achieve the effects of improving compliance, improving bitter taste, and increasing water solubility
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Embodiment 1
[0044] Example 1 Preparation of Chaiyin Oral Liquid
[0045] 1) Extraction and concentration process: (refer to the specification or Chinese invention patent ZL03100188.2, a traditional Chinese medicine composition for treating anemopyretic cold and its preparation method.)
[0046] Crush 0.5kg of bitter almonds, mix with 1.0kg of bupleurum, 0.75kg of honeysuckle, 0.5kg of nepeta, 0.75kg of artemisia annua, 0.75kg of forsythia, 0.75kg of mint, 0.75kg of houttuynia, etc., add 10 times the amount of water Soak for 1 hour, heat and distill for 2.5 hours, collect 4500ml of distilled liquid; release the leaching medicinal liquid after distillation, decoct the dregs with 0.6kg of Scutellaria baicalensis, 0.5kg of Platycodon grandiflora, and 0.5kg of Pueraria radiata three times, and add 8 times the amount of water for the first time , decoct for 1.5 hours, add 6 times the amount of water for the second time, decoct for 1.0 hour, add 6 times the amount of water for the third time, an...
Embodiment 2
[0049] Example 2 Preparation of Chaiyin Oral Liquid
[0050] 1) Extraction and concentration process:
[0051] See embodiment 1;
[0052] 2) Preparation process:
[0053] Filter the water extract, add purified water to the filtrate to 7500ml, adjust the pH to 7.2, add a total of 1.5% α-cyclodextrin, control the inclusion temperature at 20-30°C, stir for 60 minutes, filter, and the filtrate Add 40% sucrose and 0.2% sodium benzoate in the total amount of preparation, stir to dissolve, add purified water to 7500ml, filter until the clarity is qualified, and then fill, the specification is 20ml / cartridge, sterilized by circulating steam at 100°C for 60 minutes, and packaged. .
Embodiment 3
[0054] Example 3 Preparation of Chaiyin Oral Liquid
[0055] 1) Extraction and concentration process:
[0056] See embodiment 1;
[0057] 2) Preparation process:
[0058] Filter the water extract, add purified water to the filtrate to 7500ml, adjust the pH to 7.2, add 1.5% gamma-cyclodextrin in total, control the clathrate temperature at 20-30°C, stir clathrate for 60 minutes, filter, and filtrate Add 40% sucrose and 0.2% sodium benzoate in the total amount of preparation, stir and dissolve, add purified water to 7500ml, filter until the clarity is qualified, and then fill it. have to.
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