113results about How to "Highly selective" patented technology

An Fc-binding polypeptide of improved alkali stability, comprising a mutant of an Fc-binding domain of Staphylococcus Protein A (SpA), as defined by SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO:3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:22, SEQ ID NO 51 or SEQ ID NO 52 wherein at least the asparagine or serine residue at the position corresponding to position 11 in SEQ ID NO:4-7 has been mutated to an amino acid selected from the group consisting of glutamic acid, lysine, tyrosine, threonine, phenylalanine, leucine, isoleucine, tryptophan, methionine, valine, alanine, histidine and arginine.

The invention discloses a method of utilizing replacement control and herbicide application to control mikania micrantha, and belongs to the technical field of comprehensive prevention and control to the exotic invasion pest. The method comprises the following steps: when mikania micrantha is emerged and grows for 30 days, planting and sticking simple-link sweet potato seedlings with length of 5-7 cm for 10 days between the mikania micrantha seedlings, and at the same time, spraying bentazone at the dosage of 48-72 g/mu. Compared with the single application of bentazone, 60-90 days after administration, the control effect is improved by 2.52-20.44%; compared with the single sweet potato replacement control, 60-90 days after administration, the control effect is improved by 14.12-38.39%; compared with the single application of bentazone at the dosage of 72 g/mu, the dosage is reduced by 33% when the planting density ratio of the sweet potato to mikania micrantha is 2.6:1, and the control effect is improved by 0.2-1.51%, 60-90 days after administration. The method has the characteristics of high efficiency, safety and long-lasting control.

A polypeptide with improved alkaline stability, which polypeptide comprises a mutant of a B or C domain of Staphylococcus Protein A, as specified by SEQ ID NO 1 or SEQ ID NO 2, or of Protein Z, as specified by SEQ ID NO 3, wherein at least the glutamine residue at position 9 has been mutated to an amino acid other than asparagine. The invention also discloses multimers of said polypeptide, as well as separation matrices comprising the multimers or polypeptides.

A separation membrane comprising a polyether polymer having a weight-average molecular weight of 104 to 107 and obtained by polymerizing an oxirane compound of the formula: wherein R is a hydrogen atom; an alkyl group, an alkyl group having an halogen atom, or -CH2O(CH2CH2O)k-R' (R' is a group selected from an alkyl group, an alkenyl group, a cycloalkyl group, an aryl group and an aralkyl group; k is from 0 to 12.); or an ethylenically unsaturated group, a reactive silicon-containing group or a methylepoxy-containing group, is excellent in mechanical strength and flexibility.

The invention relates to an ultraviolet detector, in particular to an ultraviolet detector with high spectral selectivity and high sensitivity and a preparation method of the ultraviolet detector. A beta-Ga<2>O<3> film is deposited on an n-type 4H-SiC substrate through a laser molecular beam epitaxy technique; and a Ti/Au film is deposited on the n-type 4H-SiC substrate and the beta-Ga<2>O<3> film for use as an electrode by a mask through a radio-frequency magnetron sputtering technique. The ultraviolet detector has the advantages that the prepared ultraviolet detector has stable performance, has high selectivity and high sensitivity on an ultraviolet spectrum with a specific wavelength, is low in dark current, and can be applied to fire alarm, high-voltage line corona and detection of the spectrum with the specific wavelength; furthermore, the preparation method has the characteristics of being high in process controllability, simple in operation, good in universality and the like and has a great application prospect; and a repeated test has recoverability.

Disclosed are A₃ adenosine receptor antagonists and/or partial agonists of formula (I): wherein R¹ to R⁵ are as described herein, as well as pharmaceutical compositions thereof and methods of use thereof. The antagonists or partial agonists find use in treating a number of diseases including cancer, glaucoma, inflammatory diseases, asthma, stroke, myocardial infarction, allergic reactions, rhinitis, poison ivy induced responses, urticaria, scleroderma, arthritis, brain arteriole diameter constriction, bronchoconstriction, and myocardial ischemia, as well as in preventing cardiac ischemia. Also disclosed are radiolabeled compounds of formula (I) and the use thereof in diagnostic imaging of tissues and organs.

The present invention relates to a catalyst for reducing mercury, which comprises a reagent comprising any of the sulfites of potassium, sodium, calcium and magnesium, or any of the phosphates thereof, or a combination of them, as a main reagent of a catalyst component. And the present invention relates to the catalyst for reducing mercury, wherein the catalyst component is mixed with a different salt as an agent for inhibiting crystallization of the catalyst component.

The present invention provides a class of 2,4-substituted phenylene-1,5-diamine derivatives, having an inhibiting effect on EGFR tyrosine kinases, and pharmaceutically acceptable salt, stereoisomer, solvate or prodrug of said derivatives. See the description for the definition of each group in the formula. In addition, the present invention also discloses pharmaceutical compositions, pharmaceutically acceptable compositions and applications thereof.

The invention relates to a separation matrix comprising at least 11 mg/ml Fc-binding ligands covalently coupled to a porous support, wherein: a) the ligands comprise multimers of alkali-stabilized Protein A domains, and b) the porous support comprises cross-linked polymer particles having a volume-weighted median diameter (d50,v) of 56-70 micrometers and a dry solids weight of 55-80 mg/ml.

Provided is a method for producing a rice F1 seed including crossing a rice male sterile line of Koshihikari containing one or more genes selected from the group consisting of the Pb1 gene derived from a rice (Oryza sativa L) cultivar Modan and the Cr1 gene derived from Oryza nivara, as a seed parent, with a rice fertility restorer line as a pollen parent, and collecting the first filial generation seed (F1 seed) from the post-crossing seed parent; a rice F1 seed which is obtained by the above-described method for producing a rice F1 seed; and a rice cytoplasmic male sterile line including one or more genes selected from the group consisting of the Pb1 gene derived from rice (Oryza sativa L) cultibar Modan, and the Cr1 gene derived from Oryza nivara.

Provided is a facilitated CO₂ transport membrane having an improved CO₂ permeance and an improved CO₂/H₂ selectivity. The facilitated CO₂ transport membrane includes a separation-functional membrane that includes a hydrophilic polymer gel membrane containing a CO₂ carrier and a CO₂ hydration catalyst. Further preferably, the CO₂ hydration catalyst at least has catalytic activity at a temperature of 100° C. or higher, has a melting point of 200° C. or higher, or is soluble in water.

The present invention is a method and apparatus for treating a substrate using an impingement cryogenic or steam spray jet whereas a substrate is first encased in a prophylactic device whereupon the substrate is continuously bathed in a counterflowing stream of ULPA-filtered, inert, dry, heated and ionized gas which bathes both the posterior and anterior regions of the critical substrate surface to be treated-precluding the intrusion of contaminating atmospheres onto critical surfaces. This creates an in-situ microenvironment within which the substrate surface is treated with said impinging treatment spray. The treated surface is thus isolated and protected from the ambient atmosphere and contaminants contained therein prior to, during and following application of a treatment spray without causing a direct impingement of a protective atmosphere upon a critical surface. The critical substrate surfaces being treated are continuously supplied heat, ions and a diluting atmosphere through molecular diffusion phenomenon rather than through direct impingement purging, drying or ion bombardment, thereby minimizing or eliminating the creation or introduction of contaminants into or within the cleaning zone. The present invention allows for the simultaneous application of a variety of conventional surface treatment agents such as dry steam or snow to a critical surface while controlling and maintaining the quality of the environment immediately within the vicinity of the critical surface being treated.

The invention discloses a preparation method of an absorbent for effectively reducing phenol content in cigarette smoke. The preparation method comprises the following steps: preparing a phenol imprinting polymer by molecular imprinting technology and a bulk polymerization method, and obtaining the absorbent of which surface is porous and contains a plurality of holes matched with phenol molecules in structure and shape; and the absorbent has high selectivity to phenol. The absorbent is added into a ternary composite rod, the addition amount can be regulated as required, when the addition amount is 10 mg/cigarette, compared with a comparing sample, the reduction rate of phenol in cigarette smoke is 17.8%, and the relative reduction rate relative to tar is 11.8%; and when the addition amount is 20 mg/cigarette, the reduction rate of phenol in cigarette smoke is 28.7%, and the relative reduction rate relative to tar is 12.3%. The method is simple to operate, low in cost and convenient for a large-scale industrial production.

The invention discloses a preparation method of an adsorbent capable of reducing nicotine content in cigarette smoke. The preparation method comprises the following steps: performing molecular imprinting by a sacrifice silica gel skeleton method, after imprinting, removing silica gel by using hydrofluoric acid to solute, and obtaining microspheres with a molecular recognition function. The microspheres basically keep the shapes of primary silica gel microspheres, and have greater hole volumes and specific surface areas, a plurality of reaction sites and higher selectivity and adsorption capacity. The absorbent is applied to a composite rod, the addition amount can be regulated as required, when the addition amount is 10 mg/cigarette, compared with a comparing sample, the reduction rate of nicotine in cigarette smoke is 23.8%, and the relative reduction rate relative to tar is 10.4%; and when the addition amount is 20 mg/cigarette, compared with a comparing sample, the reduction rate of nicotine in cigarette smoke is 43.7%, and the relative reduction rate relative to tar is 23.4%; thus the effect of selectively reducing nicotine is very obvious.