Belonging to the technical field of
calcium ion detection, the invention discloses an aggregation induced luminescent probe, preparation and application thereof in
calcium ion detection and imaging. The aggregation induced luminescent probe has a structure shown as formula I, wherein R is
hydrogen,
alkyl, perfluoroalkyl, alkoxy, alkylthiol,
alkyl amino,
halogen, cyano, nitro, or heteroaryl; X is axial bond or alkylidene; Y is axial bond, arylidene, or heteroarylidene; A<+> is a cation. The aggregation induced luminescent probe is used for
calcium ion detection and imaging. The probe for calcium ion detection has the characteristics of wide response range, strong
fluorescence, high lightening ratio up to 10 times or more, and high
signal-to-
noise ratio, effectively overcomes the defect of aggregation
quenching luminescence in traditional
fluorescent materials. At the same time, the probe has the advantages of simple preparation, low cost and convenient operation, is suitable for specific imaging and detection in
high concentration aggregation areas of calcium ions, and has good detection effect.